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Calcium Signalling in Neurological Disorders, with Insights from Miniature Fluorescence Microscopy
Published 2024-12-01Subjects: “…calcium signalling…”
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Calcium Signaling in the Ventricular Myocardium of the Goto-Kakizaki Type 2 Diabetic Rat
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Effects of the dynamics of noise-induced calcium signals in a biophysical model of the astrocytic process
Published 2025-01-01Subjects: Get full text
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Intracellular Membrane Contact Sites in Skeletal Muscle Cells
Published 2025-01-01Subjects: Get full text
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TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet’s disease
Published 2024-10-01“…Mechanistically, FPP induces TRPM2-calcium signaling for neutrophil extracellular trap (NET) and proinflammatory cytokine productions, leading to vascular endothelial inflammation and damage. …”
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Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization
Published 2025-01-01Subjects: Get full text
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Identification of Potential Diagnostic Biomarkers of Carotid Atherosclerosis in Obese Populations
Published 2025-02-01Subjects: Get full text
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Mechanism of action of Xipayimaizibizi oral liquid on outlet obstruction-induced overactive bladder: An integrated study
Published 2025-01-01Subjects: Get full text
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Danggui-Shaoyao-San Can Ameliorate Alzheimer’s Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology
Published 2025-02-01Subjects: Get full text
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Progesterone induces meiosis through two obligate co-receptors with PLA2 activity
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Iron triggers TvPI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP2 signaling crucial for multiple pathogenic activities of the parasitic protozoan Tric...
Published 2025-02-01“…These findings highlight that TvArf220-mediated PIP2-calcium signaling cascade regulates actin cytoskeleton and cytopathogenicity of T. vaginalis. …”
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Calcium-mediated regulation of mitophagy: implications in neurodegenerative diseases
Published 2025-02-01“…Abstract Calcium signaling plays a pivotal role in diverse cellular processes through precise spatiotemporal regulation and interaction with effector proteins across distinct subcellular compartments. …”
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Machine learning-driven identification of critical gene programs and key transcription factors in migraine
Published 2025-01-01“…Gene program 1, identified through NMF, was enriched in the calcium signaling pathway, a known contributor to migraine pathophysiology. …”
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A Simple Method for Establishing Adherent Ex Vivo Explant Cultures from Human Eye Pathologies for Use in Subsequent Calcium Imaging and Inflammatory Studies
Published 2014-01-01“…Anterior lens capsule-lens epithelial cells (aLC-LECs) from cataract surgery and proliferative diabetic retinopathy (PDR) fibrovascular epiretinal membranes (fvERMs) from human eyes were used in the study. We hereby show calcium signaling in aLC-LECs by mechanical and acetylcholine (ACh) stimulation and indicate presence of ACh receptors in these cells. …”
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Cannabis sativa extracts inhibit LDL oxidation and the formation of foam cells in vitro, acting as potential multi-step inhibitors of atherosclerosis development.
Published 2024-01-01“…The effect of the cannabinoid extracts on the endocytic process was independent of the canonical cannabinoid receptors, CB1 and CB2, but related to the action of non-canonical receptors (TRPV1, TRPV4 and GPR55), involved in calcium signaling. Decreased levels of CD36 and OLR1 scavenger receptors were, at least partially, responsible for the diminished uptake of oxLDL induced by phytocannabinoids. …”
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