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  1. 861

    The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs) by Camila Sabatini, Huey-Jiun Lin, Galib Ovik, Richard Hall, Techung Lee

    Published 2025-01-01
    “…Abstract Background Bioengineering of human teeth for replacement is an appealing regenerative approach in the era of gene therapy. …”
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  2. 862

    Using a Two-Steps Clustering and PCA Analysis for Stratified Chronic Non-Cancer Pain Care: A Retrospective Cross-Sectional Study by Peiró AM, Barrachina J, Escorial M, Aguado I, Margarit C, Grimby-Ekman A

    Published 2025-02-01
    “…Ana M Peiró,1,2 Jordi Barrachina,1 Mónica Escorial,1 Isidro Aguado,1 César Margarit,1,3 Anna Grimby-Ekman4 1Neuropharmacology Applied to Pain (NED), Clinical Pharmacology Unit, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, 03010, Spain; 2Institute of Bioengineering, University Miguel Hernández, Elche, 03202, Spain; 3Pain Unit, Alicante Department of Health -General Hospital, Alicante, 03010, Spain; 4School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenCorrespondence: Ana M Peiró, Alicante Institute for Health and Biomedical Research (ISABIAL), Hospital General Universitario Doctor Balmis, c/Pintor Baeza, 12, Alicante, 03010, Spain, Email apeiro@umh.esPurpose: Given the number of people who suffer from chronic pain and the impact on healthcare resources, it is imperative that the people with pain receive an appropriate matched treatment due and stratified care. …”
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  3. 863

    In vitro Antibacterial Effect of Reduning Combined with Polymyxin on Carbapenem Resistant Klebsiella pneumoniae by Shangguan ZF, Chen HL, Li YF, Shi N, Mao QF

    Published 2025-01-01
    “…Zui-Fei Shangguan,1 Hong-Lei Chen,2 Yi-Fan Li,3 Na Shi,4 Qi-Fen Mao2 1Department of Clinical Laboratory, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310006, People’s Republic of China; 2Department of Clinical Laboratory, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, 310012, People’s Republic of China; 3College of Laboratory Medicine and College of Bioengineering, Hangzhou Medical University, Hangzhou, Zhejiang, 311399, People’s Republic of China; 4Medical Laboratory, Second Sanatorium of Air Force Healthcare Center for Special Services, Hangzhou, Zhejiang, 310007, People’s Republic of ChinaCorrespondence: Qi-Fen Mao, Department of Clinical Laboratory, Tongde Hospital of Zhejiang Province, 234#, Gucui Road, Hangzhou, Zhejiang, 310012, People’s Republic of China, Email maoqifen@alu.zcmu.edu.cnObjective: This study aimed to investigate the status of carbapenem-resistant strains of Klebsiella pneumoniae isolated from the Department of Microbiology, Zhejiang Tongde Hospital between September 2023 and February 2024, and to examine the in vitro antibacterial effect of Reduning combined with polymyxin on carbapenem-resistant Klebsiella pneumoniae (CRKP), which may provide evidence on the application of Reduning in the clinical anti-infective therapy.Methods: A total of 50 different isolates of CRKP were collected, and the minimum inhibitory concentrations (MIC) of polymyxin, Reduning and polymyxin plus Reduning were measured with microbroth dilution method. …”
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