Integral invariant manifold method applied to a mathematical model of osteosarcoma by Ophir Nave

“…By applying the MIM method, two critical dynamic variables (Cancer cells and Necrotic cells) were identified, providing insights into the dynamics of osteosarcoma over time during treatment.…”
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Effect of extracellular vesicle ZNF280B derived from lung cancer stem cells on lung cancer progression by Qixia Guo, Jiayan Lu, Hui Zhao, Ding Zhou, Hua Liu

“…Next, CCK-8 and colony formation assays were conducted to assess the effects of lung CSCs-EVs and ZNF280B on cancer cell proliferation, migration (via wound healing assay), and invasion (using transwell assay). …”
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New insights into Notch signaling as a crucial pathway of pancreatic cancer stem cell behavior by chrysin-polylactic acid-based nanocomposite by Eman M. Ragab, Doaa M. El Gamal, Fares F. El-najjar, Hager A. Elkomy, Mahmoud A. Ragab, Mariam A. Elantary, Omar M. Basyouni, Sherif M. Moustafa, Shimaa A. EL-Naggar, Abeer S. Elsherbiny

“…Recent research indicates that malignant tumors are highly variable and consist of a tiny subset of unique cancer cells, known as cancer stem cells (CSCs), which are responsible for the beginning and spread of tumors. …”
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In vitro investigating of anticancer activity of focuxanthin from marine brown seaweed species by M. Karkhane Yousefi, M. Seyed Hashtroudi, A. Mashinchian Moradi, A.R. Ghasempour

“…The results showed that fucoxanthin extract from Dictyota. indica at 24-hour treatment and 50 µg/ml concentration has the most effective anticancer activity on the breast cancer cells line, without toxic effects to the normal cells. …”
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Synthesis of Zinc Oxide (ZnO)-Titanium Dioxide (TiO2)-Chitosan-Farnesol Nanocomposites and Assessment of Their Anticancer Potential in Human Leukemic MOLT-4 Cell Line by Abozer Y. Elderdery, Badr Alzahrani, Siddiqa M. A. Hamza, Gomaa Mostafa-Hedeab, Pooi Ling Mok, Suresh Kumar Subbiah

“…Several metal oxide nanoparticles, biopolymers, and phytochemicals have been discovered to target cancer cells selectively while inflicting low to no damage to healthy cells. …”
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Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma by Patrick Pearson, Kendra Smith, Nilita Sood, Elizabeth Chia, Alicia Follett, Michael B. Prystowsky, Simon Kirby, Thomas J. Belbin

“…While expression of these proteins in HEK-293 cells produced full-length protein, only truncated copies could be expressed in head and neck cancer cells (UM-SCC-1). The truncated version of ZNF154 protein increased doubling time and reduced cell migration in UM-SCC-1 cancer cells. …”
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Matrix metalloproteinase-3 is a potent prognostic factor associated with cell proliferation and migration in prostate cancer by Ai Sato, Kiyoshi Takagi, Mio Yamaguchi-Tanaka, Jotaro Okushima, Yuto Yamazaki, Akihiro Ito, Takashi Suzuki

“…Prostate cancer is a common malignancy in men around the world, and it is crucial to explore novel biomarkers to improve its treatment. Prostate cancer cells typically invade the surrounding stroma, and remodeling of the extracellular matrix (ECM) is a crucial step in the progress of prostate cancer. …”
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Volume-regulated anion channels conduct ATP in undifferentiated mammary cells and promote tumorigenesis in xenograft nude mouse by Kishio Furuya, Kishio Furuya, Hiroaki Hirata, Hiroaki Hirata, Takeshi Kobayashi, Hiroshi Ishiguro, Masahiro Sokabe, Masahiro Sokabe

“…In the nude mouse xenograft model, LRRC8A knockdown suppressed the tumorigenesis of subcutaneously implanted breast cancer cells. These results suggest that abundantly expressed VRACs are a conduit of ATP release in undifferentiated cells, including cancer cells.…”
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Activation of FGD5-AS1 Promotes Progression of Cervical Cancer through Regulating BST2 to Inhibit Macrophage M1 Polarization by Guokun Liu, Xuan Du, Li Xiao, Qing Zeng, QianLing Liu

“…The level of FGD5-AS1 and BST2 was detected by qRT-PCR in cervical cancer cells. FGD5-AS1 and BST2 expression was significantly upregulated in cervical cancer cells. …”
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Antitumor Effect of Demethylzeylasteral (T-96) on Triple-Negative Breast Cancer via LSD1-Mediate Epigenetic Mechanisms by Zhengjie Shen, Yongjuan Gu, Ruiyang Jiang, Heya Qian, Siyuan Li, Lixian Xu, Wenzhe Gu, Yun Zuo

“…MTT assay, Live and Dead cell assay, and TUNEL were used to observe the antitumor effect of breast cancer cells treated with T-96. siRNA of LSD1, Co-IP, and molecular docking were used to explore the direct target and mechanism of T-96. …”
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Impact of DLL3 Expression as Prognostic Factor in Extensive Stage of Small Cell Lung Cancer Treated With First‐Line Chemotherapy by Hohyung Nam, Soon‐Hee Jung, Jii Bum Lee, Jee Hyun Kong, Seungtaek Lim

“…DLL3 expression and the percentage of tumor cells with DLL3 positive among total cancer cells were analyzed microscopically and DLL3 high and DLL3 low were defined as the percentage of DLL3 positive tumor cells versus total cancer cells ≧ 75% and < 75%, respectively. …”
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Endoplasmic reticulum stress-related super enhancer promotes epithelial-mesenchymal transformation in hepatocellular carcinoma through CREB5 mediated activation of TNC by Anqi Wang, Sitong Yan, Jiatao Liu, Xiang Chen, Mengyao Hu, Xiao Du, Weijia Jiang, Zhipeng Pan, Lulu Fan, Guoping Sun

“…Mechanistically, CREB5 upregulates the transcription of tenascin-C (TNC) by directly binding to its promoter region, thereby promoting EMT in liver cancer cells. In summary, our findings suggest that ERS activation promotes EMT in liver cancer cells via SE-mediated upregulation of the CREB5/TNC pathway. …”
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Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT) by Chantel P. J. Rice, Vipin Shankar Chelakkot, Noah T. Conohan, Kensuke Hirasawa

“…PDT involves the administration of photoactive substances called photosensitizers (PS) that selectively accumulate in cancer cells and are subsequently excited/activated by irradiation with light at wavelengths of optimal absorbance. …”
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Genomic Imprinting and Cancer: From Primordial Germ Cells to Somatic Cells by Adele Murrell

“…The mechanisms whereby imprinting is maintained in somatic cells and then erased and reset in the germline parallels epigenetic changes that cancer cells undergo. This review summarises what we know about imprinting in stem cells and how loss of imprinting may contribute to neoplasia.…”
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18F-FDG PET/CT findings of erythema induratum by KyungAh Chun, MD, PhD

“…18F-FDG (fluorodeoxyglucose) accumulates in malignant tissues but also at the sites of infection and inflammation and in autoimmune and granulomatous diseases by the overexpression of distinct facultative glucose transporter (GLUT) isotypes (mainly GLUT-1 and GLUT-3) in cancer cells and inflammatory cells.A 75-year-old female with a history of skin rash with tenderness for 1 month underwent 18F-FDG positron emission tomography/computed tomography (PET/CT) to determine the presence of an underlying disease including malignant tumor. …”
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Evasion of Apoptosis as a Cellular Stress Response in Cancer by Simone Fulda

“…Apoptosis resistance may contribute to carcinogenesis, tumor progression, and also treatment resistance, since most current anticancer therapies including chemotherapy as well as radio- and immunotherapies primarily act by activating cell death pathways including apoptosis in cancer cells. Hence, a better understanding of the molecular mechanisms regarding how cellular stress stimuli trigger antiapoptotic mechanisms and how this contributes to tumor resistance to apoptotic cell death is expected to provide the basis for a rational approach to overcome apoptosis resistance mechanisms in cancers.…”
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Cell scale modeling of electropermeabilization by periodic pulses by Michael Leguèbe

“…Since clinical permeabilization protocols mostly submit cancer cells to trains of periodic pulses, we investigate on parameters that modify significantly the resulting permeabilization. …”
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Immunotherapeutic Potential of the Yellow Fever Virus Vaccine Strain 17D for Intratumoral Therapy in a Murine Model of Pancreatic Cancer by Alina S. Nazarenko, Yulia K. Biryukova, Kirill N. Trachuk, Ekaterina A. Orlova, Mikhail F. Vorovitch, Nikolay B. Pestov, Nick A. Barlev, Anna I. Levaniuk, Ilya V. Gordeychuk, Alexander S. Lunin, Grigory A. Demyashkin, Petr V. Shegai, Andrei D. Kaprin, Aydar A. Ishmukhametov, Nadezhda M. Kolyasnikova

“…<b>Methods</b>: The cytopathic effect of YFV 17D on mouse syngeneic pancreatic cancers cells were studied both in vitro and in vivo and on human pancreatic cancers cells in vitro. …”
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Herbal based nanoparticles as a possible and potential treatment of cancer: a review by Roshan Yadav, Himmat Singh Chawra, Gaurav Dubey, Md Sabir Alam, Vikram Kumar, Pragya Sharma, Navneet Kumar Upadhayay, Tejpal Yadav

“…Nanoparticles may better identify and bind to cancer cells when functionalized with ligands. Natural chemicals and nanotechnology may improve medication availability, distribution, and targeting to cancer cells, making cancer treatments more effective and safe. …”
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FTO Facilitates Cervical Cancer Malignancy Through Inducing m6A‐Demethylation of PIK3R3 mRNA by Bingxin Chen, Liming Wang, Xiaomin Li, Ci Ren, Chun Gao, Wencheng Ding, Hui Wang

“…After changing the FTO expression level by lentivirus transfection, the proliferation and metastasis ability of cervical cancer cells were detected both in vitro and in vivo. …”
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