Osthole regulates N6‐methyladenosine‐modified TGM2 to inhibit the progression of rheumatoid arthritis and associated interstitial lung disease by Xian Lin, Jian Chen, Cheng Tao, Lianxiang Luo, Juan He, Qingwen Wang

“…Abstract Rheumatoid arthritis (RA) is an inflammatory autoimmune disease, and RA interstitial lung disease (ILD) is a severe complication of RA. …”
Get full text

Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation by Yi Shen, Changli Lu, Ruoting Men, Jianping Liu, Tinghong Ye, Li Yang

“…No significant difference was found in the gender, age, IAIHG score (pretreatment/posttreatment), definite diagnosis rate, extrahepatic autoimmune disease, onset time, or treatment before biopsy between the acute and chronic groups. …”
Get full text

Myasthenic Crisis in an Elderly Patient with Positive Antibodies against Acetylcholine and Anti-MuSK, Successfully Treated with Noninvasive Mechanical Ventilation by José A. Fernández, Antonio Fernández-Valiñas, Daniel Hernández, Joel Orozco, Antonio Lugo

“…Myasthenia gravis is an autoimmune disease characterized by muscle weakness. Subjects with antibodies against acetylcholine usually have greater ocular symptoms, lower bulbar weakness, and fewer respiratory complications, compared to individuals with anti-MuSK antibodies. …”
Get full text

A rare case of recurrent polychondritis with aortic valve involvement by N.V. Bortniak, O.A. Yepanchintseva, G.I. Kovtun, S.I. Dorofeieva, O.S. Chumak, G.M. Prus, O.J. Zharinov, B.M. Todurov

“…The article presents a clinical case of aortic valve disease and recurrent polychondritis (autoimmune disease) with lesions of cartilage tissue in 68-year-old patient admitted to a cardiac surgery clinic due to need for surgical treatment of aortic heart disease. …”
Get full text

A computational approach to drug design for multiple sclerosis via QSPR modeling, chemical graph theory, and multi-criteria decision analysis by Fozia Bashir Farooq, Nazeran Idrees, Esha Noor, Nouf Abdulrahman Alqahtani, Muhammad Imran

“…Abstract Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system with an unknown etiology. …”
Get full text

Th17 Cell Enhances CD8 T-Cell Cytotoxicity via IL-21 Production in Emphysema Mice by Min-Chao Duan, Ying Huang, Xiao-Ning Zhong, Hai-Juan Tang

“…Emphysema is a T-cell mediated autoimmune disease caused predominantly by cigarette smoking. …”
Get full text

The Association between Antiphospholipid and Coagulation in Pregnant Women with Blood Clotting by Dabah Dakil Awad, Iktefa Abdul Hameed Mohammed Saeed, Maha El. Jasim

“…Background: Antiphospholipid syndrome is a systemic hematological autoimmune disease characterized by a hypercoagulable state, which is associated with vascular thrombosis and/or obstetric morbidity characterized by miscarriage, fetal death, and/or premature birth. …”
Get full text

Clinical Outcomes in Patients with Cardiac Lupus: A Retrospective Study by K Maria Koshy, Tarun George, Sohini Das, J V Punitha, Sudha Jasmine Rajan, Bijesh Yadav, Thambu David Sudarsanam, Vijay Prakash Turaka

“…Objectives: Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect every organ system. The study aimed to analyze the clinical manifestations, laboratory findings, antibody associations, and clinical outcomes of patients with cardiac lupus. …”
Get full text

Abrogation of mercuric chloride-induced nephritis in the Brown Norway rat by treatment with antibodies against TNFα by A. Molina, F. Sánchez-Madrid, T. Bricio, A. Martín, E. Escudero, V. Alvarez, F. Mampaso

“…HgCl2 induces an autoimmune disease in the Brown Norway rat characterized by synthesis of autoantibodies (mainly, anti-GBM Abs), severe proteinuria and interstitial nephritis. …”
Get full text

Clinical and Capillaroscopic Modifications of the Psoriatic Plaque during Therapy: Observations with Oral Acitretin by Giuseppe Stinco, Cinzia Buligan, Enzo Errichetti, Francesca Valent, Pasquale Patrone

“…Psoriasis is considered to be an inflammatory autoimmune disease, where angiogenesis plays an undefined pathogenetic role. …”
Get full text

Association of disease activity with programmed cell death 1 and its ligand programmed cell death ligand 1 expressions in lupus patients by Eman Eissa, Rania Kandil, Nehal El-Ghobashy, Walaa Abdelfattah, Zainab Hammouda, Sara Medhat Gadelsayed, Faten Bayoumi

“…Background: Programmed cell death 1(PD-1)/programmed cell death ligand 1 (PD-L1) pathway is an immune checkpoint implicated in immune tolerance and involved in the pathogenesis of several autoimmune diseases. Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple immune dysregulation. …”
Get full text

New treatment options for generalized myasthenia gravis by Antanas Vaitkus, J. Čiauškaitė, M. Malakauskaitė, M. Baublytė

“…Myasthenia gravis is an autoimmune disease in which autoantibodies against the postsynaptic membrane proteins of the neuromuscular junction disrupt impulse transmission thus causing pathological muscle weakness and fatigue that worsens throughout the day. …”
Get full text

Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells by Nadine E. Rekittke, Meidjie Ang, Divya Rawat, Rahul Khatri, Thomas Linn

“…Type 1 diabetes is an autoimmune disease resulting in the permanent destruction of pancreatic islets. …”
Get full text

The Impact of T Cell Vaccination in Alleviating and Regulating Systemic Lupus Erythematosus Manifestation by Liuye Huang, Yuan Yang, Yu Kuang, Dapeng Wei, Wanyi Li, Qin Yin, Juan Pang, Zhongwei Zhang

“…Systemic lupus erythematosus (SLE) is an autoimmune disease identified by a plethora of production of autoantibodies. …”
Get full text

Manifestaciones bucales de la enfermedad celíaca en pacientes geriátricos consumidores de gluten by Gladys Aída Estrada Pereira, Jesús Díaz Fondén, Alina Márquez Chacón

“…<p><strong>Foundation</strong>: Celiac disease is a chronic inflammatory and autoimmune disease that affects genetically susceptible individuals due to a permanent intolerance to gluten. …”
Get full text

J-TAIL-2: A Prospective, Observational Study of Atezolizumab Combined With Carboplatin and Etoposide in Patients With Extensive-Stage SCLC in Japan by Eisaku Miyauchi, MD, PhD, Makoto Nishio, MD, PhD, Kadoaki Ohashi, MD, PhD, Atsushi Osoegawa, MD, PhD, Eiki Kikuchi, MD, PhD, Hideharu Kimura, MD, PhD, Yasushi Goto, MD, PhD, Junichi Shimizu, MD, PhD, Hiroshige Yoshioka, MD, PhD, Ichiro Yoshino, MD, PhD, Toshihiro Misumi, PhD, Nobuyuki Katakami, MD, PhD, Masahide Oki, MD, PhD, Takashi Kijima, MD, PhD, Kenichi Chikamori, MD, PhD, Kazumi Nishino, MD, PhD, Yuki Kobayashi, MS, Asako Miwa, BA, Misa Tanaka, MS, Akihiko Gemma, PhD

“…., Eastern Cooperative Oncology Group performance status 2 or more, interstitial lung disease, autoimmune disease) versus IMpower133-like groups. Results: Overall, 403 patients were included; the median age was 71 years, 16.6% (n = 67) had an Eastern Cooperative Oncology Group performance status 2 or more, 26.8% (n = 108) had brain metastasis, 6.9% (n = 28) had interstitial lung disease, 4.0% (n = 16) had autoimmune disease, and 72.7% (n = 293) were IMpower133-unlike. …”
Get full text

Isolation, Characterization, and Molecular Modeling of a Rheumatoid Factor from a Hepatitis C Virus Infected Patient with Sjögren’s Syndrome by Yu-Ching Lee, Keng-Chang Tsai, Sy-Jye Leu, Tuan-Jen Wang, Chia-Yu Liu, Yi-Yuan Yang

“…To study IgG RFs in patients with other autoimmune diseases, phage display antibody libraries from a hepatitis C virus infected patient with Sjögren’s syndrome were constructed. …”
Get full text

The Beneficial Effect of Human Amnion Mesenchymal Cells in Inhibition of Inflammation and Induction of Neuronal Repair in EAE Mice by Jun Shu, Xiaojuan He, Hong Li, Xue Liu, Xuemei Qiu, Tongliang Zhou, Ping Wang, Xiaojie Huang

“…Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system (CNS). …”
Get full text

Integrative genetics and multiomics analysis reveal mechanisms and therapeutic targets in vitiligo highlighting JAK STAT pathway regulation of CTSS by Zi-yue Dong, Ming-jie He, Yong-kai Yu, Fang Wang, Peng-yuan Zhao, De-long Ran, De-shuang Fu, Qing He, Run-ping Yang, Jiang-an Zhang

“…Abstract Vitiligo is a complex autoimmune disease characterized by the loss of melanocytes, leading to skin depigmentation. …”
Get full text

The Composition of Gut Microbiota in Patients Bearing Hashimoto’s Thyroiditis with Euthyroidism and Hypothyroidism by Simo Liu, Yaxin An, Bin Cao, Rongxin Sun, Jing Ke, Dong Zhao

“…Hashimoto’s thyroiditis (HT), a type of autoimmune disease, occurs due to genetic predisposition and environmental factors. …”
Get full text