Circular RNAs in cancer: roles, mechanisms, and therapeutic potential across colorectal, gastric, liver, and lung carcinomas by Ayushi Malviya, Rajabrata Bhuyan

“…The approach involved assessing full-text reports on PMC, utilizing keywords such as “CircRNA” and “Cancer types,” coupled with bioinformatics, experimental assays, or clinical investigations. …”
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Convergent evolution of oxidized sugar metabolism in commensal and pathogenic microbes in the inflamed gut by Sophia Levy, Angela K. Jiang, Maggie R. Grant, Gabriela Arp, Glory Minabou Ndjite, Xiaofang Jiang, Brantley Hall

“…The divergent pathway in commensals includes a putative 5-KDG aldolase (GudL) and an uncharacterized ABC transporter (GarABC) that recapitulate the function of their non-homologous counterparts in pathogens. A systematic bioinformatic search for the gud/gar pathway in gut microbes identified 887 species putatively capable of metabolizing oxidized sugars. …”
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Agreement of Immunoassay and Tandem Mass Spectrometry in the Analysis of Cortisol and Free T4: Interpretation and Implications for Clinicians by Rochelle E. Tractenberg, Jacqueline Jonklaas, Steven J. Soldin

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Systematic Review into Diagnostics for Post-Kala-Azar Dermal Leishmaniasis (PKDL) by Emily R. Adams, Inge Versteeg, Mariska M. G. Leeflang

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Elderly Patients with Mild Cognitive Impairment Exhibit Altered Gut Microbiota Profiles by Qiong Pan, Ya-Qian Li, Ke Guo, Min Xue, Yu Gan, Kejian Wang, Da-Bao Xu, Qiu-Yun Tu

“…Fecal samples were collected for 16S ribosomal RNA (rRNA) quantitative arrays and bioinformatics analysis. Results. A principal coordinates analysis (PCoA) and nonmetric multidimensional scaling (NMDS) both demonstrated that the microbial composition of participants with MCI deviated from that of healthy control participants. …”
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Serum Extracellular Vesicle-derived microRNA Profiles in Patients with ST-segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention by Weikun Chen, Yeshen Zhang, Yining Dai, Siyu Kong, Haobin Liu, Yu He, Ning Tan, Yuanhui Liu

“…The miRNA differential expression profiles of serum EVs were obtained through next-generation sequencing combined with bioinformatics analysis. Results: In patients with AMI, compared with controls without AMI, 15 differentially expressed miRNAs (11 upregulated and 4 downregulated) were identified. …”
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CEACAM5 exacerbates asthma by inducing ferroptosis and autophagy in airway epithelial cells through the JAK/STAT6-dependent pathway by Si Liu, Li Chen, Yunxiao Shang

“…This study focused on the role of bronchial epithelial cells in asthma pathophysiology.Methods Bioinformatics was used to identify key asthmarelated genes. …”
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DNA promoter task-oriented dictionary mining and prediction model based on natural language technology by Ruolei Zeng, Zihan Li, Jialu Li, Qingchuan Zhang

“…Recent advancements in bioinformatics have leveraged deep learning and natural language processing (NLP) to enhance promoter prediction accuracy. …”
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Online COVID-19 Infection Diagnoses via Chest X-Ray Images using Alexnet Deep Learning Model by Ali Heidari, Hamidreza Erfanian

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First report of the chloroplast and mitochondrial genomes of the Indian pitcher plant, Nepenthes khasiana Hook.f. by Ruchishree Konhar, Debasis Dash, Devendra Kumar Biswal

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ZNF652-Induced circRHOT1 Promotes SMAD5 Expression to Modulate Tumorigenic Properties and Nature Killer Cell-Mediated Toxicity in Bladder Cancer via Targeting miR-3666 by Hu Ke, Jiabin Zhang, Fei Wang, Yunhe Xiong

“…Subsequently, we conducted bioinformatics analysis followed by RNA pull-down, ChIP, and luciferase reporter assays, from which we found that circRHOT1 expression in BC cells could be regulated by ZNF652, and circRHOT1 could promote SMAD5 expression to regulate BC cell cellular progression by sponging miR-3666. …”
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Age-Related Modifications in Circulating IL-15 Levels in Humans by Sebastiano Gangemi, Giorgio Basile, Daniela Monti, Rosaria Alba Merendino, Giuseppe Di Pasquale, Ursula Bisignano, Vittorio Nicita-Mauro, Claudio Franceschi

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Comparative Study of Modified Quantitative Buffy Coat and Two Rapid Tests in Comparison with Peripheral Blood Smear in Malaria Diagnosis in Mumbai, India by Manali M. Kocharekar, Sougat S. Sarkar, Debjani Dasgupta

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Molecular Modeling and Simulation Analysis of Antimicrobial Photodynamic Therapy Potential for Control of COVID-19 by Maryam Pourhajibagher

“…In this in silico study, SARS-CoV-2-SG was selected as a novel target for curcumin as a photosensitizer during aPDT to exploit its physicochemical properties, molecular modeling, hierarchical nature of protein structure, and functional analysis using several bioinformatics tools and biological databases. The results of a detailed computational investigation revealed that SARS-CoV-2-SG is most similar to 6VXX_A, with 100% query cover and identity. …”
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Comparison of Two Meta-Analysis Methods: Inverse-Variance-Weighted Average and Weighted Sum of Z-Scores by Cue Hyunkyu Lee, Seungho Cook, Ji Sung Lee, Buhm Han

“…The meta-analysis has become a widely used tool for many applications in bioinformatics, including genome-wide association studies. …”
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Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification by Louna Fruchard, Anamaria Babosan, Andre Carvalho, Manon Lang, Blaise Li, Magalie Duchateau, Quentin Giai Gianetto, Mariette Matondo, Frederic Bonhomme, Isabelle Hatin, Hugo Arbes, Céline Fabret, Enora Corler, Guillaume Sanchez, Virginie Marchand, Yuri Motorin, Olivier Namy, Valérie de Crécy-Lagard, Didier Mazel, Zeynep Baharoglu

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Identification and characterization of interacting proteins of transcription factor DpWRI1-like related to lipid biosynthesis from microalga Dunaliella parva by Lingru Ruan, Limei Huang, Lina Wu, Jinghui Gu, Yanyan Liang, Xiuli Liang, Changhua Shang

“…Bimolecular fluorescence complementation assay further validated the interaction between DpWRI1-like and interacting proteins ACBD6 and DCA. The further bioinformatics analyses of interacting proteins were conducted. …”
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Identification of PET/CT radiomic signature for classification of locally recurrent rectal cancer: A network-based feature selection approach by Sara Dalmonte, Maria Adriana Cocozza, Dajana Cuicchi, Daniel Remondini, Lorenzo Faggioni, Paolo Castellucci, Andrea Farolfi, Emilia Fortunati, Alberta Cappelli, Riccardo Biondi, Arrigo Cattabriga, Gilberto Poggioli, Stefano Fanti, Gastone Castellani, Francesca Coppola, Nico Curti

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Annexin A8 deficiency delays atherosclerosis progression by Carmen Gutiérrez‐Muñoz, Rafael Blázquez‐Serra, Irene San Sebastian‐Jaraba, Sandra Sanz‐Andrea, Maria J. Fernández‐Gómez, Gonzalo Nuñez‐Moreno, Pablo Mínguez, Joan Carles Escolá‐Gil, Paula Nogales, Veronique Ollivier, Jose L. Martín‐Ventura, Benoit Ho‐Tin Noe, Ursula Rescher, Nerea Méndez‐Barbero, Luis M. Blanco‐Colio

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Metabolomic and lipidomic pathways in aneurysmal subarachnoid hemorrhage by Bosco Seong Kyu Yang, Spiros L. Blackburn, Philip L. Lorenzi, Huimahn A. Choi, Aaron M. Gusdon

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