Showing 181 - 200 results of 692 for search '"autophagy"', query time: 0.06s Refine Results
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    Dipeptidyl-Peptidase 4 Inhibitor Sitagliptin Ameliorates Hepatic Insulin Resistance by Modulating Inflammation and Autophagy in ob/ob Mice by Wenbin Zheng, Jing Zhou, Shasha Song, Wen Kong, Wenfang Xia, Lulu Chen, Tianshu Zeng

    Published 2018-01-01
    “…This study was aimed at investigating the effect of sitagliptin on hepatic steatosis, insulin resistance, inflammation, and autophagy and exploring the underlying molecular mechanism. …”
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    Article
  6. 186

    FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage by Fan Wang, Yue Xu, Yajie Wang, Qian Liu, Yanan Li, Weiwei Zhang, Huiming Nong, Junhong Zhang, Hao Zhao, Huaqian Yang, Lingchuan Guo, Jianfeng Li, Jianfeng Li, Hong Li, Qianqian Yang

    Published 2025-01-01
    “…IntroductionCochlear spiral ganglion neurons (SGNs) could be damaged by ototoxic drug, cisplatin (Cis), during which process autophagy was involved. FAM134B, the first detected endoplasmic reticulum autophagy (ER-phagy) receptor, plays an important part in the dynamic remodelling of the ER, the mutation of which affects sensory and autonomic neurons. …”
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    Article
  7. 187

    TEEG Induced A549 Cell Autophagy by Regulating the PI3K/AKT/mTOR Signaling Pathway by Lu Shi, Yijun Tu, Yu Xia, Siqi Ye, Chaozhi Ma, Yanwen Liu, Pengtao You

    Published 2019-01-01
    “…Autophagy-associated proteins were examined by Western blot analysis. …”
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    Article
  8. 188

    Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR-γ Functional Module of Autophagy in Rheumatoid Arthritis by Weiyan Wang, Chunling Li, Zhiyi Zhang, Yue Zhang

    Published 2019-01-01
    “…Dysregulated autophagy leads to autoimmune diseases including rheumatoid arthritis (RA). …”
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    Article
  9. 189

    Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy by Pingting Ye, Lei Feng, Dan Zhang, Ruihao Li, Yixuan Wen, Xiaohan Tong, Shuo Shi, Chunyan Dong

    Published 2023-01-01
    “…Furthermore, the results show that activation of 5′AMP-activated protein kinase (AMPK) by metformin enhances cell autophagy in senescent hBMSCs. These findings suggest that metformin exerts antiaging function within the low concentration range by enhancing autophagy and exhibits potential benefits for clinical stem cell therapy by ameliorating the ex vivo replicative senescence of hBMSCs.…”
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  10. 190

    Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway by Hui Huang, Qun Huang, Jing Wang, Wanjie Wang, Yanlin Zheng

    Published 2025-01-01
    “…The autophagy-promoting effect of TGF-β2 on APRE-19 cells was further enhanced by Hirudo extract. …”
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    RIPK2-Mediated Autophagy and Negatively Regulated ROS-NLRP3 Inflammasome Signaling in GMCs Stimulated with High Glucose by Chenlin Gao, Jiao Chen, Fang Fan, Yang Long, Shi Tang, Chunxia Jiang, Jiying Wang, Youhua Xu, Yong Xu

    Published 2019-01-01
    “…In this study, we aimed to explore the mechanisms mediated by RIPK2 in autophagy and the relationship with ROS-NLRP3 of DN, by investigating the levels of RIPK2 and autophagy in glomerular mesangial cells (GMCs) stimulated with high glucose. …”
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    Qingfei Tongluo Mixture Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis through mTOR-Dependent Autophagy in Rats by Shuyu Ge, Zhenghong Guo, Ting Xiao, Pingping Sun, Bo Yang, Yin Ying

    Published 2024-01-01
    “…The expression changes of pulmonary fibrosis and autophagy marker proteins are attenuated by QFTL. Furthermore, the autophagy inhibitor CQ significantly reversed the downward trend in HYP levels and α-SMA protein expression, which QFTL improved in BLM-induced pulmonary fibrosis rats. …”
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    Inhibition of Autophagy in Heat-Stressed Sperm of Adult Mice: A Possible Role of Catsper1, 2 Channel Proteins by Malihe Soltani, Majid Rahmati, Mohammad Reza Nikravesh, Shahin Saeedi Nejat, Mahdi Jalali

    Published 2023-01-01
    “…Autophagy is influenced by oxidative stress, disturbances of calcium homeostasis, and hyperthermia conditions. …”
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    Effect of Rho-Kinase and Autophagy on Remote Ischemic Conditioning-Induced Cardioprotection in Rat Myocardial Ischemia/Reperfusion Injury Model by Jie Gao, Feng Min, Shasha Wang, Heng Lv, Huan Liang, Ben Cai, Xianjie Jia, Qin Gao, Ying Yu

    Published 2022-01-01
    “…This study investigated the mechanism of Rho-kinase-mediated autophagy in RIC. Methods. Sixty male Sprague–Dawley rats were randomly divided into six groups: sham, I/R, RIC, I/R+fasudil, RIC+wortmannin, and RIC+fasudil+wortmannin. …”
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