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1441
Assessment of the relationship between urinary iodine level and thyroid dysfunction among children in South India- A case-control study
Published 2024-07-01“…FNAC and autoantibody reports confirmed 66% of autoimmune thyroiditis found in the case group. Conclusion: Higher levels of urinary iodine excretion suggest the consumption of excess iodine intake in children. …”
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1442
The Protective Effects of 18β-Glycyrrhetinic Acid on Imiquimod-Induced Psoriasis in Mice via Suppression of mTOR/STAT3 Signaling
Published 2020-01-01“…Psoriasis is recognized as an autoimmune and inflammatory dermatosis, which is estimated to affect 2-3% of the population worldwide. 18β-Glycyrrhetinic acid (GA), one of the main ingredients of Licorice (Glycyrrhiza glabra L.), has been shown to have numerous pharmacological effects such as antioxidative, antitumor, and anti-inflammatory activities. …”
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1443
Biosimilars in Focus: Evaluating Their Role Compared to Adalimumab in Clinical Practice
Published 2025-01-01“…Introduction and Purpose: Adalimumab, a TNF-α inhibitor, is a cornerstone treatment for autoimmune and inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease. …”
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1444
Upregulation of FOXO3 in New-Onset Type 1 Diabetes Mellitus
Published 2020-01-01“…In conclusion, overexpression of FOXO3 is correlated with the ongoing islet autoimmune destruction and might suggest a potential role for this gene in the pathogenesis of type 1 diabetes mellitus.…”
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1445
Effects of different doses of glucose and fructose on central metabolic pathways and intercellular wireless communication networks in humans
Published 2024-07-01“…Therefore, excessive intake of fructose should be reduced to avoid excessive inflammatory responses, allergic reactions and autoimmune diseases.…”
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1446
Impact of Likelihood Ratios of Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide Antibody in Clinical Diagnosis of Rheumatoid Arthritis by Two Available Platforms
Published 2025-01-01“…<b>Background/Objectives</b>: Rheumatoid arthritis (RA) is one of the most prevalent autoimmune diseases, characterized by an articular and extra-articular involvement, where autoantibodies, such as rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibodies (ACPAs), are important biomarkers for the diagnosis. …”
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1447
Daptomycin-Induced Acute Eosinophilic Pneumonia: Late Onset and Quick Recovery
Published 2017-01-01“…It is a distinct entity from atopic diseases and autoimmune, parasitic, or fungal infections that can also cause pulmonary eosinophilia. …”
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1448
An Innovative Method to Identify Autoantigens Expressed on the Endothelial Cell Surface: Serological Identification System for Autoantigens Using a Retroviral Vector and Flow Cytom...
Published 2013-01-01“…SARF is useful for specific identification of autoantigens expressed on the cell surface, and identification of such interactions of the cell-surface autoantigens and pathogenic autoantibodies may enable the development of more specific intervention strategies in autoimmune diseases.…”
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1449
Effects of Splenectomy on Spontaneously Chronic Pancreatitis in aly/aly Mice
Published 2010-01-01“…In this study, we used splenectomized aly/aly mice to elucidate the effects of secondary lymphoid organs in the development of aly/aly autoimmune pancreatitis. Methods. Forty-eight 10-week-old aly/aly mice were divided into two groups for splenectomy and sham operation. …”
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1450
Insulin Independence in Newly Diagnosed Type 1 Diabetes Patient following Fenofibrate Treatment
Published 2020-01-01“…Fenofibrate reverses and prevents autoimmune diabetes in nonobese diabetic (NOD) mice by increasing the amount of the sphingolipid sulfatide in islets. …”
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1451
Disease-Specific Autoantibodies Induce Trained Immunity in RA Synovial Tissues and Its Gene Signature Correlates with the Response to Clinical Therapy
Published 2020-01-01“…We conclude that RA-specific autoantibodies can train monocytes in the inflamed lesion as early as the asymptomatic stage, which may not merely improve understanding of disease progression but may also suggest therapeutic and/or preventive strategies for autoimmune diseases.…”
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1452
When herpes zoster is not herpes: A case of statin-induced myopathy complicated by drug allergies
Published 2025-01-01“…After discontinuing atorvastatin and clindamycin, her CK levels improved, and subsequent testing confirmed the presence of anti-HMG-CoA reductase antibodies, establishing a diagnosis of statin-induced autoimmune necrotizing myopathy. This case underscores the importance of detailed patient histories and the need to consider drug-induced hypersensitivity reactions in immunocompromised individuals. …”
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1453
Anti-NMDA Receptor Encephalitis in a Patient with Previous Psychosis and Neurological Abnormalities: A Diagnostic Challenge
Published 2015-01-01“…Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder characterized by IgG autoantibodies directed against the NR1 subunit of the NMDA glutamate receptor. …”
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1454
Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis
Published 2012-01-01“…Recent reviews on PADs have focused on their role in autoimmune diseases. Here, we will discuss the potential role of PADs in tumor progression and tumor-associated inflammation. …”
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1455
Peripherally Embolizing Aortic Thrombus: The Work-Up, Management, and Outcome of Primary Aortic Thrombus
Published 2019-01-01“…Computed tomography (CT) revealed an intraluminal polypoid filling defect arising from the isthmus of the aorta projecting into the proximal descending aorta and findings consistent with infarction of the spleen and right kidney. Infectious, autoimmune, hematologic, and oncologic work-up were all unyielding. …”
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1456
Calcinosis Universalis of the Elbow: A Rare Case with Classical Presentation
Published 2015-01-01“…Juvenile Dermatomyositis (JDM) is a rare autoimmune disease in children and adolescents. In these patients calcinosis might be the most characteristic symptom. …”
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1457
Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study
Published 2020-01-01“…Among 238 PHPT patients undergoing parathyroidectomy (PTX) between 2002 and 2017, 128 were affected also by a benign thyroid disease, namely, goiter in 118 (76 multinodular (MNG) and 42 uninodular (UNG)), autoimmune thyroiditis in 10, and hyperthyroidism in 21. …”
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1458
Unravelling the TCRβ repertoire: a key to unlocking the immunopathogenesis and precision medicine in SLE
Published 2025-01-01“…Objectives SLE is a multifaceted autoimmune disorder with a complex pathogenesis involving genetic, environmental and hormonal factors, which converge on immune dysregulation. …”
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1459
Lethal End of Spectrum of Clots-Thrombotic Storm
Published 2018-01-01“…Usually, younger female patients are affected; in some patients, there is an association with an autoimmune disorder like lupus erythematosus, and they show evidence of antiphospholipid antibodies or other phenotypic expressions of anticoagulation disorders. …”
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1460
Bioinformatic analysis of ferroptosis related biomarkers and potential therapeutic targets in vitiligo
Published 2025-01-01“…Abstract Vitiligo is a complex autoimmune skin disorder characterized by depigmentation and immune dysregulation. …”
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