Role of Neutrophils in Psoriasis by Wen-Ming Wang, Hong-Zhong Jin

“…Emerging evidences have demonstrated that neutrophils may play a role in autoimmune diseases. The neutrophil-to-lymphocyte ratio (NLR), the activity of neutrophils, and the number of NETotic cells were significantly higher in psoriasis patients compared to healthy controls. …”
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Case Report: Diagnostic itinerary of a male case of juvenile-onset systemic lupus erythematosus in Bouake by Aissata Doucoure Traore, Aissata Doucoure Traore, Joseph Kan Enock Koffi, Joseph Kan Enock Koffi, Christ Ziahy Reine Marie Koffi, Christ Ziahy Reine Marie Koffi, Konan Joe Clovis Yao, Konan Joe Clovis Yao, Jean Jacque Goua, Jean Jacque Goua, Ehaulier Soh Christian Kouakou, Ehaulier Soh Christian Kouakou, Weu Melanie Tia, Weu Melanie Tia, Felix Jean Claude Daboiko, Felix Jean Claude Daboiko

“…Juvenile-onset systemic lupus erythematosus (JLES) is an autoimmune disease of unknown aetiology. It is more common in girls but can occur in boys. …”
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Diagnostic Dilemma of Disseminated Histoplasmosis Mimicking Hemophagocytosis Lymphohistiocytosis in Patient with Rheumatoid Arthritis on Anti-TNF Therapy: Case Report and Review of... by Saurav Suman, Aleksander Lenert

“…Tumor necrosis factor inhibitors (TNFi) have become the cornerstone for the treatment of rheumatoid arthritis and other systemic autoimmune conditions. However, these biologic DMARDs can lead to various opportunistic infections such as viral infection, tuberculosis, and histoplasmosis. …”
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Lipschütz Genital Ulceration as Initial Manifestation of Primary Sjögren’s Syndrome by Filipa de Castro Coelho, Maria Amaral, Lúcia Correia, Maria João Nunes Campos, Tereza Paula, Augusta Borges, Jorge Borrego

“…Reactive acute genital ulcers (Lipschütz ulcers) should be considered as a possible manifestation of many autoimmune/inflammatory disorders, beyond the classic associations such as Behçet’s syndrome or Crohn’s disease.…”
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Combined Cerebellar and Spinal Cord Deficits Caused by an Underlying Gynecologic Malignancy by Tamer Othman, Moshe-Samuel Hendizadeh, Ritika Vankina, Susan Park, Phyllis Kim

“…Paraneoplastic cerebellar degeneration (PCD) is an uncommon autoimmune disorder targeting antigens within the nervous system and is usually associated with an underlying malignancy. …”
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An Unusual Case of Systemic Lupus Erythematosus and Hemophagocytic Syndrome by Saika Sharmeen, Nazia Hussain

“…Hemophagocytic syndrome (HS) or hemophagocytic lymphohistiocytosis (HLH) is an immune mediated phenomenon that can occur in the setting of an autoimmune disease, chronic immunosuppression, malignancy, or infection. …”
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From diagnosis to treatment: exploring the mechanisms underlying optic neuritis in multiple sclerosis by Bin Tong, Xin Zhang, Haijian Hu, Huayi Yang, Xifeng Wang, Maolin Zhong, Fan Yang, Fuzhou Hua

“…Abstract Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system, commonly causing sensory disturbances, motor weakness, impaired gait, incoordination and optic neuritis (ON). …”
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Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR-γ Functional Module of Autophagy in Rheumatoid Arthritis by Weiyan Wang, Chunling Li, Zhiyi Zhang, Yue Zhang

“…Dysregulated autophagy leads to autoimmune diseases including rheumatoid arthritis (RA). …”
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Human Mesenchymal Stem Cells: The Present Alternative for High-Incidence Diseases, Even SARS-Cov-2 by Karen J. Juárez-Navarro, Eduardo Padilla-Camberos, Néstor Fabián Díaz, Ariel Miranda-Altamirano, N. Emmanuel Díaz-Martínez

“…Nowadays, there are more than a thousand registered clinical trials related to MSC application around the world, highlighting MSC role on difficult-to-treat high-incidence diseases such as the current COVID-19, HIV infections, and autoimmune and metabolic diseases. Here, we summarize a general overview of MSCs and their therapeutic mechanisms; also, we discuss some of the novel clinical trial protocols and their results as well as a comparison between the number of registries, countries, and search portals.…”
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Steroid-Responsive Encephalopathy Associated with Thyroiditis (SREAT): A Case Report of Saving a Young Female Life by Abdelrahman Mahmoud Senosy

“…Hashimoto’s encephalopathy (HE), a rare autoimmune disorder associated with thyroiditis, is a condition with no definitive cause. …”
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From pathogenesis to new developments in treatment of primary progressive multiple sclerosis. Literature review by A. Juknelytė, Ž. Vaičekauskytė, D. Mickevičienė, R. Balnytė

“… Multiple sclerosis (MS) is characterised as a chronic autoimmune inflammatory disease of the central nervous system (CNS) affecting more than 2.3 million people all over the world. …”
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Intricating connections: the role of ferroptosis in systemic lupus erythematosus by Guowang Zhao, Xinghai Li, Ying Zhang, Ying Zhang, Xingzi Wang, Li Deng, Juan Xu, Shumei Jin, Zan Zuo, Zan Zuo, Linting Xun, Linting Xun, Mei Luo, Mei Luo, Fan Yang, Jialong Qi, Jialong Qi, Jialong Qi, Jialong Qi, Ping Fu

“…Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease with multiple tissue damage. However, the pathology remains elusive, and effective treatments are lacking. …”
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Programmed Cell Death Pathways in the Pathogenesis of Systemic Lupus Erythematosus by Fangyuan Yang, Yi He, Zeqing Zhai, Erwei Sun

“…Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by excessive inflammatory and immune responses and tissue damage. …”
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Paroxysmal Cold Hemoglobinuria in an Adult with Respiratory Syncytial Virus by Ryan Leibrandt, Kenneth Angelino, Monique Vizel-Schwartz, Ilan Shapira

“…Paroxysmal cold hemoglobinuria (PCH) is a rare form of cold autoimmune hemolytic anemia first discovered in the early 20th century in adults with tertiary syphilis. …”
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Incidental Finding of Thyroid Tuberculosis by Operation for Graves’ Disease: A Rare Case Presentation by Zineb El Azime, Samira Handa, Ghita Bourkadi, Hayat Aynaou, Houda Salhi, Hanan El Ouahabi

“…This article reports a distinctive case of thyroid tuberculosis coexisting with Graves’ disease, one of the autoimmune thyroid diseases. A 33-year-old female presented symptoms consistent with hyperthyroidism and bilateral exophthalmos. …”
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Relapsing Polychondritis by Beata Sosada, Katarzyna Loza, Ewelina Bialo-Wojcicka

“…Although the cause remains unknown, the etiology is suspected to be autoimmune. We describe a case of a 31-year-old woman with a four-month history of bilateral auricular and nasal chondritis. …”
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Pulmonary Limited MPO-ANCA Microscopic Polyangiitis and Idiopathic Lung Fibrosis in a Patient with a Diagnosis of IgA Nephropathy by Alwin Tilanus, Patricia Van der Niepen, Caroline Geers, Karl Martin Wissing

“…This unique case illustrates the diagnostic and therapeutic challenges of an unusual presentation of microscopic polyangiitis presenting first as isolated kidney disease with recurrence in the form of pneumonitis without renal involvement, in association with renal IgA deposits and ITP as coexisting autoimmune conditions.…”
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The Mechanisms Underlying Chronic Inflammation in Rheumatoid Arthritis from the Perspective of the Epigenetic Landscape by Yasuto Araki, Toshihide Mimura

“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that is characterized by synovial hyperplasia and progressive joint destruction. …”
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Enhancing the effectiveness of immunotherapy in rheumatoid arthritis by delaying immunosenescence triggered by fibroblast-like synoviocytes by Li Zhang, Yang Luo, Hai-Li Shen

“…Abstract Rheumatoid arthritis (RA) is a prevalent autoimmune disorder primarily targeting the diarthrodial joints. …”
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Pericardial Tamponade: An Uncommon Clinical Presentation in cANCA Related Vasculitis and Glomerulonephritis in Association with Very High Titres of ANA by Amaresh Vanga, Amna Z. Rana, Jolanta Kowalewska, Harlan Rust

“…ANCA (anti-neutrophil cytoplasmic antibody) vasculitides are systemic autoimmune diseases in which anti-neutrophilic cytoplasmic antibodies activate primed neutrophils, thereby generating an inflammatory cascade resulting in the damage of small sized blood vessels in various organs of the body, including the heart. …”
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