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741
Pan-cancer analysis of CLDN1 and its functional study in gastric cancer
Published 2024-12-01“…Methods The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) databases were used to evaluate the expression patterns of CLDN1 in various cancer types and their association with clinical pathology, patient prognosis, and immune characteristics. …”
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742
What made people (more) positive toward the COVID-19 vaccine? Exploring positive and negative deviance perspectives
Published 2025-02-01“…The data were analyzed via semi-inductive coding with Atlas.ti.23. Results Positive deviants got vaccinated because they perceived COVID-19 as a threat, wanted to protect (vulnerable) others, or wanted to regain their freedom. …”
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743
Transcription factor FOXD1 and miRNA-204-5p play a major role in B4GALNT2 downregulation in colon cancer
Published 2025-01-01“…Through an in silico analysis of The Cancer Genome Atlas and of the Cancer Cell Line Encyclopedia, we identified the transcription factors FOXD1, FOXF2 and PGR as well as mir-204-5p as potential inhibitory agents. …”
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744
Simultaneous detection of eight cancer types using a multiplex droplet digital PCR assay
Published 2025-01-01“…Based on previous data analyses using The Cancer Genome Atlas (TCGA), we selected differentially methylated targets for eight frequent tumor types (lung, breast, colorectal, prostate, pancreatic, head and neck, liver, and esophageal cancer). …”
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745
Serum Cystatin S (CST4): A Novel Prognostic Marker for Gastric Cancer
Published 2025-01-01“…In addition, CST4 expression was correlated with immune cell infiltration using data from The Cancer Genome Atlas (TCGA). Patients were stratified by median CST4 levels, and Kaplan-Meier curves for OS and DFS were plotted. …”
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746
Development of a Ten-lncRNA Signature Prognostic Model for Breast Cancer Survival: A Study with the TCGA Database
Published 2020-01-01“…We downloaded RNA-seq data and relevant clinical information from the Cancer Genome Atlas (TCGA) database. Differentially expressed lncRNA were computed using the “edgeR” package and subjected to the univariate and multivariate Cox regression analysis. …”
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747
A Metabolic Gene Signature to Predict Overall Survival in Head and Neck Squamous Cell Carcinoma
Published 2020-01-01“…In this study, we used RNA sequencing (RNA-seq) data from the cancer genome atlas (TCGA), with validation in the GEO dataset to profile the metabolic microenvironment and define potential biomarkers for metabolic therapy. …”
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748
Classification of female MDD patients with and without suicidal ideation using resting-state functional magnetic resonance imaging and machine learning
Published 2025-01-01“…For our investigation, a brain atlas containing 116 regions of interest was used. …”
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749
Impact of rare non-coding variants on human diseases through alternative polyadenylation outliers
Published 2025-01-01“…Here we constructed a comprehensive atlas of alternative polyadenylation (APA) outliers (aOutliers), including 1334 3′ UTR and 200 intronic aOutliers, from 15,201 samples across 49 human tissues. …”
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750
Integrating bioinformatics and machine learning to identify AhR-related gene signatures for prognosis and tumor microenvironment modulation in melanoma
Published 2025-01-01“…However, the specific downstream targets and mechanisms by which AhR influences melanoma remain insufficiently understood.MethodsMelanoma samples from The Cancer Genome Atlas (TCGA) and normal skin tissues from the Genotype-Tissue Expression (GTEx) database were analyzed to identify differentially expressed genes, which were intersected with a curated list of AhR-related pathway genes. …”
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751
Pre-service teachers' perceptions of physical, socioemotional and cognitive traits in gifted students: unveiling bias?
Published 2025-01-01“…The study delves specifically into the physical characteristics attributed to gifted students through qualitative analysis addressing co-occurrence coefficients (Atlas.ti 9).ResultsThe results suggest that pre-service teachers described gifted students as more intelligent and with better physical attributes, especially gifted females. …”
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752
Identification of MYC and STAT3 for early diagnosis based on the long noncoding RNA-mRNA network and bioinformatics in colorectal cancer
Published 2025-01-01“…Quantitative Real-Time PCR (qRT-PCR) was performed to validate MYC and STAT3 expression levels, and findings were further confirmed using the Human Protein Atlas (HPA) database.ResultsDatabase analysis revealed significant differential expression of MYC and STAT3 between normal and CRC tissues. …”
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753
Integrating RNA-seq and scRNA-seq to explore the prognostic features and immune landscape of exosome-related genes in breast cancer metastasis
Published 2025-12-01“…Objective This study aims to explore the role of exosome-related genes in breast cancer (BRCA) metastasis by integrating RNA-seq and single-cell RNA-seq (scRNA-seq) data from BRCA samples and to develop a reliable prognostic model.Methods Initially, a comprehensive analysis was conducted on exosome-related genes from the BRCA cohort in The Cancer Genome Atlas (TCGA) database. Three prognostic genes (JUP, CAPZA1 and ARVCF) were identified through univariate Cox regression and Lasso-Cox regression analyses, and a metastasis-related risk score model was established based on these genes. …”
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754
Patient Perspectives on Personalized Risk Communication Using Polygenic Risk Scores to Inform Colorectal Cancer Screening Decisions
Published 2025-02-01“…Thematic analysis was conducted using Atlas.ti, Version 8. Results: Of the 19 participants who successfully completed polygenic risk score–related testing and a semistructured interview, 13 were female, 14 never smoked cigarettes, 6 were Hispanic, and 13 were non-Hispanic White. …”
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755
Aberrant DNA Methylation of FTH-1 and SHOX2 Contributes to Lung Cancer Progression
Published 2025-01-01“…Ferritin heavy chain 1 (FTH-1) and SHOX homeobox 2 (SHOX2) DNA methylation were investigated in non-small cell lung cancer (NSCLC) as novel epigenetic biomarkers.Method: In this case-control study, we initially evaluated the diagnostic value of FTH-1 and SHOX2 DNA methylation, and the Cancer Genome Atlas (TCGA) data on the methylation profile of NSCLC was analyzed. …”
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756
The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer
Published 2024-11-01“…In this study, the data originated from the Genotype-Tissue Expression (GTEx) and the Cancer Genome Atlas (TCGA) databases were input into multiple online bioinformatic tools to study the characteristics of NOTCH1 in pan-cancer. …”
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757
NIPAL1 as a prognostic biomarker associated with pancreatic adenocarcinoma progression and immune infiltration
Published 2025-01-01“…Primitive RNA sequencing (RNA-seq) data of PAAD from The Cancer Genome Atlas (TCGA) was utilized for bioinformatics analysis to characterize the expression levels of NIPAL1 in tumor and normal tissues. …”
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758
Genome wide identification of Dof transcription factors in Carmine radish reveals RsDof33 role in cadmium stress and anthocyanin biosynthesis
Published 2025-02-01“…Cd stress-induced RsDof expression patterns were studied using an RNA-seq atlas and qRT-PCR. The majority of RsDofs were tissue-specific and Cd-sensitive. …”
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759
The Use of Machine Learning to Create a Risk Score to Predict Survival in Patients with Hepatocellular Carcinoma: A TCGA Cohort Analysis
Published 2021-01-01“…Methods. The Cancer Genome Atlas (TCGA-LIHC) was analyzed for differentially expressed genes. …”
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760
¿Qué necesitan los centros y las familias para poder forjar una alianza? La perspectiva del profesorado de Educación Infantil y Primaria
Published 2025-01-01“…Se analizó su discurso mediante un análisis de contenido empleando el programa Atlas-ti. Resultados. Emergieron dos subdimensiones, una referida a las necesidades de los centros (cinco categorías) y otra a las de las familias (una categoría). …”
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