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701
NF-κB-94ins/del ATTG Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia
Published 2018-01-01“…The NLRP3 inflammasome plays important roles in the pathogenesis of autoimmune diseases. However, the role of the NLRP3 inflammasome in the pathophysiology of immune thrombocytopenia (ITP) remains unclear. …”
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702
Multiple Immunosuppressive Effects of CpG-c41 on Intracellular TLR-Mediated Inflammation
Published 2017-01-01“…A growing body of literature suggests that most chronic autoimmune diseases are associated with inappropriate inflammation mediated by Toll-like receptor (TLR) 3, TLR7/8, or TLR9. …”
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703
Immunization‐related complex regional pain syndrome: A systematic review of case reports
Published 2024-12-01“…Outcomes of interest include type of vaccination, patient age, patient sex, time to symptom onset, and medical history including but not limited to previous autoimmune diseases, psychological illness, physical tissue trauma, and neurological disease. …”
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704
The predictive effects of adiponectin and irisin hormones on diagnosis and clinical involvement of Sarcoidosis
Published 2024-12-01“…Adipokines and myokines secreted from adipose and muscle tissue play a role in the pathogenesis or protection against many inflammatory and autoimmune diseases in which inflammation and immunity form the basis. …”
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705
Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review
Published 2025-01-01“…Many diseases in livestock species such as mastitis, laminitis, neuromuscular disorders, autoimmune diseases, and some debilitating diseases are not covered completely by the existing drugs and treatment can be improved by using different types of stem cells like embryonic stem cells, adult stem cells, and induced pluripotent stem cells. …”
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706
Autoantibody to MDM2: A Potential Serological Marker of Systemic Lupus Erythematosus
Published 2015-01-01“…Systemic lupus erythematosus (SLE) is one of the systemic autoimmune diseases characterized by the polyclonal autoantibody production. …”
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707
Comprehensive Enteroviral Serology Links Infection and Anti‐Melanoma Differentiation‐Associated Protein 5 Dermatomyositis
Published 2025-01-01“…Objective Idiopathic inflammatory myopathies (IIMs) are a group of heterogeneous, systemic autoimmune diseases characterized by specific clinical features and, frequently, skeletal muscle inflammation. …”
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708
A minimal mathematical model for the initial molecular interactions of death receptor signalling
Published 2012-06-01“…TNF itself is a strong proinflammatory regulator of the innate immune system, but has been also recognized as a major factor in progression of autoimmune diseases. A subgroup of the TNF ligand family, including TNF, signals via so-called death receptors, capable to induce a major form of programmed cell death, called apoptosis. …”
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709
Progressive Intramuscular Haematoma in a 12-Year-Old Boy: A Case of Acquired Haemophilia A
Published 2018-01-01“…AHA is associated with several underlying pathologies such as pregnancy, autoimmune diseases, malignancy, medications and infections; however, up to 50% of reported cases are idiopathic. …”
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710
Prevalence of Anti-JC Virus (JCV) Antibodies in the Multiple Sclerosis (MS) Population in Cyprus: A Retrospective Study
Published 2019-01-01“…In recent years, a new subpopulation of patients at risk for PML has emerged, due to the growing use of immunomodulatory or immunosuppressive therapies in autoimmune diseases such as multiple sclerosis (MS). The anti-JCV antibody index is used as a stratification tool in assessing the risk of developing PML. …”
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711
MicroRNA Expression Profiling in Behçet’s Disease
Published 2018-01-01“…Differential expression of miRNAs has been reported in several inflammatory autoimmune diseases; however, their role in BD is not fully elucidated. …”
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712
Development and Characterisation of a Novel NF-κB Reporter Cell Line for Investigation of Neuroinflammation
Published 2017-01-01“…Aberrant activation of the transcription factor NF-κB, as well as uncontrolled inflammation, has been linked to autoimmune diseases, development and progression of cancer, and neurological disorders like Alzheimer’s disease. …”
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713
Mast cells: key players in digestive system tumors and their interactions with immune cells
Published 2025-01-01“…They play a significant role in protecting human health and in the pathophysiology of various illnesses, including allergies, cardiovascular diseases and autoimmune diseases. Recent studies in tumor-related research have demonstrated that mast cells exert a substantial influence on tumor cell behavior and the tumor microenvironment, exhibiting both pro- and anti-tumor effects. …”
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714
Progress of CCL20-CCR6 in the airways: a promising new therapeutic target
Published 2024-12-01“…According to current research, the CCL20-CCR6 has been established as acritical player in a diverse range of inflammatory, oncogenic, and autoimmune diseases. Within the respiratory system, CCL20-CCR6 demonstrates heightened expression in conditions such as allergic asthma, chronic airway inflammation, non-small cell lung cancer (NSCLC), chronic obstructive pulmonary disease (COPD), and other respiratory diseases, which is conducive to the inflammatory mediators recruitment and tumor microenvironment remodeling. …”
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715
Large-Scale Screening in General Population Children for Celiac Disease with a Multiplex Electrochemiluminescence (ECL) Assay
Published 2020-01-01“…It also provides a high efficient tool with its unique advantage of multiplexing measurements to screen for multiple autoimmune diseases simultaneously in general population.…”
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716
MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway
Published 2025-01-01“…In summary, this study reveals the diverse roles of MAPK4 in regulating of B cell functions, with potential implications for developing therapeutic strategies for RA and related autoimmune diseases.…”
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717
Anaemia of inflammation in sickle cell disease: A review of aetiopathogenesis, management, and prevention of sterile and septic inflammation in patients with sickle cell disease
Published 2025-01-01“…ASTERIN is driven by STERIN, which is relentless and occurs even in steady-state, and is often aggravated by crisis and/or autoimmune diseases. ASEPTIN is driven by SEPTIN, which occurs only during infections. …”
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718
Comparison of Vitamin D Levels in Patients with Chronic Lymphocytic Thyroiditis and the Normal Population, and Role of Vitamin D on Autoimmunity
Published 2022-08-01“…Purpose It is known that vitamin D deficiency has a role in the formation of autoimmune diseases, inflammatory bowel disease, rheumatoid arthritis, multiple sclerosis, diabetes, many types of cancer and heart diseases. …”
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719
ABIN1 Inhibits Inflammation through Necroptosis-Dependent Pathway in Ulcerative Colitis
Published 2022-01-01“…A recent study revealed that an ubiquitin binding protein ABIN1 played a role in tissue homeostasis and autoimmunity diseases which involved in the anti-inflammatory response of intestinal epithelia cells. …”
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720
An Immunological and Molecular Study of Regulatory T-cell Activity in Iraqi Patients with Psoriasis Treated by Topical and Biological Therapy
Published 2024-08-01“…Objective: Transforming growth factor-beta (TGF-β), an anti-inflammatory cytokine, plays a crucial role in restraining the proliferation and differentiation of T effector cells in autoimmune diseases. Glycoprotein A repetitions predominant (GARP), belonging to the leucine-rich repeat protein family, functions in facilitating the presentation of TGF-β on the surface of regulatory T-cells. …”
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