No correlation between thrombin generation and emicizumab levels: implications for monitoring emicizumab therapy by Konrad van der Zwet, Mark Roest, Dana Huskens, Roger E.G. Schutgens, Lize F.D. van Vulpen, Kathelijn Fischer, Rolf T. Urbanus

“…Results: Eighty-five samples from 49 patients were analyzed during a median of 1 year of emicizumab therapy. Most bleeds were traumatic (97%; n = 30), whereas 1 bleed was spontaneous. …”
Get full text

Perinephric Hematoma with Active Arterial Hemorrhage following Extracorporeal Shockwave Lithotripsy by Edward Assaf, Rawad Abou Zahr, Elie Ghabi, Imad Ghantous

“…Subcapsular hematoma is an exceedingly rare complication of extracorporeal shockwave lithotripsy (ESWL) for renal stones with cases demonstrating evidence of active arterial bleeding even more so. A 49-year-old male presented with acute onset right flank pain two hours following ESWL. …”
Get full text

A Pilot Study on Forensic Imaging of Mechanical Injuries by Bin Wu, Yang Li, Yang Li, Bin Wu, Xiao-Fei Hu, Zhi-Yuan Xia, Wei Li, Guang-Long He, Jian-Jun Li

“…Methods: Three cases of mechanical injury were collected, and the external examination, postmortem computed tomography (PMCT), postmortem computed tomography angiography (PMCTA), and autopsy examination were performed in proper order to compare and analyze the diagnostic ability of postmortem imaging in the exploration of fractures, organ ruptures, and bleeding sources. Conclusion: Postmortem imaging (PMCT and PMCTA) has important application value in the analysis of cause of death, inference of injury objects, wound reconstruction, and search for bleeding sources. …”
Get full text

Fordyce Angiokeratoma: Comparison of Cryotherapy and Electrocauterization Treatments by Necmi Bayraktar

“…Patient comfort can be defined as pain management during the procedure and the healing period. Bleeding and wound infection are other parameters that may decrease patient comfort. …”
Get full text

A Case Report of Femoral Hematoma following Obturator Nerve Block by Kiyoshi Moriyama, Kumi Moriyama, Tomoki Kohyama, Kunitaro Watanabe, Mieko Chinzei, Tomoko Yorozu

“…We encountered massive bleeding and a huge hematoma after ONB. Case Presentation. …”
Get full text

Gastric necrosis after gastric artery embolization in a patient with blunt abdominal trauma: a case report by Gil Hwan Kim, Sung Jin Park, Chan Ik Park

“…Gastric artery bleeding after blunt trauma is rare. In such cases, if vital signs are stable, angiographic embolization may be performed. …”
Get full text

Recombinant factor VIIa: new insights into the mechanism of action through product innovation by Miguel A. Escobar, Maureane Hoffman, Giancarlo Castaman, Cedric Hermans, Johnny Mahlangu, Johannes Oldenburg, Charles L. Percy, Mark T. Reding, Amy D. Shapiro, Steven W. Pipe

“…Management of bleeding in persons with hemophilia and inhibitors involves treatment with bypassing agents, including recombinant activated factor VII (rFVIIa). …”
Get full text

Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in patients with chronic coronary artery disease (CAD) - current state of knowledge and perspective... by Hubert Bochenek, Anna Bielicka, Michał Bzoma, Julia Gugulska, Irmina Czerepak, Marcin Kapij, Karolina Niewczas, Adrianna Brzozowska

“…While this is effective in reducing thrombotic events, it also increases bleeding risk. Current European Society of Cardiology (ESC) guidelines recommend tailoring DAPT duration and composition based on individual patient risk factors for bleeding and ischemia. …”
Get full text

Edoxaban Monotherapy in Nonvalvular Atrial Fibrillation Patients with Coronary Artery Disease by Daisuke Fukamachi, Yasuo Okumura, Naoya Matsumoto, Eizo Tachibana, Koji Oiwa, Makoto Ichikawa, Hironori Haruta, Kazumiki Nomoto, Ken Arima, Atsushi Hirayama

“…The primary study endpoint was the composite incidence of major bleeding and clinically significant bleeding, defined according to the ISTH criteria. …”
Get full text

Application of S-100 absorbable hemostatic patch in endonasal endoscopic dacryocystorhinostomy: A randomized controlled trial by Hai-Sheng Zheng, Xing-Wu Zhong, Jia-Yao Xu, Hai-Yan Chen, Li-Na Liu, Bo-Wen Ou-Yang

“…The patients were followed up for 12 months, and the mucosal epithelialization of the wound, granulation formation, bleeding, and success rate of ostial patency were compared between the two groups. …”
Get full text

Transfusion in trauma: empiric or guided therapy? by Liam Barrett, Nicola Curry

“…Empiric vs guided” was presented at the International Society on Thrombosis and Haemostasis Congress in 2024. Uncontrolled bleeding is the commonest preventable cause of death after traumatic injury. …”
Get full text

Hemophilia A Haplotypes in Southwestern Iran by Bizhen Keikhaei Dehdezi, Ali Khodadadi, Arta Farhadi Kia, Faezeh Abbasi, Saeed Bitraf, Roya Salehi Kahyesh

“…In 39 patients, the most common bleeding site was in the joints, and only one case had bleeding in the gastrointestinal tract. …”
Get full text

An Unusual Cause of Cardiac Tamponade during Cardiac Catheterization Study by Deepanwita Das, Monalisa Datta, Somnath Dey, Jyotiranjan Parida, Rupesh Kumar, Arindam Pande

“…Usual cause of tamponade after right ventricular perforation is bleeding from the RV, but in our case the second tamponade was not due to bleeding from the RV, but was rather from new laceration injury of epicardial vessels which was remained undiagnosed till exploration.…”
Get full text

Enteroscopic Diagnosis and Management of Small Bowel Diverticular Hemorrhage: A Multicenter Report from the Taiwan Association for the Study of Small Intestinal Diseases by Yang-Yuan Chen, Cheng-Tang Chiu, Chen-Ming Hsu, Tsung-Hsing Chen, Yi-Chun Chiu, Yen-Chang Chu, Chen-Wang Chang, Hsiu-Po Wang, Deng-Chyang Wu, Tien-Yu Huang, Hsu-Heng Yen

“…Small bowel diverticulum is a rare cause of gastrointestinal bleeding. The diagnosis and treatment of small bowel diverticular hemorrhage is clinically challenging before the development of deep enteroscopy. …”
Get full text

THE EFFECT OF TRANEXAMIC ACID INJECTION ON HEMOGLOBIN LEVEL, ALBUMIN LEVEL, AND PAIN ON PATIENT RECEIVING TOTAL KNEE REPLACEMENT by Dwikora Novembri Utomo, Teddy Heri Wardhana, Ahmad Hannan Amrullah, Hamzah Hamzah

“…Total Knee Replacement (TKR) surgery procedure is at risk of massive bleeding. Bleeding can affect albumin levels and the onset of intra-compartment pressure on the nerves. …”
Get full text

The Study of Cost-Effectiveness of Rivaroxaban versus Warfarin in Patients with Atrial Fibrillation Who Developed Ischemic Stroke by Neda Jaberi, Zahra Kavosi, Etrat Hooshmandi, Nasrin Moradi, Khosro Keshavarz, Afshin Borhani-Haghighi

“…The final and clinical (intermediate) outcomes were QALYs and no bleeding and prevention of ischemic stroke, respectively. …”
Get full text

Benefits and Harms of Extending the Duration of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Drug-Eluting Stents: A Meta-Analysis by Chun Shing Kwok, Heerajnarain Bulluck, Alisdair D. Ryding, Yoon K. Loke

“…Pooled results showed a significantly lower risk of major bleeding (RR 0.48 95% CI 0.25–0.93) and total bleeding (RR 0.30 95% CI 0.16–0.54) for shorter compared to longer duration of DAPT. …”
Get full text

A meta-analysis on the impact of concurrent or pre-existing cancer diagnosis on acute myocardial infarction outcomes. by Jie Wang, Jia Yu

“…<h4>Objective</h4>To provide updated evidence on the effect of concomitant or previous cancer diagnoses on mortality and risk of complications, specifically major bleeding, myocardial reinfarction, and stroke, of patients with AMI.…”
Get full text

Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition by Afnan Deebani, Jabila Mary, Sanchi Dhinoja, Ayah Al Qaryoute, Weam Fallatah, Pudur Jagadeeswaran

“…Our RNAseq analysis identified 89 tmem genes in zebrafish thrombocytes, leading to further investigation through knockdown experiments and gill bleeding assays. Knockdown of tmem242 significantly increased bleeding, indicating a role in hemostasis. …”
Get full text

Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient by Amina M. Bagher

“…It can also cause gastrointestinal (GI) bleeding, especially in individuals with a history of GI ulcers or bleeding disorders. …”
Get full text