Prefibrotic Myelofibrosis Presenting with Multiple Cerebral Embolic Infarcts and the Rare MPL W515S Mutation by Stephen E. Langabeer, Lisa Lee Tokar, Laura Kearney, Cathal O’Brien, Kowshika Thavarajah, Aisling Barrett, John McManus, Hilary O’Leary

“…We describe the case of an elderly man with persistent thrombocytosis presenting with an ischemic cerebral event. Bone marrow biopsy showed evidence of prefibrotic myelofibrosis with targeted sequencing demonstrating the presence of the rare MPL W515S mutation. …”
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A Case of Philadelphia Chromosome Positive Myeloproliferative Neoplasm in a Pregnant Woman with Unusual Primary Myelofibrosis Features by Jason Koshy, Jack Alperin, Bagi Jana, Avi Markowitz, You-Wen Qian

“…The patient demonstrated some pathologic features that are commonly presented in PMF that included bone marrow reticulin fibrosis, leukoerythroblastosis, splenomegaly, and increased serum lactate dehydrogenase.…”
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Release of prostaglandin D2 by murine mast cells: importance of metabolite formation for antiproliferative activity by C. Haberl, L. Hültner, A. Flügel, M. Falk, S. Geuenich, W. Wilmanns, C. Denzlinger

“…We investigated the production of PGD2 by murine bone marrow-derived mast cells (BMMC) taking into consideration metabolism of PGD2 to PGD2 and Δ12-PGJ2. …”
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C-Arm Image-Based Surgical Path Planning Method for Distal Locking of Intramedullary Nails by Wei-En Hsu, Ching-Hsiao Yu, Chih-Ju Chang, Hung-Kang Wu, Tsong-Han Yu, Ching-Shiow Tseng

“…Due to the curvature of the bone marrow cavity, the intramedullary nail used in long bone fracture fixation can be deformed, causing displacement of the locking holes. …”
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Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report by Frank Verhoeven, Xavier Guillot, Mickaël Chouk, Clément Prati, Daniel Wendling

“…Blood exams highlighted the presence of a monoclonal B cell clone. Bone marrow concluded to a B cell lymphoma of the marginal zone. …”
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Waldenström Macroglobulinemia in Hepatitis C: Case Report and Review of the Current Literature by Ryan Nipp, Aaron Mitchell, Allyson Pishko, Ara Metjian

“…He was subsequently diagnosed with Waldenström macroglobulinemia on bone marrow biopsy. Conclusions. An up to date, comprehensive review of the literature suggests an association between hepatitis C and Waldenström macroglobulinemia. …”
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Dental Mesenchymal Stem/Stromal Cells and Their Exosomes by Peter Stanko, Ursula Altanerova, Jana Jakubechova, Vanda Repiska, Cestmir Altaner

“…Stem cells derived from human dental pulp tissue (DP-MSC) differ from the other mesenchymal stem cells prepared from bone marrow or adipose tissue due to their embryonic origin from the neural crest and are of special interest because of their neurotropic character. …”
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Apolipoprotein C-II Deposition Amyloidosis: A Potential Misdiagnosis as Light Chain Amyloidosis by Sadichhya Lohani, Emily Schuiteman, Lohit Garg, Dhiraj Yadav, Sami Zarouk

“…Monoclonal gammopathy evaluation revealed kappa light chain. Bone marrow biopsy revealed minimal involvement with amyloidosis with kappa monotypic plasma cells on flow cytometry. …”
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The Role of TLR4 on B Cell Activation and Anti-β2GPI Antibody Production in the Antiphospholipid Syndrome by Si Cheng, Haibo Wang, Hong Zhou

“…Our previous study demonstrated that Toll-like receptor 4 (TLR4) plays a vital role in the maturation of bone marrow-derived dendritic cells (BMDCs) from the mice immunized with human β2-glycoprotein I (β2GPI). …”
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Crotoxin Isolated from Crotalus durissus terrificus Venom Modulates the Functional Activity of Dendritic Cells via Formyl Peptide Receptors by A. P. Freitas, B. C. Favoretto, P. B. Clissa, S. C. Sampaio, E. L. Faquim-Mauro

“…Therefore, we evaluated the effect of CTX, CA or CB on the maturation of DCs derived from murine bone marrow (BM). According to data, CTX and CB—but not CA—induced an increase of MHC-II, but not costimulatory molecules on DCs. …”
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Structural and Functional Characterization of Deceased Donor Stem Cells: A Viable Alternative to Living Donor Stem Cells by Prakash N. Rao, Dayanand D. Deo, Misty A. Marchioni, Rouzbeh R. Taghizadeh, Kyle Cetrulo, Sharyn Sawczak, Jacob Myrick

“…Stem cells can be isolated from various human tissues including bone marrow (BM) and adipose tissue (AT). Our study outlines a process to isolate adult stem cells from deceased donors. …”
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Notch Regulation of Hematopoiesis, Endothelial Precursor Cells, and Blood Vessel Formation: Orchestrating the Vasculature by Vincenza Caolo, Daniel G. M. Molin, Mark J. Post

“…Notch signaling also regulates the function of endothelial progenitor cells (EPCs), which are bone-marrow-derived cells able to differentiate into ECs and which could be considered the adult correlate of the angioblast. …”
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Aplastic anemia in a patient with papillary thyroid carcinoma complicated with Hashimoto’s thyroiditis: a case report by Fei Wu, Yiwei Xiao, Rui Hai, Xiaodong Chen, Shanshan Liu, Xiangyu Zhou

“…Laboratory tests revealed a decrease in white blood cells (WBC), red blood cells (RBC), and platelet count (PLT). Bone marrow aspiration revealed an extremely low degree of hyperplasia of hematopoietic cells. …”
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Blastoid Variant Mantle Cell Lymphoma Expressing Aberrant CD3 and CD10 with Concurrent Small Lymphocytic Lymphoma: Establishment of a Clonal Relationship by B- and T-Cell Receptor... by Christopher L. Felten, Joel A. Chan, Dulce R. DeCastro, Jean Lopategui, Swapnil P. Rajurkar

“…Small lymphocytic lymphoma (SLL) was also present in the same lymph node and in the bone marrow. B- and T-cell gene rearrangement studies by PCR show the MCL and SLL to be clonally related. …”
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Mandible infiltration as a clinical signal of extramedullary B-cell acute lymphoblastic leukemia/lymphoma in a child: Report of a rare case by Paulo Victor Mendes Penafort, Lady Paola Aristizabal Arboleda, Sérgio Takashi Kussaba, Izilda Aparecida Cardinalli, Regina Maria Holanda de Mendonça, Márcio Ajudarte Lopes, Pablo Agustin Vargas, Alan Roger Santos-Silva

“…Histopathological examination revealed proliferation of CD10, CD43, CD79a, PAX-5, TDT, CD99, and FLI-1 positive small round blue cells, with a 49% lymphoblast infiltration in the bone marrow. Chemotherapy was administered, leading to disease control during the 5-year follow-up.…”
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Extramedullary Plasmacytoma of the Larynx Treated by a Surgical Endoscopic Approach and Radiotherapy by Massimiliano Pino, Filippo Farri, Pietro Garofalo, Fausto Taranto, Andrea Toso, Paolo Aluffi

“…Diagnosis of solitary EMP can be made only if studies for disseminated disease and X-ray and/or magnetic resonance imaging of the spine, pelvis, femurs, and humerus and bone marrow biopsy are negative. As there are no internationally established guidelines, treatment of EMP is mainly based on consensus of expert opinion.…”
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Density of Langerhans Cells in Nonmelanoma Skin Cancers: A Systematic Review by Joanna Pogorzelska-Dyrbuś, Jacek C. Szepietowski

“…Langerhans cells (LCs) are bone marrow-derived dendritic cells (DCs) that represent 2-3% of the entire cell population of the human skin, known to have an ability to present antigens to T lymphocytes. …”
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Rapid Destruction of the Humeral Head Caused by Subchondral Insufficiency Fracture: A Report of Two Cases by Kenichi Goshima, Katsuhiko Kitaoka, Junsuke Nakase, Hiroyuki Tsuchiya

“…Magnetic resonance imaging showed a bone marrow edema pattern with an associated subchondral low-intensity band, typical of SIF. …”
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Microbiota Associated with Infections of the Jaws by Elerson Gaetti-Jardim, Luis Fernando Landucci, Kathlenn Liezbeth de Oliveira, Iracy Costa, Robson Varlei Ranieri, Ana Cláudia Okamoto, Christiane Marie Schweitzer

“…In some patients, these infections may spread to bone marrow or facial soft tissues, producing severe and life-threatening septic conditions. …”
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Langerhans Cell Sarcoma: A Case Report Demonstrating Morphological and Immunophenotypical Variability within a Single Lesion by Rasika Singh, Charles Edward Keen, Christopher Stone, Patrick Sarsfield

“…Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells which can occur in skin, bone marrow, lymph nodes, spleen, liver, and lung. LCS can present with multiple cutaneous and systemic lesions. …”
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