Influence of sacroiliac joint variation on clinical features of axial spondyloarthritis: a comparative analysis by Denis Poddubnyy, Torsten Diekhoff, Sevtap Tugce Ulas, Fabian Proft, Valeria Rios Rodriguez, Judith Rademacher, Juliane Greese, Katharina Ziegeler, Carolina Dominguez Aleixo, Maximilian Lindholz

“…Objectives Anatomical variation of the sacroiliac (SI) joints is common and specific variants are associated with erosions and bone marrow oedema on imaging. Our investigation aims to evaluate whether anatomical variations influence the clinical presentation of axial spondyloarthritis (axSpA).Methods In this propensity score matched post hoc analysis documented clinical data from four prospective clinical cohorts was assessed. …”
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miR-223-3p Inhibits Antigen Endocytosis and Presentation and Promotes the Tolerogenic Potential of Dendritic Cells through Targeting Mannose Receptor Signaling and Rhob by Hao-Cheng Tang, Yin-Yan Lai, Jing Zheng, Hong-Yan Jiang, Geng Xu

“…FITC-OVA antigen uptake and cell surface markers in bone marrow-derived DCs (BMDCs) were analyzed by flow cytometry. …”
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STUDY OF THE EFFECT OF METHIONINE HYPERHOMOCYSTEINEMIA AND ITS CORRECTION WITH CHOLINE AND VITAMIN D ON THE CONDITION OF THE PERIODONTIUM, SMALL INTESTINE, AND LIVER OF RATS by Oleh Kutelmakh, Yulia Chumakova, Lina Kovalchuk, Yulia Odnorih, Olexandra Kutelmakh, Anastasiya Spodaruk

“…Increased excretion of calcium from the body of rats with urine indicates a violation of bone metabolism, which may be a consequence of calcium deficiency in animals with hyperhomo-cysteinemia. …”
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Mesenchymal Stem Cells from Patients with Rheumatoid Arthritis Display Impaired Function in Inhibiting Th17 Cells by Yue Sun, Wei Deng, Linyu Geng, Lu Zhang, Rui Liu, Weiwei Chen, Genhong Yao, Huayong Zhang, Xuebing Feng, Xiang Gao, Lingyun Sun

“…This study explored the function of bone marrow MSCs from rheumatoid arthritis (RA) patients, focusing on immunomodulatory effects. …”
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Tibiofemoral Joint Contact Force Estimation Based on OpenSim Musculoskeletal Modeling by WANG Xiaoling, JIAN Jiawei, XIE Qiurong, LIAN Zhanghui, GUO Chunming, GUO Jiemei, LI Yurong

“…Compared with the imimplanted pressure testing equipment, the tibiofemoral joint contact force estimation method based on OpenSim muscle bone modeling could accurately predict the medical, lateral and total contact forces of the knee joint.ConclusionThe established full-body OpenSim musculoskeletal model of the knee joint with two contact points and three degrees of freedom can be used to generate muscle-driven gait simulation and obtain reliable contact forces of the tibiofemoral joint, which provides an important basis for accurate monitoring of tibiofemoral joint load, formulation of clinical rehabilitation programs and continuous improvement of prosthesis design.…”
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Differential effects of structurally different lysophosphatidylethanolamine species on proliferation and differentiation in pre-osteoblast MC3T3-E1 cells by Fumiaki Makiyama, Shiori Kawase, Aoi William Omi, Yusuke Tanikawa, Taishi Kotani, Teruki Shirayama, Naoyuki Nishimura, Taiga Kurihara, Naoto Saito, Jun Takahashi, Takeshi Uemura

“…These results suggest the physiological significance of LPEs in bone formation and indicate that different LPE species and their receptors play distinctive roles in this process.…”
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A ten-year evaluation of central nervous system cystic echinococcosis in a highly endemic area of Iran: Molecular epidemiology and clinicopathological characteristics by Mohsen Najjari, Ali Dehesht Manesh, Shahab Rezaeian, Bibi Razieh Hosseini Farrash, Mohammad Ali Mohammadi, Mohammad Ebrahimipour

“…Spine infections included bone cartilage, ligaments, and hydatid cyst wall fragments. …”
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A case of 49,XXXYY followed-up from infancy to adulthood with review of literature by Junko Kanno, Akinobu Miura, Sayaka Kawashima, Hirohito Shima, Dai Suzuki, Miki Kamimura, Ikuma Fujiwara, Masayuki Kamimura, Mitsugu Uematsu, Masataka Kudo, Atsuo Kikuchi

“…He has maintained normal lipid and glucose metabolism, as well as bone density, for a prolonged period. There are no other reports on the long-term effects of testosterone treatment for the SCA. …”
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Multimodality Imaging Probe for Positron Emission Tomography and Fluorescence Imaging Studies by Suresh K. Pandey, Jasmeet Kaur, Balu Easwaramoorthy, Ankur Shah, Robert Coleman, Jogeshwar Mukherjee

“…The same mouse was then placed under an Inveon microPET scanner (Siemens Medical Solutions, Knoxville, TN) injected (intravenously) with 25 μCi of 18 F and after a half-hour (to allow sufficient bone uptake) was imaged for 30 minutes. Molecular weight determined using matrix-associated laser desorption ionization (MALDI) for the BSA sample was 66,485 Da and for biotin-BSA was 67,116 Da, indicating two biotin moieties per BSA molecule; for biotin-BSA-DTPA was 81,584 Da, indicating an average of 30 DTPA moieties per BSA molecule; and for FAM conjugate was 82,383 Da, indicating an average of 1.7 fluorescent moieties per BSA molecule. …”
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Successful Neurological Recovery with Multimodality Therapy without Surgery for Spinal Metastases from Advanced Gastric Cancer by Hideyuki Kinoshita, Hiroto Kamoda, Takeshi Ishii, Yoko Hagiwara, Toshinori Tsukanishi, Yusuke Amanuma, Rino Nankinzan, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Tsukasa Yonemoto

“…Advanced gastric cancer with bone metastasis has a very poor prognosis with short median survival. …”
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Characterization of a New Immunosuppressive and Antimicrobial Peptide, DRS-DA2, Isolated from the Mexican Frog, Pachymedusa dacnicolor by Claire Lacombe, Estefania Aleman-Navaro, Thierry Drujon, Veronica Martinez-Osorio, Emmanuelle Sachon, Erika Melchy-Pérez, Ludovic Carlier, Lorena Elizabeth Fajardo Brigido, Yannick Fleury, Christophe Piesse, Guadalupe Gutiérrez-Escobedo, Alejandro De las Peñas, Irene Castaño, Florie Desriac, Jose Luis Beristain-Hernandez, Christophe Combadiere, Yvonne Rosenstein, Constance Auvynet

“…After the induction of peritonitis, a local injection of DRS-DA2N could decrease the number of inflammatory cells locally in the peritoneal cavity without inducing a systemic effect, as no changes in the number of inflammatory cells could be detected in blood or in the bone marrow. Collectively, these data suggest that this peptide could be a promising tool in the treatment of inflammatory diseases, such as inflammatory skin diseases, as it could reduce the number of inflammatory cells locally without suppressing the ability to combat infections.…”
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A Case of Nonfunctioning Pituitary Carcinoma That Responded to Temozolomide Treatment by Haruko Morokuma, Takao Ando, Takuya Hayashida, Ichiro Horie, Naoko Inoshita, Fumi Murata, Ikuko Ueki, Kan Nakamura, Misa Imaizumi, Toshiro Usa, Atsushi Kawakami

“…The pituitary carcinoma was accompanied by meningeal dissemination with cerebral and L1 spinal bone metastasis. The patient received continuous dosing of TMZ along with external radiation, followed by standard dosing of TMZ. …”
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Mechanisms of Hearing Loss in a Guinea Pig Model of Superior Semicircular Canal Dehiscence by Bu-Sheng Tong, Zi-Yu He, Chen-Ru Ding, Juan-Mei Yang, Jing Wang, Zhao Han, Yi-Bo Huang, Na Gao, Xian-Hao Jia, Fang-Lu Chi, Dong-Dong Ren

“…Among them, semicircular canal dehiscence (SCD) with a defective semicircular bone is typical. Currently, the pathogenesis of SCD is usually explained by the third window hypothesis; however, this hypothesis fails to explain the variability in the symptoms and signs experienced by superior SCD (SSCD) patients. …”
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MiR-181a-5p Delivered by Adipose-Derived Mesenchymal Stem Cell Exosomes Alleviates Klebsiella pneumonia Infection-Induced Lung Injury by Targeting STAT3 Signaling by Ren-Jing Hu, Xiao-Chun Chen, Lei Xu, Xiao-Hong Rui, Lin Wan, Jie Lu, Jun Liu, Hao Pei

“…The translocation of ADSC-derived exosomes to bone marrow-derived macrophages (BMDMs) was detected. …”
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Bleeding control of an injury to the infrarenal inferior vena cava and right external iliac vein by ipsilateral internal iliac artery and superficial femoral vein ligation after bl... by Hoonsung Park, Maru Kim, Dae-Sang Lee, Tae Hwa Hong, Doo-Hun Kim, Hangjoo Cho

“…Injuries to the right side of the infrarenal IVC and the right external iliac vein (EIV) were suspected, along with fractures to the right iliac bone and sacrum. The injury to the right side of the infrarenal IVC wall was repaired, and the right internal iliac artery was ligated. …”
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Optimization of In Vivo Studies by Combining Planar Dynamic and Tomographic Imaging: Workflow Evaluation on a Superparamagnetic Nanoparticles System by Maritina Rouchota, Alessio Adamiano, Michele Iafisco, Eirini Fragogeorgi, Irineos Pilatis, Gilles Doumont, Sébastien Boutry, Daniele Catalucci, Argyro Zacharioudaki, George C. Kagadis

“…Molecular imaging holds great promise in the noninvasive monitoring of several diseases with nanoparticles (NPs) being considered an efficient imaging tool for cancer, central nervous system, and heart- or bone-related diseases and for disorders of the mononuclear phagocytic system (MPS). …”
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Evaluation and diagnostic approach in patient with Perrault Syndrome by Rachael Christin Nathania, Steven Yulius Usman, Ekarini Aryasatiani

“…Symptomatic treatment included bone conduction hearing aids and estrogen replacement therapy. …”
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Anterior skull base reconstruction using nasoseptal flap: cadaveric feasibility study and clinical implication [SevEN-001] by Kyoung Su Sung, Jaejoon Lim, Minkyun Na, Sanghun Lee, Ju-Seong Kim, Je Beom Hong, Chang-Ki Hong, Ju Hyung Moon

“…After the sphenoidotomy, the length by which the PNSF fell short in providing coverage at the posterior wall of the frontal sinus (CPFS), and the extent of the anterior coverage from the limbus (CL) of the sphenoid bone was measured. Results Without sphenoidotomy, the mean length of the remaining PNSF after the coverage of the posterior wall of the frontal sinus was 0.67 cm. …”
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Progress in Study of Low-Intensity Pulsed Ultrasound Acting on Inflammation-Related Signaling Pathways in Knee Osteoarthritis by OUYANG Hui, LIN Xingjin, WANG Jinying, SHEN Longbin, WANG Chengdong

“…Knee osteoarthritis (KOA) is a degenerative total joint disease involving pathological changes in the cartilage, synovium, subchondral bone, and periarticular ligaments and muscles of the joint. …”
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Nosemosis negatively affects honeybee survival: experimental and meta-analytic evidence by Monika Ostap-Chec, Jessica Cait, R. Wilder Scott, Aneta Arct, Dawid Moroń, Marcin Rapacz, Krzysztof Miler

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