Herpes simplex virus-2-associated esophagitis in immunocompetent host by Haider A. Naqvi, Sumanthkumar Bandaru, Adrien L. Janvier, Muhammad Nadeem Yousaf

“…An estimated 10–15% of bone marrow transplant patients and up to 20% of AIDS patients may develop HE [8]. …”
Get full text

HSCT-GAVE as a Manifestation of Chronic Graft versus Host Disease: A Case Report and Review of the Existing Literature by Michael J. Grant, Mitchell E. Horwitz

“…The existing literature links GAVE to patients with cirrhosis, scleroderma, bone marrow transplantation, and chronic renal failure among other associations, but its pathophysiology remains ill-defined. …”
Get full text

Myelodysplastic Syndrome with Transfusion Dependence Treated with Venetoclax by Waqas Jehangir, Alexander Karabachev, Taimoor Jahangir, Elvira Umyarova

“…Myelodysplastic syndromes are characterized by ineffective hematopoiesis in one or more lineages of the bone marrow. They are a group of heterogeneous clonal stem cell malignancies with a high risk to progress to acute myeloid leukemia. …”
Get full text

Pompe Disease Could Mimic Exam Findings of Amyloidosis: Two Rare Diagnoses Bona Fide by Jithma P. Abeykoon, Narjust Duma, Jennifer A. Tracy, Margherita Milone, Ronald Go

“…Given the classic physical finding of macroglossia, the patient underwent extensive evaluation for amyloidosis which proved to be negative apart from a bone marrow biopsy which stained positive for transthyretin without amino acid sequence abnormality, thus giving wild-type transthyretin amyloidosis. …”
Get full text

Comparative Intracellular Cytokine Production by In Vitro Stimulated T Lymphocytes from Human Umbilical Cord Blood (HUCB) and Adult Peripheral Blood (APB) by J. A. García Vela, I. Delgado, R. Bornstein, B. Alvarez, M. C. Auray, I. Martin, F. Oña, F. Gilsanz

“…It has been suggested that there is a reduced graft‐versus‐host‐disease (GVHD) with HUCB compared to bone marrow transplantation. Since cytokine production by a cell is an indication of the cells function it is important to determinate the differences between APB and HUCB with respect to production of these soluble factors. …”
Get full text

Fatal Idiopathic Hyperammonemia after Induction Chemotherapy for Acute Myeloid Leukemia by Christophe Angelo, Marie-Françoise Vincent, Mina Komuta, Philippe Hantson, Nicole Straetmans, Edwige Boulet

“…Idiopathic hyperammonemia is a rare but potentially fatal complication occurring in patients with acute leukemia or bone marrow transplantation. The role of some specific anticancer drugs may be discussed, but the etiology of hyperammonemia is often multifactorial. …”
Get full text

Prognostic Factors and Outcome of Patients with Adult Acute Lymphoblastic Leukemia Treated with the Hyper-CVAD Regimen: A Retrospective Study by Zahra Malakoutikhah, Farzaneh Ashrafi, Ali Derakhshandeh

“…The CR rate had statistical differences by bone marrow transplantation (BMT) and WBC count. The 2-year LFS and OS were 40% and 42%, respectively. …”
Get full text

A review on the potential of Bruton’s tyrosine kinase (Btk) inhibitor – Ibrutinib for treatment of Multiple Myeloma (MM) by Sze-Ting Bong, Lydia Ngiik-Shiew Law, Jodi Woan-Fei Law

“… Multiple myeloma (MM) is characterized by the over-production of monoclonal plasma cells that eventually become malignant in the bone marrow. MM remains as an incurable cancer, but it can be treated through chemotherapy. …”
Get full text

Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature within the Process of Vascular Remodeling: Cellular Basis, Clinical Relevance, and Implications for Stem Cell Th... by Diana Klein

“…Until some years ago, the bone marrow and the endothelial cell compartment lining the vessel lumen (subendothelial space) were thought to be the only sources providing vascular progenitor cells. …”
Get full text

Cellular therapy for the peripheral arterial disease treatment: Protocol for a systematic review and meta-analysis. by Mónica Rodríguez-Valiente, Cristina Fuente-Mora, Javier Sánchez-Gálvez, Micaela Ortín-Pérez, Manuel Pardo-Ríos, José Manuel Sánchez-Sáez, Isac Davidson Santiago Fernandes Pimenta, Grasiela Piuvezam, Laura Ramos-Petersen

“…Many studies have proposed the use of stem cells, such as mesenchymal stem cells, or even mononuclear cells isolated from peripheral blood or bone marrow, to treat PAD. This paper reports a protocol of systematic review and meta-analysis that aims to identify the effects of stem cell treatment in patients with peripheral arterial disease. …”
Get full text

THE RADIATION DOSE PROFILE IN PEDIATRIC INTERVENTIONAL CARDIOLOGY TO ESTIMATE THE STOCHASTIC EFFECT RISK: PRELIMINARY STUDY by Lailatul Muqmiroh, Soegardo Indra Praptono, Rusmanto Rusmanto, Risalatul Latifah, nggraini Dwi Sensusiati

“…Result: The results showed that the greatest exposure was received around vertebrae (bone marrow) because of the superimpose X-ray on the vertebrae during the procedures. …”
Get full text

A Case of a Nonpetrous Cholesterol Granuloma Presenting as a Temporal Mass by Nathaniel Reeve, Jacob Kahane, Matthew Ng

“…This case supports the theory of pathogenesis of such lesions typically occurring where pneumatized air spaces interface with bone marrow, in this case, where the reaches of pneumatized cells in the squamous portion of the temporal bone meet diploic bone.…”
Get full text

Cerebral vein thrombosis as the initial presentation of acute promyelocytic leukemia (APML) by Fizza Zulfiqar, Noora Khadoori, Lisa Deptula, Geetha Krishnamoorthy

“…Her complete blood count showed mild pancytopenia, with normal peripheral smear. She had a normal bone marrow biopsy done due to leukocytosis a year ago. …”
Get full text

Osteopetrosis and Its Relevance for the Discovery of New Functions Associated with the Skeleton by Amélie E. Coudert, Marie-Christine de Vernejoul, Maurizio Muraca, Andrea Del Fattore

“…In particular, the interplay of bone with the stomach, insulin metabolism, male fertility, the immune system, bone marrow, and fat is described.…”
Get full text

Pitfalls in the Diagnosis of Anaplastic Large Cell Lymphoma with a Small Cell Pattern by Rowan L. Grigoropoulos, Penny Wright, Mars B. van t'Veer, Mike A. Scott, George A. Follows

“…In this report, we describe our diagnostic work-up for one such case using blood, lymph node, and bone marrow aspirate samples, highlighting the variability of antigen expression seen in different sample types and methodologies. …”
Get full text

Monoclonal Gammopathy of Renal Significance with Deposits of Peculiar Morphology and Injuries of Secondary Thrombotic Microangiopathy: A Case Report and Review of the Literature by José C. De La Flor, Marina Alonso, Edna Sandoval, Alexander Marschall, Miguel Rodeles

“…We present the case of an 82-year-old woman diagnosed with monoclonal gammopathy of renal significance (MGRS) with the presence of different and peculiar kidney lesions, who began treatment with bortezomib and dexamethasone, presenting during her evolution a relapse. Although the bone marrow biopsy in this case showed plasma cells as pathologic clone and there was also a reduction after chemotherapeutic treatment, rituximab was proposed as a second line. …”
Get full text

Diagnosis of Fanconi Anemia: Chromosomal Breakage Analysis by Anneke B. Oostra, Aggie W. M. Nieuwint, Hans Joenje, Johan P. de Winter

“…Fanconi anemia (FA) is a rare inherited syndrome with diverse clinical symptoms including developmental defects, short stature, bone marrow failure, and a high risk of malignancies. …”
Get full text

Simultaneous Manifestation of Chronic Myelomonocytic Leukemia and Multiple Myeloma during Treatment by Prednisolone and Eltrombopag for Immune-Mediated Thrombocytopenic Purpura by Masao Hagihara, Morihiro Inoue, Kenichiro Kodama, Tomoyuki Uchida, Jian Hua

“…Four years later, there was a prominent increase of peripheral blood monocytes, which was accompanied by recurrence of thrombocytopenia. Bone marrow aspirates and serum electrophoresis revealed coexistence of chronic myelomonocytic leukemia (CMML) and multiple myeloma (MM). …”
Get full text

Treatment of Coexisting Chronic Neutrophilic Leukemia and Light Chain Multiple Myeloma with Hydroxyurea, Bortezomib, and Dexamethasone by Evelyn Taiwo, Huiying Wang, Robert Lewis

“…Peripheral blood flow cytometry was unremarkable without any evidence of lymphoproliferative disorder or myeloblasts. Bone marrow aspiration and biopsy revealed a markedly hypercellular marrow with myeloid lineage predominance and approximately 10% plasma cells. …”
Get full text

Apigenin inhibits NLRP3 inflammasome activation in monocytes and macrophages independently of CD38 by Knut Husø Lauritzen, Knut Husø Lauritzen, Kuan Yang, Michael Frisk, Mieke C. Louwe, Maria Belland Olsen, Maria Belland Olsen, Mathias Ziegler, William E. Louch, Bente Halvorsen, Bente Halvorsen, Pål Aukrust, Pål Aukrust, Arne Yndestad, Øystein Sandanger, Øystein Sandanger

“…However, the NLRP3 inflammasome is not compromised in CD38-/- bone marrow-derived macrophages compared to corresponding WT cells, and apigenin moderated IL-1β release in both genotypes. …”
Get full text