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1141
Oxidative stress: an overview of past research and future insights
Published 2024-12-01“…The obtained findings suggest that many diseases are linked to OS, including diabetes mellitusinflammation, cancers, autoimmune disorders and neurodegenerative diseases. …”
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1142
False Positive B-Cells Crossmatch after Prior Rituximab Exposure of the Kidney Donor
Published 2016-01-01“…An unexpected positive crossmatch may be obtained in recipients with an autoimmune disease or preexisting antibodies not detected by single-antigen bead array due to complement interference or who have been previously treated by desensitization protocols such as rituximab, antithymocyte globulin, or intravenous immunoglobulins. …”
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1143
C4d Deposition in Fetal Vessels of the Placenta in Neonatal Lupus Syndrome
Published 2019-01-01“…Neonatal lupus syndrome (NLS) is a rare, passively acquired autoimmune syndrome caused by maternal autoantibodies. …”
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1144
Pulmonary Alveolar Proteinosis in Setting of Inhaled Toxin Exposure and Chronic Substance Abuse
Published 2018-01-01“…PAP is categorized into three types: hereditary, autoimmune, and secondary. We report a case of secondary PAP in a 47-year-old man, whose risk factors include occupational exposure to inhaled toxins, especially aluminum dust, the use of anabolic steroids, and alcohol abuse, which in mice leads to alveolar macrophage dysfunction through a zinc-dependent mechanism that inhibits granulocyte macrophage-colony stimulating factor (GM-CSF) receptor signalling. …”
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1145
Design and synthesis of amino-substituted N-arylpiperidinyl-based inhibitors of the (immuno)proteasome
Published 2023-09-01“…The constitutive proteasome and the immunoproteasome represent validated targets for pharmacological intervention in the context of various diseases, such as cancer, inflammation, and autoimmune diseases. The development of novel chemical scaffolds of non-peptidic nature, capable of inhibiting different catalytically active subunits of both isoforms, is a viable approach against these diseases. …”
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1146
Systemic Treatments for Noninfectious Vitreous Inflammation
Published 2013-01-01“…Vitreous inflammation, or vitritis, may result from many causes, including both infectious and noninfectious, including rheumatologic and autoimmune processes. Vitritis is commonly vision threatening and has serious sequelae. …”
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1147
Hidden Hematologic Disease in Trauma Patients: A Report of Two Cases
Published 2020-06-01“…In this report, we present cases of two hematologic disorders found in trauma patients: autoimmune hemolytic anemia induced by systemic lupus erythematosus and myelodysplastic syndrome.…”
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1148
Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study
Published 2019-01-01“…Psoriasis, an autoimmune disease, affects a vast number of peoples around the world. …”
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1149
Complement Diagnostics: Concepts, Indications, and Practical Guidelines
Published 2012-01-01“…Aberrations in the complement system have been shown to be direct or indirect pathophysiological mechanisms in a number of diseases and pathological conditions such as autoimmune disease, infections, cancer, allogeneic and xenogeneic transplantation, and inflammation. …”
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1150
Unfolded protein responses in T cell immunity
Published 2025-01-01“…Emerging evidence suggests that the UPR may be a potential therapeutic target for diseases characterized by T cell dysfunction, such as autoimmune disorders and cancer. Further research is needed to elucidate the complex interactions between ER stress, the UPR, and T cell immunity to develop novel therapeutic strategies for T cell-associated diseases.…”
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1151
Recurrent Thrombotic Vasculopathy in a Former Cocaine User
Published 2015-01-01“…Further workup did not reveal any other, autoimmune or infectious, etiology of this clinical presentation. …”
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1152
Profound Autonomic Instability Complicated by Multiple Episodes of Cardiac Asystole and Refractory Bradycardia in a Patient with Anti-NMDA Encephalitis
Published 2016-01-01“…Anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDARE) is autoimmune encephalitis primarily affecting young adults and children. …”
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1153
Antineutrophil Cytoplasmic Antibody Induction due to Infection: A Patient with Infective Endocarditis and Chronic Hepatitis C
Published 2016-01-01“…In the case of infective endocarditis, patients may present with multisystem disturbances resembling an autoimmune process, cases that may be rendered even trickier to diagnose in the face of a positive ANCA. …”
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1154
A glimpse into the black box of celiac disease complications: a case report with a rare presentation
Published 2021-06-01“…Many cases of celiac disease in children who are not diagnosed and treated properly suffer from a plethora of complications due to malabsorption and concurrent autoimmune reactions that affect mainly but are not limited to the endocrine system. …”
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1155
Protection of Fecal Microbiota Transplantation in a Mouse Model of Multiple Sclerosis
Published 2020-01-01“…To evaluate the viability of FMT for MS treatment and its impact on MS pathology, we tested FMT in mice with experimental autoimmune encephalomyelitis (EAE), a mouse model of MS. …”
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1156
Immunoregulation of NKT Cells in Systemic Lupus Erythematosus
Published 2015-01-01“…Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with different variety of clinical manifestations. …”
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1157
T Lymphocyte Autoreactivity in Inflammatory Mechanisms Regulating Atherosclerosis
Published 2012-01-01“…These self-molecules activate autoimmune reactions mainly characterized by the production of Th1 cytokines, thus sustaining the inflammatory mechanisms involved in endothelial dysfunction and plaque development. …”
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1158
A Case of Relapsing Polychondritis Initiating with Unexplained Fever
Published 2016-01-01“…Relapsing polychondritis (RP) is a rare autoimmune disease affecting the multiple organ system. …”
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1159
Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature
Published 2021-01-01“…Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by chronic seropositive symmetrical inflammatory polyarthritis with numerous extra-articular manifestations. …”
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1160
Salivary Cytokines as Potential Diagnostic Biomarkers for Systemic Lupus Erythematosus Disease
Published 2021-01-01“…Systemic lupus erythematosus (SLE) is a complex autoimmune inflammatory disease characterized by an unknown etiology and a highly variable clinical presentation. …”
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