Investigating the Biological Impact of Melatonin on Male Albino Mice: A Comprehensive Characterization by Hanan H. ALQaragholy

“…In comparison to the control therapy, the results showed that the Mel dose of 10 mg/ml had the greatest impact on lowering the levels of thyroid hormones (T3 and T4), lowering the levels of the liver enzymes Alanine transaminase (ALT), Aspartate aminotransferase (AST), and Total serum bilirubin (TSB) and lowering lipid profile (cholesterol (CHO), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), and triglycerides (TG)). …”
Get full text

A Rare Case of Post-Partum Hemorrhage with Refractory Thrombotic Microangiopathy, and Hepatic Infarction: A Diagnostic Dilemma with High Mortality by Naved Yousuf Hasan, Asiah Salem Rugaan, Noha Ahmed Mohamed Ali, Masood Iqbal

“…During her illness, she developed rising liver enzymes and bilirubin, diffuse intravascular coagulation, renal failure, alveolar hemorrhage, and acute fulminant hepatic failure. …”
Get full text

Lipemia Interferences in Biochemical Tests, Investigating the Efficacy of Different Removal Methods in comparison with Ultracentrifugation as the Gold Standard by Neda Soleimani, Sahand Mohammadzadeh, Fateme Asadian

“…According to our study, there were significant differences before and after ultracentrifugation in all lipemic levels and for all parameters except for alanine aminotransferase (ALT), alkaline phosphatase (ALP), bilirubin, and uric acid. Based on allowable inaccuracy for each parameter, calcium, magnesium, phosphorus, total protein, iron, total iron-binding capacity (TIBC), urea, and chloride are being influenced by all lipemic degree and neither serum dilution nor using serum blank is as effective as ultracentrifuge for elimination. …”
Get full text

Tracking of The Most Significant Laboratory Parameters For The Identification of Covid-19: An Overview on The Different Blood Tests by Seenaa Ali

“…Also, laboratory data recorded an elevation in Leukocyte, ESR, PT, D-dimer, PCT, CRP, ALT, AST, Bilirubin, Creatinine, CK, LDH, Ferritin, Troponin, Myoglobin, IL-6, IL10 and TNF. …”
Get full text

Evaluation of Serum Kallistatin Levels in Women with Preeclampsia and its Role in Assessing Preeclampsia Severity by Rangeen Badri Mahdi, Esraa Hameed Al-Maini

“…In PE, age, gestational age, and platelets correlated directly with kallistatin, but systolic and diastolic blood pressure, alanine transaminase, aspartate aminotransferase, and total serum bilirubin correlated inversely. Kallistatin had higher sensitivity than specificity and comparable negative to positive predictive values. …”
Get full text

Biochemical Markers of Bone Turnover in Patients with β-Thalassemia Major: A Single Center Study from Southern Pakistan by Sadia Sultan, Syed Mohammed Irfan, Syed Ijlal Ahmed

“…No correlation was found between indirect bilirubin and skeletal parameters, calcium and parathyroid hormone (P>0.05). …”
Get full text

Influence of Moxifloxacin on Hepatic Redox Status and Plasma Biomarkers of Hepatotoxicity and Nephrotoxicity in Rat by Ayokanmi Ore, Ebenezer Tunde Olayinka

“…After seven days, plasma urea, bilirubin, and creatinine were significantly (P<0.05) elevated in the MXF-treated animals. …”
Get full text

Systemic Lupus Erythematosus with Concurrent Thrombotic Thrombocytopenic Purpura: A Case Report of Diagnostic Challenges and Management Approaches by Sonu Rahul Tej Gaddam, Manideep Katta, Sumana Simarla, Pruthvi Raj Kukunoor, Manichandana Katta

“…Clinical findings, including schistocytes on peripheral smear, elevated lactate dehydrogenase and indirect bilirubin, prompted investigation for ADAMTS13 activity.…”
Get full text

The Correlation between Gut Microbiota and Serum Metabolomic in Elderly Patients with Chronic Heart Failure by Zhenhua Wang, Zhaoling Cai, Markus W. Ferrari, Yilong Liu, Chengyi Li, Tianzhang Zhang, Guorong Lyu

“…Klebsiella was positively correlated with bilirubin and ethylsalicylate. Klebsiella was negatively correlated with citramalate, hexanoylcarnitine, inosine, isovalerylcarnitine, methylmalonate, and riboflavin. …”
Get full text

Long-Term Survival and Risk Factors in Patients with Hepatitis B-Related Hepatocellular Carcinoma: A Real-World Study by Yu Zhu, Ling-Ling Gu, Fa-Biao Zhang, Guo-Qun Zheng, Ting Chen, Wei-Dong Jia

“…Multivariate Cox proportional-hazards regression analysis showed that microvascular invasion (MVI), Edmondson III/IV, BCLC stage B, and total bilirubin (TB) > 20.5 μmol/L were independent risk factors in patients with hepatitis B-related hepatocellular carcinoma after radical hepatectomy.…”
Get full text

Development of a LASSO machine learning algorithm-based model for postoperative delirium prediction in hepatectomy patients by Yu Zhu, Renrui Liang, Ying Wang, Jian-Jun Yang, Ning Zhou, Cheng-Mao Zhou

“…Results The final variables selected by the LASSO method were: Ramelteon, Age, Sex, Alcohol, Viral status, Cardiovascular disease, ASA class, Total bilirubin, Prothrombin time, Laparoscopic approach, and Blood transfusion. …”
Get full text

Therapy with Interleukin-22 Alleviates Hepatic Injury and Hemostasis Dysregulation in Rat Model of Acute Liver Failure by Tariq Helal Ashour

“…The following parameters were investigated: (1) survival rate, (2) serum levels of liver function enzymes (aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP)), total bilirubin (TBILI), and total albumen (ALB), (3) blood clotting tests (prothrombin time (PT), activated partial thromboplastin time (aPTT), and fibrinogen level (FIB)) and white blood cells (WBCs), red blood cells (RBCs), and platelet counts, (4) hepatic levels of tumor necrosis factor-α (TNF-α) and cyclooxygenase-2 (COX-2), and (5) liver histopathology. …”
Get full text

Factors associated with biloma formation in biliary atresia patients after Kasai operation and outcomes of percutaneous transhepatic biliary drainage by Niramol Tantemsapya, Rattakan Jutiyon, Mongkol Laohapensang

“…There was a significant decrease in bilirubin levels (p=0.028) and gamma-glutamyltransferase (GGT) (p=0.021) after biloma treatment. …”
Get full text

Safe and Successful Yttrium-90 Resin Microsphere Radioembolization in a Heavily Pretreated Patient with Chemorefractory Colorectal Liver Metastases after Biliary Stent Placement ab... by Vlasios S. Sotirchos, Elena N. Petre, Karen T. Brown, Lynn A. Brody, Michael I. D’Angelica, Ronald P. DeMatteo, Nancy E. Kemeny, Constantinos T. Sofocleous

“…One month prior to radioembolization, a biliary stent was placed above the level of the ampulla to relieve tumor-related biliary obstruction and normalize bilirubin levels.…”
Get full text

Frequency Of Prolonged Qtc in Patients With Decompensated Chronic Liver Disease In A Rural Cohort Of Sindh by Adeel Ahmed, Bushra Rabbani, Muhammad Kamran, Ammarah Saeed, Jameel Ahmed

“…Age, Child–Turcotte–Pugh (CTP)  class and Bilirubin of the patients were significantly associated with QTc prolongation. …”
Get full text

Transjugular Retrograde Obliteration prior to Liver Resection for Hepatocellular Carcinoma Associated with Hyperammonemia due to Spontaneous Portosystemic Shunt by Fumio Chikamori, Nobutoshi Kuniyoshi

“…Admission laboratory data revealed albumin, 2.9 g/dL; total bilirubin, 1.3 mg/dL; plasma ammonia level (NH3), 152 g/dL; total bile acid (TBA) 108.5 μmoL/L; indocyanine green retention rate at 15 min (ICG15), 63%. …”
Get full text

Acquired Elliptocytosis as a Manifestation of Myelodysplastic Syndrome Associated with Deletion of Chromosome 20q by Sukesh Manthri, Naresh K. Vasireddy, Sindhura Bandaru, Swati Pathak

“…A slightly elevated bilirubin of 1.2 mg/dl spurred a hemolytic workup. …”
Get full text

Tuberculous cardiac tamponade presenting as severe hypoxic hepatitis by Valdes Roberto Bollela, Fernanda Guioti Puga, Rodrigo Carvalho Santana

“…Laboratory tests revealed alanine aminotransferase 14,620 IU/L, bilirubin 10.8 mg/dL and serum lactate 13.9 mmol/L. …”
Get full text

Evaluation of Adrenal Function in Nonhospitalized Patients with Cirrhosis by Maryam Moini, Mitra Yazdani Sarvestani, Mesbah Shams, Masood Nomovi

“…These patients were not statistically different from those with normal adrenal function in levels of serum creatinine or bilirubin, MELD score, or presence of cirrhosis related complications. …”
Get full text

Serum IgG level in autoimmune liver diseases and its significance: Is there a need to revisit existing criteria? Experience from a tertiary care center by Annapoorani Varadarajan, Archana Rastogi, Rakhi Maiwall, Chaggan Bihari, Sherin Thomas, Saggere Muralikrishna Shasthry

“…Results: Among AIH patients, IgG values of >2 times the upper limit of normal (ULN) were associated with significant elevation of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), bilirubin, and necroinflammatory activity. IgG level of >1.1 times ULN lacks specificity in differentiating AIH from the control group. …”
Get full text