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341
Diagnosis and presenting features of autoimmune hepatitis at a central referral hospital in South Africa
Published 2024-04-01“…A diagnosis of a coexistent autoimmune disease was made in 22.5% of patients, with Systemic Lupus Erythematosus (SLE) being the most common (12.5%). …”
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342
Macrophage Activation Syndrome/Secondary Hemophagocytic Lymphohistiocytosis in Adult‐Onset Still's Disease: An Uncommon Initial Presentation in a Young Nepalese Female: A Case Repo...
Published 2025-01-01“…HLH may be due to immunosuppression, infections, cancer, or autoimmune diseases with fever and cytopenia. HLH which occurs in adult‐onset Stills disease (AOSD) is called secondary HLH, also known as macrophage activation syndrome (MAS). …”
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343
Bibliometric analysis of metformin as an immunomodulator (2013–2024)
Published 2025-01-01“…Recent research has highlighted metformin’s application in aging, autoimmune diseases, COVID-19, and tuberculosis. Additionally, its role in regulating inflammation and gut microbiota is also being investigated.ConclusionOverall, the immunomodulatory effects of metformin were investigated in anti-tumor, antiviral, anti-aging, and autoimmune disease research. …”
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344
Mixed Pulmonary Infection, Asthma, and Nephrotic Syndrome in a Patient Diagnosed with Selective IgA Deficiency: A Case Report
Published 2025-01-01“…Chenxi Yan, Junke Qiu, Xiaohong Pan, Xiaoqin Huang, Lei Pan, Caihong Wang, Minjie Mao Zhejiang Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Zhejiang, 310003, People’s Republic of ChinaCorrespondence: Minjie Mao, Zhejiang Provincial Hospital of Integrated Traditional Chinese and Western Medicine, 208 huancheng East Road, Gongshu District, Hangzhou, 310003, People’s Republic of China, Tel +86 15825500408, Email maominjie0909@163.comAbstract: Patients with selective IgA deficiency could have various clinical presentations ranging from asymptomatic to severe respiratory or gastrointestinal tract infection, as well as autoimmune disease and allergic reactions. Selective IgA deficiency is relatively common in Caucasians, but it is rare in the Asian population, meaning it could be easily missed in the clinic. …”
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345
Evaluation of Inflammation-Related Proteins in Multiple Sclerosis Disease with Relapses and Remissions
Published 2024-08-01“…Objective: Multiple sclerosis (MS) is an autoimmune disease affecting the brain and spinal cord by demyelination and neurodegeneration. …”
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346
Treatment of rheumatoid arthritis using dual-targeted and dual-response intelligent micelles: a “three birds with one stone” strategy
Published 2025-02-01“…Abstract Rheumatoid arthritis (RA) is an autoimmune disease whose pathophysiology is closely related to inflammation-associated cells and the microenvironment of inflamed joints. …”
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347
Assessment of XCI skewing and demonstration of XCI escape region based on single-cell RNA sequencing: comparison between female Grave’s disease and control
Published 2025-01-01“…Abstract Background The reactivation and loss of mosaicism hypothesis due to X chromosome inactivation (XCI) skewing and escape could influence gender differences in autoimmune diseases. XCI selectively inactivates one of the two X chromosomes in females. …”
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348
Confounding Risk Factors in Developing Type 1 Diabetes Mellitus among Children and Adolescents at Sulaimani Chronic Diabetes Health Center
Published 2021-07-01“…Residency and Family history of autoimmune disease were ranked in the fifth line of factor, finally the weakest factor is nationality by total variance of 8.552%. …”
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349
Evaluation of Clinical Interest of Anti-Aquaporin-4 Autoantibody Followup in Neuromyelitis Optica
Published 2013-01-01“…Neuromyelitis optica (NMO) is an autoimmune disease in which a specific biomarker named NMO-IgG and directed against aquaporin-4 (AQP4) has been found. …”
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350
The Role of PPAR Gamma in Systemic Sclerosis
Published 2015-01-01“…Fibrosis is recognized as an important feature of many chronic diseases, such as systemic sclerosis (SSc), an autoimmune disease of unknown etiology, characterized by immune dysregulation and vascular injury, followed by progressive fibrosis affecting the skin and multiple internal organs. …”
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351
Severe Renal Hemorrhage in a Pregnant Woman Complicated with Antiphospholipid Syndrome: A Case Report
Published 2011-01-01“…Antiphospholipid syndrome is a systemic autoimmune disease with thrombotic tendency. Consensus guidelines for pregnancy with antiphospholipid syndrome recommend low-dose aspirin combined with unfractionated or low-molecular-weight heparin because antiphospholipid syndrome causes habitual abortion. …”
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352
Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome
Published 2018-01-01“…No effective treatment for Sjögren’s syndrome (SS), a chronic autoimmune disease affecting mainly salivary and lacrimal glands, is available now. …”
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353
AMPD1 and MTHFR genes are not associated with calcium levels in rheumatoid arthritis patients with methotrexate therapy in Indonesia
Published 2025-01-01“…Abstract Rheumatoid Arthritis (RA) is a chronic and progressive autoimmune disease that affects synovial tissues has greater risk of developing secondary osteoporosis (OP). …”
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354
Immunoglobulin Gamma-Like Therapeutic Bispecific Antibody Formats for Tumor Therapy
Published 2019-01-01“…Bispecific antibodies (BsAbs) are a sort of dual functional proteins with specific binding to two distinct targets, which have become a focus of interest in antibody engineering and drug development research and have a promising future for wide applications in cancer immunotherapy and autoimmune disease. The key of clinical application and commercial-scale manufacturing of BsAbs is the amenability to assembly and purification of desired heterodimers. …”
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355
Protective Effect of CXCR3+CD4+CD25+Foxp3+ Regulatory T Cells in Renal Ischemia-Reperfusion Injury
Published 2015-01-01“…Regulatory T cells (Tregs) suppress excessive immune responses and are potential therapeutic targets in autoimmune disease and organ transplantation rejection. …”
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356
Altered Autophagy-Associated Genes Expression in T Cells of Oral Lichen Planus Correlated with Clinical Features
Published 2016-01-01“…Oral lichen planus (OLP) is a T cell-mediated inflammatory autoimmune disease. Autophagy has emerged as a fundamental trafficking event in mediating T cell response, which plays crucial roles in innate and adaptive immunity. …”
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357
Strengths of pelvic floor muscles in women with multiple sclerosis and its relationship with urinary incontinence and quality of life
Published 2025-01-01“…BackgroundMultiple sclerosis (MS) is a debilitating autoimmune disease that mostly affects women.ObjectivesIn this study we evaluated the relationship of pelvic muscle strengths with urinary incontinence and quality of life in women with MS.Materials and methodsIn this cross-sectional study 87 women with MS were recruited. …”
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358
Th1/Th17-Related Cytokines and Chemokines and Their Implications in the Pathogenesis of Pemphigus Vulgaris
Published 2017-01-01“…Pemphigus vulgaris (PV) is an autoimmune disease characterized by the presence of IgG autoantibodies against desmoglein-3. …”
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359
Cryptogenic Organizing Pneumonia with a Rare Radiographic Presentation of a Diffuse Micronodular Pattern Mimicking Miliary Lung Infiltration: A Case Report and Review of the Litera...
Published 2020-01-01“…His final culture results, microbiological data and serology workup for autoimmune disease were all unremarkable. The patient was diagnosed with COP and was started on systemic corticosteroids. …”
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