Showing 1,001 - 1,020 results of 2,004 for search '"bioinformatics"', query time: 0.05s Refine Results
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    What are biopharmaceuticals? by Abhay H. Pande, Yenisetti Rajendra Prasad, J. Anakha

    Published 2025-01-01
    “…With advancements in genetic engineering, biotechnology, and bioinformatics, the development and approval rates of new biopharmaceuticals have surged, placing them at the forefront of the pharmaceutical field. …”
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    Complete Whole-Genome Sequence of Streptomyces sp. MUM 178J, a Potential Anti-Vibrio Agent by Ke-Yan Loo, Loh Teng-Hern Tan, Kah-Ooi Chua, Priyia Pusparajah, Kok-Gan Chan, Learn-Han Lee, Jodi Woan-Fei Law, Vengadesh Letchumanan

    Published 2024-02-01
    “…Further analysis with the bioinformatics tool, antiSMASH (antibiotics & Secondary Metabolite Analysis Shell), detected nine biosynthetic gene clusters displaying more than 70% similarity to known gene clusters, including one associated with melanin production. …”
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    Article
  10. 1010

    17β-estradiol promotes osteogenic differentiation of BMSCs by regulating mitophagy through ARC by Jingcun Shi, Jin Wen, Longwei Hu

    Published 2025-01-01
    “…RNA sequencing and bioinformatics analyses were conducted to explore potential mechanisms of ARC regulation in BMSCs osteogenic differentiation. …”
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  11. 1011

    Interferon signaling and ferroptosis in tumor immunology and therapy by Wei Hu, Ziqian Zhao, Jianxin Du, Jie Jiang, Minghao Yang, Maojin Tian, Peiqing Zhao

    Published 2024-08-01
    “…Differential gene analysis revealed key genes involved in CD8 + T cell exhaustion, and their downstream factors were explored using bioinformatics tools. The expression levels of interferon-related genes associated with Ferroptosis were analyzed using data from the TCGA database, and their relevance to tumor tissue Ferroptosis and patients’ prognosis was determined. …”
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    Naringenin induces ferroptosis in osteosarcoma cells through the STAT3-MGST2 signaling pathway by Yingang Li, Xizhuang Bai

    Published 2025-02-01
    “…In this study, we found that naringenin significantly reduced the viability of osteosarcoma cells while increasing the accumulation of reactive oxygen species (ROS), iron overload, and the excessive expression of malondialdehyde (MDA). Bioinformatics analysis revealed that microsomal glutathione S-transferase 2 (MGST2) is highly expressed in osteosarcoma cells. …”
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  14. 1014

    Whole genome sequence of Streptomyces colonosanans strain MUSC 93JT isolated from mangrove forest in Malaysia by Hooi-Leng Ser, Jodi Woan-Fei Law, Wen-Si Tan, Wai-Fong Yin, Kok-Gan Chan

    Published 2020-03-01
    “…Analysis using a bioinformatics tool, antiSMASH predicted a total of four biosynthetic gene clusters which displayed similarity of more than 70% to known gene clusters and one of which was associated with the production of a natural protectant, ectoine. …”
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    Schistosoma Tegument Proteins in Vaccine and Diagnosis Development: An Update by Cristina Toscano Fonseca, Gardênia Braz Figueiredo Carvalho, Clarice Carvalho Alves, Tatiane Teixeira de Melo

    Published 2012-01-01
    “…The development of a vaccine against schistosomiasis and also the availability of a more sensitive diagnosis test are important tools to help chemotherapy in controlling disease transmission. Bioinformatics tools, together with the access to parasite genome, published recently, should help generate new knowledge on parasite biology and search for new vaccines or therapeutic targets and antigens to be used in the disease diagnosis. …”
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    The dysregulation of PARP9 expression is linked to apoptosis and DNA damage in gastric cancer cells. by Yating Li, Xing Wang, Xiaolong Liu, Xiangjie Li, Jianling Zhang, Yulan Li

    Published 2024-01-01
    “…<h4>Methods</h4>The expression and prognostic significance of PARP9 in gastric cancer (GC) were examined using bioinformatics approaches. Cell lines with either knockdown or overexpression of PARP9 were established through lentiviral transduction, and the role of PARP9 in the malignant phenotypes of GC cells was validated via CCK8 assays, wound healing assays, clonogenic assays, and Transwell migration experiments. …”
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    Rapid Identification of Drug-Resistant Tuberculosis Genes Using Direct PCR Amplification and Oxford Nanopore Technology Sequencing by Kaishun Zhao, Chunlin Tu, Wei Chen, Haiying Liang, Wenjing Zhang, Yilei Wang, Ye Jin, Jianrong Hu, Yameng Sun, Jun Xu, Yanfang Yu

    Published 2022-01-01
    “…This study established a sequencing method and bioinformatics pipeline for resistance gene analysis using an Oxford Nanopore Technologies sequencer. …”
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    Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/β-Catenin Pathway by Kexin Chen, Jiachao Xiong, Sha Xu, Minliang Wu, Chunyu Xue, Minjuan Wu, Chuan Lv, Yuchong Wang

    Published 2022-01-01
    “…In this study, we applied hADSC-Exo and HFF-Exo to adipose grafts and explored the potential regeneration mechanism through various means such as bioinformatics, immunofluorescence, immunohistochemistry, and adipogenic differentiation. …”
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