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Acid-Unlocked Two-Layer Ca-Loaded Nanoplatform to Interfere With Mitochondria for Synergistic Tumor Therapy
Published 2025-02-01“…Yilu Zheng,1 Gareth R Williams,2 Ran Hu,1 Sen Tong,3 Jianxiang Xu,1 Tong Wang,1 Yanyan Zhang,1 Junzi Wu,3 Fan Li,4 Yingyu Cai,4 Li-Min Zhu1 1College of Biological Science and Medical Engineering, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, Donghua University, Shanghai, 201620, People’s Republic of China; 2UCL School of Pharmacy, University College London, London, WC1N 1AX, UK; 3The Key Laboratory of Microcosmic Syndrome Differentiation, Education Department of Yunnan, Yunnan University of Chinese Medicine, Kunming, 650500, People’s Republic of China; 4Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, People’s Republic of ChinaCorrespondence: Yingyu Cai, Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, People’s Republic of China, Email yingyu.cai@shgh.cn Li-Min Zhu, College of Biological Science and Medical Engineering, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, Donghua University, Shanghai, 201620, People’s Republic of China, Email lzhu@dhu.edu.cnBackground: The development of selective formulations able to target and kill tumor cells without the application of external energy has shown great promise for anti-tumor therapy.Methods: Here, we report a “nanobomb” that explosively increases Ca content within cells. …”
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Mechanical Properties of Surface-Charged Poly(Methyl Methacrylate) as Denture Resins
Published 2009-01-01Get full text
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Identification of Proteins with Potential Osteogenic Activity Present in the Water-Soluble Matrix Proteins from Crassostrea gigas Nacre Using a Proteomic Approach
Published 2012-01-01“…These results represent a contribution to the study of shell biomineralization process and opens new perspectives for the development of new nacre biomaterials for orthopedic applications.…”
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The Influence of the Chemical Structures of Chitosan and Acid Dye on the Adsorption Process
Published 2012-01-01“…The positive values of the enthalpy changes indicated endothermic attachment of dyes to the biomaterials. CP/AR183 system corresponds to the most energetically favorable phenomenon. …”
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Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair
Published 2025-12-01“…Through transplantation of autologous nerve grafts or other emerging biomaterials functional recovery after facial nerve injury is not ideal in clinical scenarios. …”
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Adsorption of Textile Dyes Using (L.) Fibres: Equilibrium and Kinetics Modelling
Published 2007-06-01“…To compare our results with studies on other biomaterials, the adsorption isotherms and kinetic data were analysed employing the usual models (Freundlich, Langmuir and Temkin isotherms and first- and second-order kinetics). …”
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Hijacking the Cellular Mail: Exosome Mediated Differentiation of Mesenchymal Stem Cells
Published 2016-01-01“…Additionally, exosomes can also bind to matrix proteins such as type I collagen and fibronectin enabling them to be tethered to biomaterials. Overall, the results from this study show the potential of cell derived exosomes in bone regenerative medicine and opens up new avenues for future research.…”
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Calcium/Cobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering
Published 2016-01-01“…The field of tissue engineering currently offers some of the most promising strategies for cartilage restoration, in which assorted biomaterials and cell-based therapies are combined to develop new therapeutic regimens for tissue replacement. …”
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Comparative Studies of Combined Influence of Variables on the Esterification Degree of Pectin Extracted by Sulfuric Acid and Citric Acid
Published 2019-01-01“…The influence of extraction variables on degree of esterification (DE) of pectin was studied due to the significant effects of DE on the properties of the pectin-based functional biomaterials. The extracting agents (sulfuric acid and citric acid), pH value of extraction solution, extraction time, and temperature were selected to study the hydrolysis reaction of carboxylic acid ester by response surface methodology (RSM). …”
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Fibrin Gel as an Injectable Biodegradable Scaffold and Cell Carrier for Tissue Engineering
Published 2015-01-01“…Here, we review the recent advancement in developing fibrin-based biomaterials for the development of injectable tissue engineering scaffold and cell carriers.…”
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Electrochemical Tests to Evaluate the Stability of the Anodic Films on Dental Implants
Published 2011-01-01“…At more positive potentials, localized corrosion starts to occur possibly due to the alloy elements (Ti6Al4V-V and Al) and variable levels of interstitials (Ti-grade 2: C, N, and Fe, mainly). When the biomaterials were submitted to open-circuit conditions, in artificial saliva, the worst corrosion resistance was observed in dental implant (Ti-grade 2), according to the open-circuit potential values and reconstruction rate analysis of these oxide films. …”
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An Updated Review on Properties and Indications of Calcium Silicate-Based Cements in Endodontic Therapy
Published 2022-01-01Get full text
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