The Impact of Oxford Nanopore Technologies Based Methodologies on the Genome Sequencing and Assembly of Romanian Strains of <i>Drosophila suzukii</i> by Attila Cristian Ratiu, Adrian Ionascu, Nicoleta Denisa Constantin

“…The novel dScaff bioinformatics prototype tool allowed us to perform sequence-level quality tests, as well as to represent assembly selections and display both the contig redundancy and the repeats-enriched genomic sub-sequences. …”
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B-CD8+ T Cell Interactions in the Anti-Idiotypic Response against a Self-Antibody by Darel Martínez, Amaury Pupo, Lianet Cabrera, Judith Raymond, Nichol E. Holodick, Ana María Hernández

“…In contrast, B-2 cells were able to stimulate CD8+ T cells only if P3 was added in vitro. Using bioinformatics, a MHC class I-binding peptide from P3 VH region was identified. …”
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QTFN: A General End-to-End Time-Frequency Network to Reveal the Time-Varying Signatures of the Time Series by Tao Chen, Yang Jiao, Lei Xie, Hongye Su

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Passive Monitoring of Parkinson Tremor in Daily Life: A Prototypical Network Approach by Luc J. W. Evers, Yordan P. Raykov, Tom M. Heskes, Jesse H. Krijthe, Bastiaan R. Bloem, Max A. Little

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The Global Assessment of Oilseed Brassica Crop Species Yield, Yield Stability and the Underlying Genetics by Jaco D. Zandberg, Cassandria T. Fernandez, Monica F. Danilevicz, William J. W. Thomas, David Edwards, Jacqueline Batley

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How can mathematics be used to improve burn care? by Ginger Egberts, Fred Vermolen, Qiyao Peng, H.Ibrahim Korkmaz, Paul van Zuijlen

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Screening key genes for intracranial aneurysm rupture using LASSO regression and the SVM-RFE algorithm by Qi Wu, Chunli Yang, Cuilan Huang, Zhiying Lin

“…This study explored the molecular mechanism and potential targets of IA rupture through bioinformatics methods.MethodsThe gene expression matrices of GSE13353, GSE122897, and GSE15629 were downloaded. …”
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Role of CTCF protein in regulating FMR1 locus transcription. by Stella Lanni, Martina Goracci, Loredana Borrelli, Giorgia Mancano, Pietro Chiurazzi, Umberto Moscato, Fabrizio Ferrè, Manuela Helmer-Citterich, Elisabetta Tabolacci, Giovanni Neri

“…We conclude that CTCF has a complex role in regulating FMR1 expression, probably through the organization of chromatin loops between sense/antisense transcriptional regulatory regions, as suggested by bioinformatics analysis.…”
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Best practices for the experimental design of one health studies on companion animal and owner microbiomes – From data collection to analysis by Suzanne B. Clougher, Dagmara Niedziela, Piera Versura, Grace Mulcahy

“…We present the main bioinformatics pipelines in sequencing-data microbiome analysis, as well as data analysis specific to pet-owner microbiome comparison. …”
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An insight into the genome-wide analysis of bacterial defense mechanisms in a uropathogenic Morganella morganii isolate from Bangladesh. by Syed Muktadir Al Sium, Barna Goswami, Sanjana Fatema Chowdhury, Showti Raheel Naser, Mihir Kanti Sarkar, Md Jobaid Faruq, Md Ahashan Habib, Shahina Akter, Tanjina Akhtar Banu, Md Murshed Hasan Sarkar, Md Salim Khan

“…A clinical isolate from a UTI patient in Bangladesh was subjected to high-throughput whole genome sequencing and extensive bioinformatics analysis in order to gather knowledge about the genomic basis of bacterial defenses and pathogenicity in M. morganii. …”
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Key Intelligent Pesticide Prescription Spraying Technologies for the Control of Pests, Diseases, and Weeds: A Review by Kaiqiang Ye, Gang Hu, Zijie Tong, Youlin Xu, Jiaqiang Zheng

“…In the information processing section, information processing methods such as information pre-processing, feature extraction, pest and disease identification, bioinformatics analysis, and time series data are addressed. …”
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A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic Targets by Xinghao Fu, Feihong Ji, Qi He, Xinguang Qiu

“…Then, we contained a variety of elements, for instance, gene expression, the state of survival, gene alterations, protein phosphorylation, immune infiltration, and related cellular pathways, and used a series of bioinformatics methods to investigate the underlying molecular mechanism of YY1 in the etiology or clinical prognosis of various malignancies. …”
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PaleoProPhyler: a reproducible pipeline for phylogenetic inference using ancient proteins by Patramanis, Ioannis, Ramos-Madrigal, Jazmín, Cappellini, Enrico, Racimo, Fernando

“…PaleoProPhyler allows researchers with little bioinformatics experience to efficiently analyze palaeoproteomic sequences, so as to derive insights from this valuable source of evolutionary data. …”
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Lipoprotein Signal Peptide as Adjuvants: Leveraging Lipobox-Driven TLR2 Activation in Modern Vaccine Design by Muhammad Umar, Haroon Afzal, Asad Murtaza, Li-Ting Cheng

“…Recent advances in bioinformatics have significantly improved the prediction of SP structures and cleavage sites, facilitating the rational design of recombinant lipoproteins optimized for immune activation. …”
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Exploration of the metabolomic mechanisms of postmenopausal hypertension induced by low estrogen state by Yao Li, Hui Xin, Zhexun Lian, Wei Zhang

“…Serum estrogen levels, blood pressure measurements, and aortic tissue metabolomics analyses were performed using radioimmunoassay, UHPLC-Q-TOF, and bioinformatics techniques. Based on the above research content, we successfully established a correlation between low estrogen levels and postmenopausal hypertension in rats. …”
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Diversity and composition changes of intestinal fungi in patients with chronic kidney disease by XIE Huichao, XIAO Weidong, HAN Ben

“…ITS DNA sequencing was employed to determine the composition of intestinal fungi， and then bioinformatics analysis was applied to compare the differences in fungal community diversity， structure， and function between the 2 groups. …”
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Landscape of Alternative Splicing Events Related to Prognosis and Immune Infiltration in Glioma: A Data Analysis and Basic Verification by Hong-xin Su, Gang Yang, Fei Su, Chen-xiao Hu, Tao Zhang, Jun-tao Ran, Quan-lin Guan

“…The AS events in glioma were further analyzed, and glioma prognosis-related splicing factors were identified with the use of bioinformatics analysis and laboratory techniques. Further immune infiltration analysis was performed. …”
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Comparison of Proangiogenic Effects of Adipose-Derived Stem Cells and Foreskin Fibroblast Exosomes on Artificial Dermis Prefabricated Flaps by Jiachao Xiong, Zhixiao Liu, Minliang Wu, Mengyan Sun, Yu Xia, Yuchong Wang

“…NGS indicated that there were some differentially expressed miRNAs in both exosomes. Bioinformatics analysis suggested that significantly upregulated hsa-miR-760 and significantly downregulated hsa-miR-423-3p in ADSC-Exo could regulate the expression of the ITGA5 and HDAC5 genes, respectively, to promote the vascularization of skin flaps. …”
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Nonylphenol promotes epithelial-mesenchymal transition in colorectal cancer cells by upregulating miR-151a-3p by Biao Wang, Nianjie Zhang, Lin Dai, Yuanwei Zhang, Shuo Yin, Xuefeng Yang

“…The present experiments showed that NP could activate the WNT/β-catenin signaling pathway, and promoted the migration and invasion of CRC cells by increasing the expression levels of miR-151a-3p. Through bioinformatics analysis and dual-luciferase reporter assays, Fyn-related kinase (FRK) was identified as a target gene of miR-151a-3p. …”
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VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis by Genxiang Rong, Zhenyu Zhang, Wenjing Zhan, Minnan Chen, Jingjing Ruan, Cailiang Shen

“…To address the lack of studies focused on synovial cells in OA, we evaluated the expression patterns and roles of the MAPK signaling pathway components in OA synovial tissues using bioinformatics. The JUN, MYC, and VEGFA expression levels were significantly higher in the synovial tissues of patients with OA than in control tissues. …”
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