Showing 41 - 60 results of 692 for search '"autophagy"', query time: 0.07s Refine Results
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    Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction by Zhendong Feng, Han Xue Jiang, Huiyang Chen, Yu Ning Liu, Yahui Wang, Rui Bing Yang, Xueting Han, Chen Hui Xia, Ze Bing Zhu, Hongcai Shang, Aiming Wu, Wei Jing Liu

    Published 2020-01-01
    “…Understanding the multifactorial changes involved in the kidney and heart after acute myocardial infarction (AMI) is prerequisite for further mechanisms and early intervention, especially autophagy changes. Here, we discussed the role of adaptive autophagy in the heart and kidney of rats with AMI. …”
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    Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection. by Jacques Augenstreich, Anna T Phan, Charles N S Allen, Anushka Poddar, Hanzhang Chen, Lalitha Srinivasan, Volker Briken

    Published 2025-01-01
    “…Autophagy plays a crucial role in the host response to Mycobacterium tuberculosis (Mtb) infection, yet the dynamics and regulation of autophagy induction on Mtb-containing vacuoles (MCVs) remain only partially understood. …”
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    A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease by Patricia Gómez-Suaga, Elena Fdez, Marian Blanca Ramírez, Sabine Hilfiker

    Published 2012-01-01
    “…Apart from cytotoxicity, changes in autophagy have been consistently reported in the context of G2019S mutant LRRK2. …”
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    Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy by Constanza J. Cortes, Kefeng Qin, Eric M. Norstrom, William N. Green, Vytautas P. Bindokas, James A. Mastrianni

    Published 2013-01-01
    “…In autophagy deficient (ATG5−/−) mouse embryonic fibroblasts, or in normal cells treated with the autophagy-inhibitor 3-MA, Mut-PrP colocalization with lysosomes was reduced to a similar extent. …”
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    FTO Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Apoptosis and Autophagy by Pi-Xiao Wang, Ling Zhu, Mei Xiang, Rixin Zhang, Xiaolin Zheng, Zhi Zheng, Kai Li

    Published 2025-01-01
    “…Conclusion: FTO could act as a protective effector during hepatic IRI, associated with decreased apoptosis and autophagy. FTO-mediated m6A demethylation modification may be an important therapeutic target for hepatic IRI.…”
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    Autophagy Mediates MMP-2 Expression in Glaucomatous Trabecular Meshwork Cells by Yan-Ling Xiao, Xiao-Rui Wang, Kejing Ye, Wan-Zhu Chen, Bing-Ru Zheng, Yi-Hong Huang, Yu-Yu Wu

    Published 2022-01-01
    “…Cellular mRNA and protein were measured at different 3-MA concentrations and starvation time periods. The level of autophagy was accessed by monodansylcadaverine fluorescent staining and expression of specific autophagy-related genes, light chain 3 (LC3), and Beclin1. …”
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    Oscillatory autophagy induction is enabled by an updated AMPK-ULK1 regulatory wiring. by Orsolya Kapuy, Marianna Holczer, Luca Csabai, Tamás Korcsmáros

    Published 2024-01-01
    “…Autophagy-dependent survival relies on a crucial oscillatory response during cellular stress. …”
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    METTL3 regulates autophagy of hypoxia-induced cardiomyocytes by targeting ATG7 by Linnan Li, Hao Cheng, Yufei Zhou, Di Zhao, Xiaoxue Zhang, Yajun Wang, Jianying Ma, Junbo Ge

    Published 2025-02-01
    “…METTL3 negatively regulated autophagy in cardiomyocytes under ischemia and hypoxia conditions. …”
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    The Synergistic Effects of Celastrol in combination with Tamoxifen on Apoptosis and Autophagy in MCF-7 Cells by Lijun Wang, Luqun Tang, Chengyun Yao, Chunyan Liu, Yongqian Shu

    Published 2021-01-01
    “…Moreover, the distribution of LC3 was monitored by immunofluorescence, and the changes in the LC3II and P62 levels detected by western blot analysis suggested that celastrol in combination with tamoxifen triggered autophagy. Furthermore, the decrease in p-Akt and p-mTOR in MCF-7 cells, along with the increase in the autophagy marker proteins LC3II and P62, suggested that the Akt/mTOR pathway might be involved in the triggering of cell autophagy by the combination treatment. …”
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    Targeting secretory autophagy in solid cancers: mechanisms, immune regulation and clinical insights by Xinyu Li, Haiying Zhao

    Published 2025-02-01
    “…Abstract Secretory autophagy is a classical form of unconventional secretion that integrates autophagy with the secretory process, relying on highly conserved autophagy-related molecules and playing a critical role in tumor progression and treatment resistance. …”
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