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301
Photodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms
Published 2025-01-01“…Abstract The escalating hazards posed by bacterial infections underscore the imperative for pioneering advancements in next-generation antibacterial modalities and treatments. …”
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302
Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma
Published 2017-01-01“…Its acute form is associated with severe bacterial infections and hematological malignancies. It has a fulminant presentation with prolonged bleeding times and diffuse thrombosis. …”
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303
Mpox Virus as a Global Public Health Emergency: A Scoping Review
Published 2025-01-01“…This comprehensive analysis describes the virus epidemiology, pathogenesis, clinical manifestations, complications including secondary bacterial infections, diagnosis, treatment and vaccination. …”
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304
Screening of the Dichloromethane: Methanolic Extract of Centella asiatica for Antibacterial Activities against Salmonella typhi, Escherichia coli, Shigella sonnei, Bacillus subtili...
Published 2020-01-01“…Bacterial infections are responsible for a large number of deaths every year worldwide. …”
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305
Characterization of YdgH: a mediator of beta-lactam susceptibility in Enterobacterales
Published 2025-01-01“…ABSTRACT Beta-lactam antibiotics are often the treatment of choice for serious bacterial infections. In a previous screen for novel genetic mediators affecting beta-lactam susceptibility, we discovered that deletion of ydgH, a conserved gene of unknown function, leads to increased resistance to beta-lactams, as well as increased susceptibility to detergent compounds. …”
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306
Characterization of Pancreatic Infections in Patients with Severe Acute Pancreatitis: A Retrospective Study from 2019 to 2023
Published 2025-01-01“…Multivariate logistic regression analysis revealed that septic shock, acute kidney injury, and tracheostomy were associated with a poor prognosis, whereas ICU length of stay, infected pancreatic necrosis, and tracheostomy were associated with multidrug-resistant bacterial infections in patients with severe or critical AP.Conclusion: The proportion of MDRO infections in patients with severe or critical AP was notably high, primarily involving multidrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii. …”
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307
Inflammatory Duodenal Polyposis Associated with Primary Immunodeficiency Disease: A Novel Case Report
Published 2017-01-01“…Agammaglobulinemia is a rare form of B-cell primary immunodeficiency disease characterized by reduced levels of IgG, IgA, or IgM and recurrent bacterial infections. Agammaglobulinemia is most commonly associated with diffuse nodular lymphoid hyperplasia. …”
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308
Infectious Keratitis: Secreted Bacterial Proteins That Mediate Corneal Damage
Published 2013-01-01“…Ocular bacterial infections are universally treated with antibiotics, which can eliminate the organism but cannot reverse the damage caused by bacterial products already present. …”
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309
Progress in the Study of Polymyxin Heteroresistance Molecular Mechanisms
Published 2024-11-01“…Polymyxins, a class of cyclic peptide antibiotics, have become the last line of defense against gram-negative bacterial infections as the number of multidrug-resistant bacteria continues to rise. …”
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310
Keratosis Palmoplantar-periodontopathy Syndrome – A Clinical Diagnostic Dilemma
Published 2024-12-01“…Patients also exhibit increased susceptibility to bacterial infections. Most of the cases are reported on account of homozygous mutations affecting cathepsin C (CTSC) gene, as both the alleles of cathepsin C gene are mutated. …”
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311
Insights into quorum sensing (QS): QS-regulated biofilm and inhibitors
Published 2020-11-01“…Hence, understanding the details of quorum sensing mechanisms, its phenotype regulation (biofilm), and QS inhibitors (which attenuate virulence/pathogenicity) may open a new avenue for controlling bacterial infections. …”
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312
Rooperol, an inhibitor of cytokine synthesis, decreases the respiratory burst in human and rat leukocytes and macrophages
Published 1997-01-01“…Thus rooperol may reduce some effects of excessive phagocytic activity and inflammatory reaction but by quenching free radicals production may also diminish the resistance to bacterial infections.…”
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313
Management of infants presenting with fever: a review of pan-London hospital guidelines and national guidelines
Published 2025-01-01“…Differentiating them from infants with serious bacterial infections can be challenging. We aimed to understand how febrile infants are managed across London, by analysing the management steps from local clinical practical guidelines (CPGs) and comparing them to the national guideline 143 (NG143). …”
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314
New directions in the fight against antibiotic resistance
Published 2024-12-01“…Antibiotic resistance represents one of the greatest challenges of modern medicine, having a significant impact on the treatment of bacterial infections. The development of antibiotic resistance renders standard treatments ineffective, putting patients' lives at risk and limiting available therapeutic options. …”
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315
Acute pyomyositis of the adductor magnus muscle involving the posterior and lateral thigh compartments: a case report of diagnosis and management
Published 2022-06-01“…Bacterial infection of skeletal muscle can lead to the formation of abscesses. …”
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316
An update on oral manifestations of systemic disorders in dogs and cats
Published 2025-01-01“…A wide range of systemic ailments may lead to lesions in the oral cavity, including immune-mediated diseases, adverse drug reactions, viral and bacterial infections, and metabolic and autoimmune diseases. …”
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317
Infection-Induced Vulnerability of Perinatal Brain Injury
Published 2012-01-01“…A common feature of many of these diseases is the systemic exposure of the neonate to bacterial infections that elicit brain inflammation. In recent years, the importance of innate immune receptors in newborn brain injury, the so-called Toll-like receptors, has been demonstrated. …”
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318
From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents
Published 2025-01-01“…Ciprofloxacin, a widely used second-generation fluoroquinolone for treating bacterial infections, has recently shown notable anticancer properties. …”
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319
Palmitoleic acid sensitizes vancomycin-resistant Staphylococcus aureus to vancomycin by outpacing the expression of resistance genes
Published 2025-01-01“…ABSTRACT The rise in antibiotic resistance limits the availability of antibiotics to treat bacterial infections. Despite this, antibiotic development pipelines remain sparse which makes using adjuvants to reverse antibiotic resistance a promising therapeutic strategy. …”
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320
Phage vB_Kpn_HF0522: Isolation, Characterization, and Therapeutic Potential in Combatting K1 Klebsiella pneumoniae Infections
Published 2025-02-01“…This study aimed to evaluate the efficacy of phage therapy in treating bacterial infections.Methods: Isolated phage vB_Kpn_HF0522 and phage morphology were observed using transmission electron microscopy. …”
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