-
361
A physiologically-based pharmacokinetic model for the antibiotic ertapenem
Published 2015-09-01“…PBPK modeling incorporates known physiological parameters such as body weight, organ volumes, and blood flow rates in particular tissues. Furthermore, ertapenem is highly bound in human blood plasma; therefore, nonlinear binding is incorporated in the model since only the free portion of the drug can saturate tissues and, hence, is the only portion of the drug considered to be medicinally effective. …”
Get full text
Article -
362
Effects of Carbon Dioxide Therapy on Skin Wound Healing
Published 2025-01-01“…The main effects of CO<sub>2</sub> therapy described were as follows: improved blood flow and local oxygenation, reduction of the inflammatory process, increased collagen production, and improved clinical aspects of wounds, with faster healing. …”
Get full text
Article -
363
Post-COVID effect on heart after recovery based on hybrid EfficientNet-DBN with multilevel classification using ECG images
Published 2024-09-01“…Such heart issues involve irregular heartbeats, heart failure, which is the inability of the heart to pump correctly, and coronary disease, which builds up in the arteries and causes restriction in blood flow, heart attacks, etc. Therefore, classifying this disease at an early stage is crucial. …”
Get full text
Article -
364
Alterations of the Erythrocyte Membrane during Sepsis
Published 2012-01-01“…An understanding of the mechanisms of RBC rheologic alterations in sepsis and their effects on blood flow and on oxygen transport may be important to help reduce morbidity and mortality from severe sepsis.…”
Get full text
Article -
365
A Case of Vaginal Stillbirth in the Presence of Placenta Previa at 33 Weeks of Gestation
Published 2016-01-01“…Although further studies to confirm the dynamic change of the uteroplacental blood flow are necessary to avoid the risk of maternal hemorrhage, vaginal TOP with placenta previa after feticide or IUFD would be feasible.…”
Get full text
Article -
366
ntPET: A New Application of PET Imaging for Characterizing the Kinetics of Endogenous Neurotransmitter Release
Published 2005-10-01“…The accuracy and precision of the method—as well as its potential for false-positive responses due to noise or changes in blood flow—were examined. Finally, we applied the ntPET method to small-animal imaging data in order to produce the first noninvasive assay of the time-varying release of dopamine in the rat striatum following alcohol.…”
Get full text
Article -
367
Effect of electroacupuncture on vascular remodeling in rats with cerebral ischemia by regulating irisin based on VEGF/Akt/eNOS signaling pathway
Published 2025-02-01“…Neurobehavioral function was evaluated using 2,3,5-triphenyltetrazolium chloride (TTC) staining and behavioral experiments, while vascular remodeling was evaluated using laser speckle blood flow imaging, and the expressions of irisin and vascular remodeling-related factors were measured by ELISA and Western blotting. …”
Get full text
Article -
368
Nasal hyperreactivity and inflammation in allergic rhinitis
Published 1996-01-01“…The histopathological features of allergic inflammation involve an increase in blood flow and vascular permeability, leading to plasma exudation and the formation of oedema. …”
Get full text
Article -
369
Chronic Expanding Hematoma in the Popliteal Fossa after Pseudoaneurysm Surgery because of Nail Puncture
Published 2014-01-01“…On the arteriography, the popliteal artery was occluded and the blood flow was maintained with collateral vessels. On MRI, an enormous swelling of 115 × 107 × 196 cm in diameter was seen. …”
Get full text
Article -
370
Clinical case of treatment of subacute endocarditis in a patient after occluder closing of the patent foramen ovale
Published 2021-07-01“…Transesophageal echocardiography showed no residual blood flow through the interatrial septum. The postoperative period was uneventful. …”
Get full text
Article -
371
Flow-Mediated Dilatation: Learning Curve Study with a Novice Operator
Published 2024-08-01“…Duplex ultrasound was used for the simultaneous and continuous measurement of brachial artery diameter and local blood flow velocity. Following a 1-min recording of baseline diameter (D), FMD was measured after a 5-min period of occlusion of the proximal forearm vessels. …”
Get full text
Article -
372
Protective Role of Platelets in Myocardial Infarction and Ischemia/Reperfusion Injury
Published 2021-01-01“…The standard therapy for ischemia is revascularization and restoration of blood flow to previously ischemic myocardium. Paradoxically, reperfusion may result in further tissue damage called ischemia/reperfusion injury (IRI). …”
Get full text
Article -
373
Emergency Pancreatoduodenectomy with Preservation of Gastroduodenal Artery for Massive Gastrointestinal Bleeding due to Duodenal Metastasis by Clear Cell Renal Cell Carcinoma in a...
Published 2014-01-01“…The patient had an uneventful recovery and did not experience further bleeding. Also the blood flow to the liver was compromised as shown by the normal liver function tests (LFTs) postoperatively. …”
Get full text
Article -
374
Pharmacokinetic, Pharmacogenetic, and Other Factors Influencing CNS Penetration of Antiretrovirals
Published 2016-01-01“…Other factors are related to pharmacokinetics and pharmacogenetics of the specific ARV agent or mediated by drug interactions, local inflammation, and blood flow. In this review, we provide an overview of the various factors influencing CNS penetration of ARV drugs with an emphasis on those commonly used in sub-Saharan Africa. …”
Get full text
Article -
375
Brain Multimodality Monitoring: A New Tool in Neurocritical Care of Comatose Patients
Published 2017-01-01“…These tools include intracranial pressure (ICP) monitors, transcranial Doppler (TCD), Hemedex™ (thermal diffusion probe used to measure regional cerebral blood flow), microdialysis catheter (used to measure cerebral metabolism), Licox™ (probe used to measure regional brain tissue oxygen tension), and continuous electroencephalography. …”
Get full text
Article -
376
The Effectiveness of ROMATIF Therapy (Mirror Therapy and Positive Affirmation) on Strength of Muscle and Self-acceptance in Post Stroke Patients
Published 2025-01-01“… Introduction: Stroke is a neurological condition in which some brain cells die due to a disruption of cerebral blood flow caused by a blockage or rupture of blood vessels. …”
Get full text
Article -
377
3D Segmentation and Visualization of Skin Vasculature Using Line-Field Confocal Optical Coherence Tomography
Published 2024-12-01“…These visualizations provide insights into vessel morphology, spatial arrangements, and blood flow patterns, which are crucial for assessing tumor growth and potential therapeutic responses. …”
Get full text
Article -
378
Alterations in cerebral perfusion and corresponding brain functional networks in systemic lupus erythematosus with cognitive impairment
Published 2025-01-01“…Seed-based functional connectivity (FC) was calculated using the cerebral blood flow (CBF) results. Compared with SLE-NC, patients with SLE-CI had higher CBF in the left hippocampus, thalamus, and cerebellum crus II and lower CBF in the left frontal lobe. …”
Get full text
Article -
379
Laparoscopic Adnexal Detorsion in a 20-Week Pregnant Patient: A Case Report and Literature Review
Published 2019-01-01“…Adnexal torsion occurs when there is a complete turn of the ovary, tube, or both resulting in impaired blood flow to the ovary. The diagnosis of adnexal torsion is sometimes challenging due to the enlarged effect of the uterus, the displacement of abdominal and pelvic structures and the nonspecific symptoms in pregnancy. …”
Get full text
Article -
380
Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
Published 2025-02-01“…Abstract Background Angiotensin-Converting Enzyme 2 (ACE2) is a crucial peptidase in human peptide hormone signaling, catalyzing the conversion of Angiotensin-II to Angiotensin-(1–7), which activates the Mas receptor and elicits vasodilation, increased blood flow, reduced inflammation, and decreased pathological tissue remodeling. …”
Get full text
Article