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881
A polysaccharide-based hydrogel platform for tumor spheroid production and anticancer drug screening
Published 2025-02-01“…Abstract Extracellular matrix mimics are still needed to grow cancer cells in 3D environments and study their evolution in vitro while precisely controlling relevant features. …”
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882
Identification of disulfidptosis-related subtypes in gastric cancer and GAMT is a key gene during disulfidptosis
Published 2025-01-01“…Inhibiting the expression of GAMT genes associated with disulfidptosis subtypes can significantly inhibit the proliferation of gastric cancer cells, which may be an important target for gastric cancer treatment. …”
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883
Secoxyloganin inhibits growth of breast cancer MDA-MB-231 cells via induction of apoptosis and cell cycle arrest
Published 2024-12-01“…This study was set to study the anti-proliferative effects of secoxyloganin in MDA-MB-231 breast cancer cells. The MTT cell viability assay results demonstrated that secoxyloganin significantly (p < 0.05) inhibited the growth of the MDA-MB-231 cells with an IC50 of 6.5 μM which was significantly (p < 0.05) lower than the IC50 of 38 μM against the normal fR2 cells. …”
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884
Lentivirus-based production of human chimeric antigen receptor macrophages from peripheral blood
Published 2025-01-01“…Using our lentiviral protocol, we produced functional CAR macrophages to lyse and phagocytose target cancer cells efficiently.…”
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885
The mycobiome in human cancer: analytical challenges, molecular mechanisms, and therapeutic implications
Published 2025-01-01“…The interaction between cancer cells, immune cells, and microbiota is defined as the immuno-oncology microbiome (IOM) axis. …”
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886
Differentially regulated ADAMTS1, 8, 9, and 18 in pancreas adenocarcinoma
Published 2017-12-01“…The extracellular matrix (ECM) is a physiological barrier that limits the spread of cancer cells into surrounding tissues and distant organs. …”
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887
St-N, a novel alkaline derivative of stevioside, reverses docetaxel resistance by targeting lysosomes in vitro and in vivo.
Published 2024-01-01“…Lysosome targeting is an effective method for overcoming drug resistance in cancer cells. St-N (ent-13-hydroxy-15-kaurene-19-acid N-methylpiperazine ethyl ester) is a novel alkaline stevioside derivative with an amine group. …”
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888
Effect of Static Magnetic Field on Oxidant/Antioxidant Parameters in Cancerous and Noncancerous Human Gastric Tissues
Published 2016-01-01“…This event caused by SMF might play part in the death of cancer cells, which may be a good supportive vehicle for the cancer therapy.…”
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889
Modeling critical dosing strategies for stromal-induced resistance to cancer therapy
Published 2025-02-01“…We explore an experimental dataset from colorectal cancer cells treated with anti-EGFR targeting therapy, cetuximab, where cancer-associated fibroblasts increase epidermal growth factor secretion under treatment. …”
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890
Complexation by γ-cyclodextrin as a way of improving anticancer potential of sumanene
Published 2024-11-01“…This work provides the method how to focus the cytotoxic action of sumanene toward cancer cells using supramolecular assembly strategy, paving the way to the further exploration of biological properties of sumanene-containing supramolecular systems with bioactive features and applications of this buckybowl in general.…”
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891
Clinicopathological importance of immunohistochemical expression of OCT4, c-MYC and Ki-67 in colorectal cancer
Published 2024-12-01“…Cancer stem cells (CSCs) are cancer cells responsible for cancer initiation, growth, metastasis, recurrence and resistance to treatment. …”
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892
AXL: shapers of tumor progression and immunosuppressive microenvironments
Published 2025-01-01“…AXL is highly associated with tumor progression; however, previous studies on AXL have been limited to its impact on the biological behavior of cancer cells. An increasing body of research now demonstrates that AXL can influence the function and differentiation of immune cells, mediating immune suppression and thereby fostering tumor growth. …”
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893
Prostate Cancer Bone Metastasis: Molecular Mechanisms of Tumor and Bone Microenvironment
Published 2025-02-01“…The tumor microenvironment, comprising diverse cellular and non-cellular elements, interacts with prostate cancer cells to affect tumor growth and bone metastasis. …”
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894
Potential of Black Phosphorus in Immune-Based Therapeutic Strategies
Published 2022-01-01“…For example, BP under irradiation can convert near-infrared (NIR) light into heat and reactive oxygen species (ROS) to damage cancer cells, called photothermal therapy (PTT) and photodynamic therapy (PDT). …”
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895
Broadening horizons: research on ferroptosis in lung cancer and its potential therapeutic targets
Published 2025-01-01“…This review summarizes the biological mechanisms of ferroptosis, analyzes the regulatory factors of ferroptosis in lung cancer cells and their interaction with the tumor microenvironment, and further explores potential therapeutic strategies targeting ferroptosis. …”
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896
Resveratrol, Piceatannol, Curcumin, and Quercetin as Therapeutic Targets in Gastric Cancer—Mechanisms and Clinical Implications for Natural Products
Published 2024-12-01“…Resveratrol, naturally found in red grapes, has been shown to induce apoptosis and inhibit the proliferation, migration, and invasion of gastric cancer cells. Piceatannol, a metabolite of resveratrol, shares similar anticancer properties, particularly in modulating autophagy. …”
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897
Cellular Response upon Stress: p57 Contribution to the Final Outcome
Published 2015-01-01“…This review focuses on the contribution that p57 holds in regulating cell cycle arrest, apoptosis, and senescence after cellular stress with particular attention to the response of cancer cells.…”
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898
Biomarkers as Key Contributors in Treating Malignant Melanoma Metastases
Published 2012-01-01“…At the present time, at least three hypotheses were identified that may explain melanoma aetiology, as follows: (1) a model of linear progression from differentiated melanocytes to metastatic cancer cells (2) a model involving the appearance of melanoma stem-like cells, and (3) an epigenetic progenitor model of cancer. …”
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899
X-Ray Fluorescence Microscopy Demonstrates Preferential Accumulation of a Vanadium-Based Magnetic Resonance Imaging Contrast Agent in Murine Colonic Tumors
Published 2015-05-01“…This is the first direct demonstration that VCs selectively accumulate in cancer cells and thus may improve cancer detection.…”
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900
Manganese-Enhanced Magnetic Resonance Imaging for Early Detection and Characterization of Breast Cancers
Published 2014-09-01“…Eighteen NOD scid gamma mice were inoculated with MCF7, MDA, and LM2 breast cancer cells and imaged periodically on a 3 T scanner beginning on day 6. …”
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