Skeletal Muscle-Derived Stem/Progenitor Cells: A Potential Strategy for the Treatment of Acute Kidney Injury by Egle Pavyde, Romaldas Maciulaitis, Mykolas Mauricas, Gintaras Sudzius, Ernesta Ivanauskaite Didziokiene, Arvydas Laurinavicius, Neringa Sutkeviciene, Edgaras Stankevicius, Justinas Maciulaitis, Arvydas Usas

“…We aimed to characterize rat MDSPCs, compare them with bone marrow mesenchymal stem cells (BM-MSCs), and evaluate the feasibility of MDSPCs therapy for gentamicin-induced AKI in rats. …”
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Ewing sarcoma – pathomechanisms, standard treatment and new therapeutic perspectives by Wojciech Zezuliński, Filip Woliński, Julia Zyśk, Mateusz Korga, Jakub Klas, Jacek Baj, Eliasz Dzierżyński

“… Introduction: Ewing sarcoma is the second most common bone tumor among children, and due to its high malignancy 5-year survival rate for patients with primary lesions is around 70%. …”
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Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans demonstrates widespread interaction and a function in collagen secretion by Mehul Vora, Jonathan Dietz, Zachary Wing, Karen George, Jun Kelly Liu, Christopher Rongo, Cathy Savage-Dunn

“…Smads and their transcription factor partners mediate the transcriptional responses of target cells to secreted ligands of the transforming growth factor-β (TGF-β) family, including those of the conserved bone morphogenetic protein (BMP) family, yet only a small number of direct target genes have been well characterized. …”
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Enhancing oncology patient care: nurses’ knowledge, attitudes, and perceived benefits of early palliative integration - a cross-sectional study by Mohammed F. Hayek, Bahaaeddin M. Hammad, Faeda A. Eqtait, Ahmad Ayed, Basma Salameh, Nizar B. Said, Rasha S. Abu Zaitoun, Shurouq G. Qadous

“…Data were collected using paper based self-administered questionnaires from nurses working in hematology, general oncology, and bone marrow transplantation departments. Results Among of 128 nurses, the study revealed a moderate level of knowledge (3.64 ± 0.96), Positive attitude (3.59 ± 1.02) and moderately recognized the perceived benefits of early palliative care (3.57 ± 1.02). …”
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Clinical Efficacy of Three-Dimensional-Printed Pure Titanium Fracture Plates with Locking Screw Systems in Distal Tibia Fractures by Ji Hye Choi, Jun Hyoung Lee, Seung Hyeop Lee, Woo Young Jang

“…<i>Background and Objectives:</i> Distal tibia fractures are high-energy injuries characterized by a mismatch between standard plate designs and the patient’s specific anatomical bone structure, which can lead to severe soft tissue damage. …”
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Mesenchymal Stromal Cells Accelerate Epithelial Tight Junction Assembly via the AMP-Activated Protein Kinase Pathway, Independently of Liver Kinase B1 by P. Rowart, P. Erpicum, J.-M. Krzesinski, M. Sebbagh, F. Jouret

“…The in vitro Ca2+ switch from 5 μM to 1.8 mM was performed using epithelial Madin-Darby canine kidney (MDCK) cells cultured alone or cocultured with rat bone marrow-derived MSC or preexposed to MSC-conditioned medium. …”
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The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice by Vasiliy V. Kurilin, Julia N. Khantakova, Valeriy P. Tereschenko, Julia A. Lopatnikova, Irina A. Obleukhova, Sergey V. Sennikov

“…DCs were derived from bone marrow cells in the presence of rmGM-CSF and rmIL-4. …”
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Effectively alleviate rheumatoid arthritis via maintaining redox balance, inducing macrophage repolarization and restoring homeostasis of fibroblast-like synoviocytes by metformin-... by Rui Zhang, Xingyu Lin, Rongjie Lin, Zhenbin Chen, Chenfang Miao, Yao Wang, Xiaoqin Deng, Jianlong Lin, Shishui Lin, Shaohuang Weng, Min Chen

“…In vivo therapeutic investigation suggested that MCDs reduced synovial inflammation and hyperplasia, ultimately prevented cartilage destruction, bone erosion, and synovial fibrosis in CIA rats. …”
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Biomechanical Impact of Vertebral Augmentation Techniques: Clinical and Radiological Results in the Literature by Eliodoro Faiella, Federica Vaccarino, Domiziana Santucci, Elva Vergantino, Bruno Beomonte Zobel, Rosario Francesco Grasso

“…Furthermore, preclinical studies indicate that third-generation devices like SpineJack^® enhance vertebral height restoration and stability, with performance influenced by bone quality and implant positioning, and have demonstrated superior initial and sustained height maintenance compared to kyphoplasty. …”
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Osteoarthritis-like changes in rat temporomandibular joint induced by unilateral anterior large overjet treatment by Xinru Xie, Rui Chao, Yi Mao, Tianhao Wan, Yexin Wang, Yan Zhu, Weifeng Xu, Xuzhuo Chen, Yong Wang, Zhigui Ma, Shanyong Zhang

“…By inducing a posteriorly positioned condyle, the UALO device effectively results in cartilage degradation, subchondral bone loss, condylar volume reduction, and mandibular retrusion. …”
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Association of patellofemoral osteoarthritis on patient-reported outcomes after medial unicompartmental knee arthroplasty: a retrospective cohort study by Jonathan Winther Olsen, Christian Bredgaard Jensen, Kristine Ifigenia Bunyoz, Anders Flygenring Bagge, Kirill Gromov, Anders Troelsen

“…PFOA was graded intraoperatively as 0 = normal cartilage, 1–2 = superficial changes or < 50% of depth, and 3–4 = changes of > 50% of depth or to the bone, using the International Cartilage Repair Society (ICRS) cartilage lesion classification system. …”
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AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription by Lingshan Zhou, Yuan Yang, Qian Qiao, Yingying Mi, Yuling Gan, Ya Zheng, Yuping Wang, Min Liu, Yongning Zhou

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Does Adiponectin Act as an Antiangiogenic Factor in B-Cell Chronic Lymphocytic Leukemia? by Stefano Molica, Giovanna Digiesi, Angelo Vacca, Rosanna Mirabelli, Katia Todoerti, Caterina Battaglia, Fortunato Morabito, Antonino Neri, Domenico Ribatti

“…In this study, we assessed serum levels of adiponectin in 69 patients with Binet stage A B-CLL, and these values were retrospectively correlated with bone marrow (BM) microvessel area and serum levels of vascular endothelial growth factor (VEGF), fibroblast growth factor-2 (FGF-2), angiogenin, PECAM-1 (CD31), matrix metalloproteinase-9 (MMP-9), interleukin-8 (IL-8), syndecan-1, and the percentage of CD38+ or ZAP-70+ CLL cells. …”
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麝香组分诱导成年大鼠骨髓间质干细胞体外定向分化为神经元样细胞的能力 by 肖庆忠, 李浩威, 黄少华

“…收稿日期:2002 -08 -18 　　　　摘　要:【目的】探讨麝香组分体外诱导成年大鼠骨髓间质干细胞(adult rat bone marrow mesenchymal stem cells , rBMMSCs) 定向分化为神经元样细胞的能力。…”
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Social media-based Health Education plus Exercise Program (SHEEP) to improve muscle function among young-old adults with possible sarcopenia in the community: A feasibility study p... by Ya Shi, Emma Stanmore, Lisa McGarrigle, Chris Todd

“…The secondary outcome is to compare standard measures for muscle function (e.g. handgrip strength, skeletal muscle mass, physical performance), body composition (e.g. body fat, body mass index, bone mineral), and other measures (e.g. perceived knowledge, personal motivation, behavioral skills). …”
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PI3Kδ inhibitor linperlisib combined with gemcitabine and oxaliplatin for relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase Ib/II trial by Peng Sun, Hong Cen, Haiyan Yang, Rui Huang, Zhen Cai, Xuekui Gu, Hanying Bao, Zusheng Xu, Zuhong Xu, Zhi-Ming Li

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Morphological analysis of sigmoid sinus anatomy: clinical applications to neurotological surgery by Kylen Van Osch, Daniel Allen, Bradley Gare, Thomas J. Hudson, Hanif Ladak, Sumit K. Agrawal

“…Results Three-dimensional models from 38 temporal bones were generated and analyzed. Right dominance was observed in 74% of the paired SSs. …”
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Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study by Isabel Omaña-Guzmán, Ashuin Kammar-García, Luis Miguel Gutierrez-Robledo, Oscar Rosas-Carrasco

“…On the other hand, obesity has been associated with osteosarcopenia, and several biological mechanisms in the relationship between muscle, bone, and fat have been identified. However, in both cases, there is a lack of longitudinal studies that allow evaluation of whether these conditions precede and increase the risk of osteosarcopenia. …”
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Transcriptional activity of repair, apoptosis and cell cycle genes (TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) in chronically exposed perso... by V. S. Nikiforov, E. A. Blinova, A. I. Kotikova, A. V. Akleyev

“…The mean accumulated dose to red bone marrow was 426.4±48.2 mGy (1.3–2930.0 mGy), to thymus and peripheral immune organs, 58.9±7.9 mGy (0.1–489.0 mGy). …”
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BMP4 Cooperates with Retinoic Acid to Induce the Expression of Differentiation Markers in Cultured Mouse Spermatogonia by Yongguang Yang, Yanmin Feng, Xue Feng, Shangying Liao, Xiuxia Wang, Haiyun Gan, Lixian Wang, Xiwen Lin, Chunsheng Han

“…Using this culture system, the expression and function of bone morphogenetic protein 4 (BMP4) were explored. …”
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