Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy by Motoko Sasaki, Yasuni Nakanuma

“…Primary biliary cirrhosis (PBC) is characterized by antimitochondrial autoantibodies (AMAs) in patients' sera and histologically by chronic nonsuppurative destructive cholangitis in small bile ducts, eventually followed by extensive bile duct loss and biliary cirrhosis. The autoimmune-mediated pathogenesis of bile duct lesions, including the significance of AMAs, triggers of the autoimmune process, and so on remain unclear. …”
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The Spectrum of Anti-Chromatin/Nucleosome Autoantibodies: Independent and Interdependent Biomarkers of Disease by Sonal Mehra, Marvin J. Fritzler

“…This review will focus on immunoassays that utilize chromatin components, their clinical relationships, and newer evidence implicating HMG proteins and DNA neutrophil extracellular traps (NETs) as important players in systemic autoimmune rheumatic diseases.…”
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Proteomic Analyses of the Vitreous Humour by Martina Angi, Helen Kalirai, Sarah E. Coupland, Bertil E. Damato, Francesco Semeraro, Mario R. Romano

“…Recent proteomic studies on the VH from animal models of autoimmune uveitis have identified new signalling pathways associated to autoimmune triggers and intravitreal inflammation. …”
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CD154: An Immunoinflammatory Mediator in Systemic Lupus Erythematosus and Rheumatoid Arthritis by Nada Alaaeddine, Ghada S. Hassan, Daniel Yacoub, Walid Mourad

“…Systemic lupus erythematosus and rheumatoid arthritis are two major chronic inflammatory autoimmune diseases with significant prevalence rates among the population. …”
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Successful Management of Acquired Hemophilia A Associated with Bullous Pemphigoid: A Case Report and Review of the Literature by Quentin Binet, Catherine Lambert, Laurine Sacré, Stéphane Eeckhoudt, Cedric Hermans

“…About half the cases are associated with pregnancy, postpartum, autoimmune diseases, malignancies, or adverse drug reactions. …”
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Coexisting Situs Inversus Totalis and Immune Thrombocytopenic Purpura by Kemal Gundogdu, Fatih Altintoprak, Mustafa Yener Uzunoğlu, Enis Dikicier, İsmail Zengin, Orhan Yağmurkaya

“…Immune thrombocytopenic purpura is an autoimmune disease with destruction of thrombocytes. …”
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Clinical Characteristics of Concomitant Systemic Lupus Erythematosus and Primary Biliary Cirrhosis: A Literature Review by Toru Shizuma

“…Although autoimmune diseases often coexist, concomitant cases of systemic lupus erythematosus (SLE) and primary biliary cirrhosis (PBC) are uncommon. …”
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IgG4 Cholangiopathy by Yoh Zen, Yasuni Nakanuma

“…Most cases are associated with autoimmune pancreatitis, an important diagnostic clue. …”
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Role of Adaptive Immunity in Alcoholic Liver Disease by Emanuele Albano

“…Altogether these results suggest that allo- and autoimmune reactions triggered by oxidative stress might contribute to hepatic inflammation during the progression of ALD.…”
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Mycoplasma Pneumonia: An Unrecognized Cause of Fever of Unknown Origin in an Adult by Fatima Ali-Ahmed, Alexandra Halalau

“…She had no respiratory symptoms or family history of autoimmune diseases. A chest X-ray was negative for pneumonia or hilar adenopathy. …”
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Helminth Parasites and the Modulation of Joint Inflammation by Chelsea E. Matisz, Jason J. McDougall, Keith A. Sharkey, Derek M. McKay

“…There is an urgent need to develop better therapeutics for autoimmune and autoinflammatory diseases, of which musculoskeletal disorders such as rheumatoid arthritis are particularly prevalent and debilitating. …”
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Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence by Lyudmila V. Savvateeva, Svetlana I. Erdes, Anton S. Antishin, Andrey A. Zamyatnin

“…Celiac disease (CD) is an autoimmune enteropathy triggered by the ingestion of dietary gluten from some cereals mainly in individuals carrying the HLA-DQ2 and/or HLA-DQ8 haplotypes. …”
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Automated Evaluation of Crithidia luciliae Based Indirect Immunofluorescence Tests: A Novel Application of the EUROPattern-Suite Technology by Stefan Gerlach, Kai Affeldt, Lena Pototzki, Christopher Krause, Jörn Voigt, Johanna Fraune, Kai Fechner

“…Systemic lupus erythematosus (SLE) is a severe rheumatic autoimmune disease with various clinical manifestations. …”
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Infectious scleritis: a review of etiologies, clinical features, and management strategies by Supriya Sharma, Jay U. Sheth, Somasheila I. Murthy, Somasheila I. Murthy

“…The initial clinical presentation may often resemble autoimmune scleritis, thus resulting in a delayed diagnosis and poorer outcomes. …”
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The Videofluorographic Swallowing Study in Rheumatologic Diseases: A Comprehensive Review by Ambra Di Piazza, Federica Vernuccio, Massimo Costanzo, Laura Scopelliti, Dario Picone, Federico Midiri, Francesco Salvaggi, Francesco Cupido, Massimo Galia, Sergio Salerno, Antonio Lo Casto, Massimo Midiri, Giuseppe Lo Re, Roberto Lagalla

“…Autoimmune connective tissue diseases are a heterogeneous group of pathologies that affect about 10% of world population with chronic evolution in 20%–80%. …”
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Role of Cytokines and Toll-Like Receptors in the Immunopathogenesis of Guillain-Barré Syndrome by Kishan Kumar Nyati, Kashi Nath Prasad

“…Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system, mostly triggered by an aberrant immune response to an infectious pathogen. …”
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Occlusion of Internal Carotid Artery in Kimura's Disease by Tomonori Tamaki, Node Yoji

“…We suspected that occlusion of this patient's internal carotid artery may be caused by the autoimmune mechanism that underlies Kimura's disease.…”
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Primary biliary cirrhosis: clinical and laboratory criteria of diagnostics and up-to-date treatment by L. Yu. Il’chenko, V. I. Reshetn’yak

“…PBC is organ-specific autoimmune liver disease affecting predominantly women that is characterized by chronic progressing destruction of intrahepatic bile ducts with portal inflammation, resulting in development of liver cirrhosis (LC). …”
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Immune Tolerance Regulation Is Critical to Immune Homeostasis by Lei Han, Tianxiang Wu, Qin Zhang, Anning Qi, Xiaohui Zhou

“…Its induction or elimination plays a significant role in autoimmune diseases, organ transplantation, and cancer therapy, markedly impacting various major diseases in modern clinical practice. …”
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Serological Immunoglobulin-Free Light Chain Profile in Myasthenia Gravis Patients by Umberto Basile, Mariapaola Marino, Cecilia Napodano, Krizia Pocino, Paolo Emilio Alboini, Francesca Gulli, Amelia Evoli, Carlo Provenzano, Emanuela Bartoccioni

“…Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction with antibodies (abs) targeting the acetylcholine receptor (AChR) or the muscle-specific tyrosine kinase (MuSK), inducing muscle weakness and excessive fatigability. …”
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