Promising horizons in achondroplasia along with the development of new drugs by Keiichi Ozono, Takuo Kubota, Toshimi Michigami

“…Along with severe short stature, foramen magnum stenosis and spinal canal stenosis are major complications: the former leads to sleep apnea, breathing disorders, myelopathy, hydrocephalus, and sudden death, and the latter causes pain in the extremities, numbness, muscle weakness, movement disorders, intermittent claudication, and bladder-rectal disorders. Growth hormone treatment is available for ACH only in Japan. …”
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Asymptotic analysis of mathematical model describing a new treatment of breast cancer using AZD9496 and palbociclib by Ophir Nave, Ophir Nave

“…Cancer can start almost anywhere in the human body such as the breast, prostate, colorectal, brain, bones, lungs, bladder etc. The main differences between the different types of cancer are related to the organ in which the tumor develops and the type of cells that compose the tumor.MethodThis paper focused on the breast cancer. …”
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Sexual Satisfaction in Fully Ambulatory People with Multiple Sclerosis: Does Disability Matter? by Pawel Dobrakowski, Agnieszka Machowska-Majchrzak, Beata Labuz-Roszak, Ewa Niewiadomska, Krystyna Pierzchala

“…Secondary SD result from the symptoms that do not directly involve nervous pathways to the genital system, such as bladder and bowel problems, fatigue, spasticity, or muscle weakness. …”
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Posterior Nutcracker Syndrome with Left Renal Vein Duplication: A Rare Cause of Haematuria in a 12-Year-Old Boy by J. Preza Fernandes, Rui Amorim, M. J. Gomes, V. Oliveira, A. Reis, J. Ribeiro-Castro

“…The patient was initially hospitalized and managed with oral iron supplements and continuous saline bladder irrigation, not requiring additional treatment. …”
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Pulmonary cavernous hemangioma: a case report by Wei Li, Xingxing Zheng, Hongzhe Tian, Yu Xi, Yuhao Liu

“…Abstract Background Cavernous hemangiomas can occur in various internal organs like the liver, kidney, bladder, and skin, or even in subcutaneous tissues. …”
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Examining the relationship between incidence and mortality for commonly diagnosed cancers in the USA: an observational study using population-based SEER database by H Gilbert Welch, Adewole S Adamson, Vishal R Patel

“…The moderate-correlation tercile (r: 0.75 to 0.58) included cancers of the colon, bladder, kidney and uterus. There was little or no relationship between incidence and mortality for cancers in the low-correlation tercile (r: 0.33 to −0.10): melanoma, prostate, breast and thyroid. …”
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Abnormal Migration of Distal End of Ventriculoperitoneal Shunt: A Retrospective Case Series at Sohag University by Ahmed Kamal Abdelhameid, Khaled Nasser Fadle, Bahaa Ghareeb Hassanin

“…Results: We included twelve patients with median age 12.5 months and male to female ratio (3:1) manifested by ventriculoperitoneal shunt complication: extrusion through the anus ( 4 cases 33.3%), scrotum (two patients 16.7%) other sites( 6 patients 50%) like: coiling of the distal end around the flusher, migration to the urinary bladder or flanks, myelomeningocele wound, and an exploratory wound. …”
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MOG associated autoimmune encephalomyelitis with active disease dynamic in imaging examinations and minimal clinical manifestation by E. Tilindytė, I. Muliuolis, R. Samaitienė

“…Progressive encephalopathy and multiple focal neurological symptoms are characteristic to this disease: irritability, disturbed consciousness, weakness, sensory disorders, bowel, bladder dysfunction, spasticity, hyperreflexia, positive Babinsky reflex, paresis, cerebral ataxia, cerebral neuropathy, and spinal cord dysfunction (transverse myelitis). …”
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Fatal intoxication after oral ingestion of amphetamine: Two case reports by Evelyn Pawlik, Felix Mayer, Oliver Temme

“…Body fluids (heart blood, femoral vein blood, urine, cerebrospinal fluid, vitreous humour, and stomach content), organ tissues (myocardium, lung, liver, gall bladder, brain and kidney) and skeletal muscle were examined for amphetamine and amphetamine by-products as well as for other substances e.g. alcohol and pharmaceuticals. …”
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A Vaginal Inlay for Reduction of Stress Urinary Incontinence: Outcome of a Randomized Clinical Trial and Four User Acceptance Studies by Aino Fianu Jonasson, Karin Bryder, Elisabeth Sthengel

“…A multicenter, randomized, controlled clinical trial and four postmarket user acceptance investigations were carried out to document the safety, performance, and user acceptance of Efemia Bladder Support, a novel vaginal inlay for the temporary reduction of stress urinary incontinence (SUI). …”
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Alexis Wound Retractor for Radical Cystectomy: A Safe and Effective Method for Retraction by Ajaydeep S. Sidhu, Eric Marten, Nikita Bodoukhin, George Wayne, Elizabeth Nagoda, Akshay Bhandari, Alan M. Nieder

“…After institutional review board approval, we performed a retrospective chart review from February 2010 through August 2017 of patients undergoing open radical cystectomy with urinary diversion for bladder cancer. We then stratified the groups according to whether or not the surgery was performed with the Alexis or standard Bookwalter retractor. …”
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Postoperative Complications Leading to Death after Coagulum Pyelolithotomy in a Tetraplegic Patient: Can We Prevent Prolonged Ileus, Recurrent Intestinal Obstruction due to Adhesio... by Subramanian Vaidyanathan, Bakul Soni, Gurpreet Singh, Peter Hughes

“…Suprapubic cystostomy predisposed to repeated occurrence of stones in urinary bladder and kidneys. Spinal cord physicians should try to establish intermittent catheterisation regime in tetraplegic patients.…”
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Perioperative complications following spinal fusion in idiopathic scoliosis: A review of 825 cases from the German Spine Registry (DWG-register) – Perioperative complications in id... by Juan Manuel Vinas-Rios, Vincent J. Heck, Fatima Azucena Medina-Govea, Mario Alberto Islas-Aguilar, Nikolaus Kernich

“…A 1.3% rate of major complications and 1.6% rate of minor complications were recorded as follows: spinal cord damage n = 2 (8.4%), subfaszial hematoma n = 2 (8.4%), motor dysfunction n = 1 (4.2%), cerebrospinal fluid (CSF)-leakage n = 7 (29.2%), sensory dysfunction n = 6 (25%), bowel/bladder dysfunction n = 1 (4.2%), superficial site infection n = 2 (8.4%), and pulmonary lung atelectasis n = 3 (12.5%). …”
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Peculiarities of identification of persons who died during martial law (literature review) by A.M. Biliakov, N.M. Erhard

“…The features of identification of putrefied persons are characterized, which consist in the possibility of DNA extraction from smears from the wall of the aorta, the wall of the urinary bladder, brain tissue and intact teeth. It is proven that the identification of dead persons during the martial law is complicated by the influence of the thermal factor, as well as pronounced putrefactive changes. …”
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Sulfatase modifying factor 2 as a predictive biomarker for urothelial carcinoma by Wei-Ting Kuo, Yi-Chen Lee, Jia-Bin Liao, Ching-Jiunn Tseng, Yi-Fang Yang

“…High SUMF2 mRNA levels were associated with poor overall survival (OS) and disease-free survival (DFS) in bladder UC (BLCA) from The Cancer Genome Atlas (TCGA) dataset. …”
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Combined drug delivery and treatment monitoring using a single high frequency ultrasound system by Yesna O. Yildiz, Jia-Ling Ruan, Michael D. Gray, Luca Bau, Richard J. Browning, Christophoros Mannaris, Anne E. Kiltie, Borivoj Vojnovic, Eleanor Stride

“…Additionally, extravasation patterns were influenced by peak negative pressure (PNP) and duty cycle, with the narrower beam width at 5 MHz offering potential advantages for targeted drug delivery. in vivo experiments in a murine bladder cancer model confirmed the efficacy of the STS for real-time imaging and drug delivery, with cavitation dose correlating with drug deposition. …”
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Umbilical Cord Mesenchymal Stem Cells Overexpressing Heme Oxygenase-1 Promotes Symptoms Recovery in Cystitis Rats by Alleviating Neuroinflammation by Qiongqiong Gao, Zhentao Gao, Minzhi Su, Yong Huang, Chi Zhang, Cuiping Li, Hailun Zhan, Bolong Liu, Xiangfu Zhou

“…Interstitial cystitis/bladder pain syndrome (IC/BPS) seriously reduces the patient’s quality of life, yet current therapies only provide partial relief. …”
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Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation by Shoukai Yu, Lingmei Qian, Liling Xu, Jun Ma

“…Significant downregulation of SOX2 expression was observed in colorectal adenocarcinoma, esophageal carcinoma, rectum adenocarcinoma, stomach adenocarcinoma, and testicular germ cell tumors, whereas its expression was upregulated in cervical squamous cell carcinoma, glioblastoma multiforme, lower grade glioma, lung adenocarcinoma, and lung squamous cell carcinoma.Survival analysis showed that low SOX2 expression correlated with better prognosis in bladder cancer, liver hepatocellular carcinoma, kidney renal clear cell carcinoma, and sarcoma, whereas high SOX2 expression was associated with poor prognosis in lung adenocarcinoma, and lung squamous cell carcinoma, glioblastoma multiforme, lower grade glioma. …”
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Strengthening the success rate of suprapubic aspiration in infants by integrating point-of-care ultrasonography guidance: A parallel-randomized clinical trial. by Sadroddin Mahdipour, Seyedeh Nastaran Seyed Saadat, Hamidreza Badeli, Afagh Hassanzadeh Rad

“…A sterile collection of urine samples using suprapubic aspiration (SPA) and bladder catheterization (BC) is helpful for rapid and accurate diagnosis of UTI in infants. …”
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Diagnosis of Distal Cholangiocarcinoma after the Removal of Choledocholithiasis by Yasuhiro Ito, Takeshi Kenmochi, Tomohisa Egawa, Shinobu Hayashi, Atsushi Nagashima, Yuko Kitagawa

“…All patients in Group A had gall bladder stones, compared with 7 patients (19%) in Group B (P<0.01). …”
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