Antimicrobial Stewardship in Daily Practice: Managing an Important Resource by Nicole Le Saux, Canadian Paediatric Society, Infectious Diseases and Immunization Committee

“…Antimicrobial stewardship is a recent concept that embodies the practical, judicious use of antimicrobials to decrease adverse outcomes from antimicrobials while optimizing the treatment of bacterial infections to reduce the emergence of resistant pathogens. …”
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Composition and liquid-to-solid maturation of protein aggregates contribute to bacterial dormancy development and recovery by Celien Bollen, Sofie Louwagie, Femke Deroover, Wouter Duverger, Ladan Khodaparast, Laleh Khodaparast, Dieter Hofkens, Joost Schymkowitz, Frederic Rousseau, Liselot Dewachter, Jan Michiels

“…Abstract Recalcitrant bacterial infections can be caused by various types of dormant bacteria, including persisters and viable but nonculturable (VBNC) cells. …”
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Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy by Mahmood Almosuli, Anna Kirtava, Archil Chkhotua, Lia Tsveniashvili, Nina Chanishvili, Sumaiya Safia Irfan, Emily Ng, Hope McIntyre, Adam J. Hockenberry, Robyn P. Araujo, Weidong Zhou, Ngoc Vuong, Barbara Birkaya, Lance Liotta, Alessandra Luchini

“…From a human health perspective, these data suggest that temperate phages may facilitate bacterial infections rather than function as protective agents. …”
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Identification of pathogenic bacteria by biosensors in water and wastewater by Sakineh Hargolzadeh, Soheila Kashanian, Maryam Nazari

“…On the other hand, due to the ability of antibiotics to prevent or treat bacterial infections, they have been used as the main method of infection treatment in humans and animals for the past two decades. …”
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Composite Hydrogel of Poly(acrylamide) and Starch as Potential System for Controlled Release of Amoxicillin and Inhibition of Bacterial Growth by Ana V. Torres-Figueroa, Cinthia J. Pérez-Martínez, Teresa del Castillo-Castro, Enrique Bolado-Martínez, María A. G. Corella-Madueño, Alejandro M. García-Alegría, Tania E. Lara-Ceniceros, Lorena Armenta-Villegas

“…The optimal release profile at physiological conditions and the powerful bacteria growth inhibition effects of amoxicillin-loaded hydrogels evidenced its potential for biomedical applications, particularly in oral administration and the local treatment of bacterial infections.…”
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Analysis of Three Penicillin Antibiotics (Ampicillin, Amoxicillin and Cloxacillin) of Several Iranian Pharmaceutical Companies by HPLC by A. Ashnagar, N. Gharib Naseri

“…Penicillin has been the most widely used antibiotic for many gram-positive bacterial infections. In this research the purity of the standard active ingredients of the various dosage forms of three penicillins (Amoxicillin, Cloxacillin and Ampicillin) imported and the purity percentage of the active ingredients in each of the various dosage forms of these drugs manufactured by several pharmaceutical companies of Iran (Kosar, Farabi and Jaber Ibn Hayan) were investigated and determined by HPLC technique. …”
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IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection. by Jan-Eric Turner, Brigitta Stockinger, Helena Helmby

“…In this study we show that IL-22, a cytokine important in defence against bacterial infections in the intestinal tract, is also a critical mediator of anti-helminth immunity. …”
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Role of plasmids in antibiotic resistance in clinical infections and implications for epidemiological surveillance: a review by Ayodele Oluwaseun Ajayi, Olajide Joseph Akinjogunla, Adebowale Toba Odeyemi, Akinyomade Oladipo Owolabi

“…Healthcare in LMICs should be supported to build capacity in WGS and molecular surveillance to effectively prevent and control AR bacterial infections.…”
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Inflammation and Immune Response in COPD: Where Do We Stand? by Nikoletta Rovina, Antonia Koutsoukou, Nikolaos G. Koulouris

“…Furthermore, viral and bacterial infections interfere with the chronic inflammation seen in stable COPD and exacerbations via pathogen-associated molecular patterns (PAMPs). …”
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High-Dose Antibiotics in Intensive Care: A Review of Their Role in Combatting and Contributing to Antimicrobial Resistance by Galo G. Farfán-Cano, Carlos R. Cedeño-Cevallos

“…This systematic review analyzed randomized controlled trials (RCTs) published between 2020 and 2024, focusing on high-dose regimens for gram-negative bacterial infections, cellulitis, and ventilated hospital-acquired bacterial pneumonia (vHABP). …”
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Sepsis and Pleural Empyema Caused by Streptococcus pyogenes after Influenza A Virus Infection by Fumihiro Ochi, Hisamichi Tauchi, Toshihiro Jogamoto, Hiromitsu Miura, Tomozo Moritani, Kozo Nagai, Eiichi Ishii

“…These observations suggest that the immunological mechanisms induced by the influenza virus can play an important role in influencing the susceptibility to secondary bacterial infections, such as GAS, in children.…”
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Recent advances in the biosynthesis of polysaccharide-based antimicrobial glycoconjugate vaccines by Yuhui Wang, Yuhui Wang, Yuhui Wang, Yuhui Wang, Haodi Liu, Haodi Liu, Haodi Liu, Haodi Liu, Baoying Wang, Baoying Wang, Baoying Wang, Baoying Wang, Gülzire Gheyret, Jingliang Qin, Hanlin Wang, Hanlin Wang, Hanlin Wang, Hanlin Wang, Yuhan Di, Yuhan Di, Yuhan Di, Yuhan Di, Yanling Wang, Juan Wang, Haining Tan, Haining Tan, Haining Tan, Haining Tan

“…Glycoconjugate vaccines are a vital category of effective and safe commercial vaccines that have significantly reduced the global prevalence of drug-resistant bacterial infections. These vaccines are synthesized by covalently linking bacterial polysaccharide antigens to a carrier protein. …”
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Potential use of peptides mimicking CRAC/CARC domains as antivirulence therapies to inhibit RTX toxins activities by Vanesa Herlax

“…In recent years, research efforts have increased to develop new therapeutics aimed at combating antibiotic-resistant bacterial infections. These efforts focus on inhibiting the virulence factors bacteria secrete to proliferate. …”
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A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment by Sandra Viz-Lasheras, Alberto Gómez-Carballa, Xabier Bello, Irene Rivero-Calle, Ana Isabel Dacosta, Myrsini Kaforou, Dominic Habgood-Coote, Aubrey J. Cunnington, Marieke Emonts, Jethro A. Herberg, Victoria J. Wright, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Daniela S. Kohlfürst, Nina Schweintzger, Michiel Van der Flier, Ronald de Groot, Luregn J. Schlapbach, Philipp Agyeman, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Ulrich Von Both, Marko Pokorn, Dace Zavadska, María Tsolia, Henriëtte A. Moll, Clementien Vermont, Michael Levin, Federico Martinón-Torres, Antonio Salas, On behalf of EUCLIDS, PERFORM, and DIAMONDS consortia

“…Additionally, we demonstrate that existing signatures for broadly distinguishing viral/bacterial infections and viral/bacterial pneumonias are ineffective in distinguishing M. pneumoniae from viral pneumonia. …”
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A Review on Synthesis, Optimization, Mechanism, Characterization, and Antibacterial Application of Silver Nanoparticles Synthesized from Plants by Sunday Adewale Akintelu, Yao Bo, Aderonke Similoluwa Folorunso

“…Furthermore, a thorough discussion on the recent advances in the application of AgNPs synthesized from plant as therapeutic agent against bacterial infections was made.…”
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Application of a Chairside Anaerobic Culture Test for Endodontic Treatment by Masahiro Yoneda, Seidai Kita, Nao Suzuki, Sonia M. Macedo, Kosaku Iha, Takao Hirofuji

“…Periapical lesions are caused by bacterial infections. The fundamental objective of endodontic treatment is to eliminate bacteria present in the root canal system because they play an important role in the development and maintenance of periapical lesions. …”
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Hemophagocytic Lymphohistiocytosis Associated with Respiratory Syncytial Virus Infection in an Immunocompetent Elderly Patient by Ralph Kamel, Rubal Sharma, Divya Asti, Arshpal Gill, Yevgeniy Skaradinskiy

“…The secondary form presents later in life and is associated with several conditions mainly malignancy, autoimmune diseases, viral or bacterial infections, and hematological diseases. We present the case of an 80-year-old female patient who initially presented with an acute viral syndrome secondary to respiratory syncytial virus. …”
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Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis by Elisabetta Volpe, Luca Battistini, Giovanna Borsellino

“…The discovery of the T helper (Th) 17 lineage, involved in the protection against fungal and extracellular bacterial infections, has profoundly revolutionized our current understanding of T cell-mediated responses in autoimmune diseases, including multiple sclerosis (MS). …”
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A study of bacterial community structure of shrimp farms along the Ratnagiri coast, Maharashtra by Bhavesh Choudhary, Anil S. Pawase, Gajanan S. Ghode, Raju M. Tibile, Varsha R. Bhatkar, Divyashree Choudhary, Utkarsh Choudhary

“…However, these farming practices also witness disease outbreaks due to viral and bacterial infections. Among the bacterial infections, Vibrios are the most important bacterial causative agents found in shrimp farms. …”
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Chitosan Superabsorbent Biopolymers in Sanitary and Hygiene Applications by Peenal Arvind Mistry, Meera Nambidas Konar, Srinivasan Latha, Utkarsh Chadha, Preetam Bhardwaj, Tolera Kuma Eticha

“…Several problems are associated with using chemical-based sanitary products, which are difficult to degrade easily and cause nappy rash and bacterial infections in babies. Therefore, there is an increasing shift towards natural-based sanitary products because of their biodegradability, non-toxicity, and biocompatibility. …”
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