Atherogenic index of plasma and coronary artery disease: a systematic review and meta-analysis of observational studies by Ramin Assempoor, Mohammad Shahabaddin Daneshvar, Aryan Taghvaei, Alireza Sattari Abroy, Amir Azimi, John R. Nelson, Kaveh Hosseini

“…Abstract Background Atherogenic index of plasma (AIP), a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol concentrations, is associated with the burden of atherosclerosis. This study aimed to evaluate the relationship between AIP and coronary artery disease (CAD) risk, severity, and prognosis in populations with and without established CAD. …”
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Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans by Michela Palmieri, Spyridoula Maraka, Horace J. Spencer, Jeff D. Thostenson, Katherine Dishongh, Micheal Knox, Betty Ussery, Jesse Byrd, Jacqueline K. Kuipers, Sanaz Abedzadeh-Anaraki, Chitharanjan Duvoor, Yuanjie Mao, Lakshmi Menon, James S. Williams, Stavros C. Manolagas, Robert L. Jilka, Elena Ambrogini

“…Overexpression of anti-PC IgM ameliorates atherosclerosis and steatohepatitis, increases bone mass in young mice, and protects against high fat diet- and age-associated osteoporosis. …”
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Association of Diabetes Mellitus with Carotid Artery Stenosis Undergoing Coronary Artery Bypass Graft in Bangladesh: A Prospective Cross-Sectional Study by Chowdhury MAT, Joshi D, Magdum M, Adhikary D, Saklayen S, Alauddin M, Ranjan R, Adhikary AB

“…Md Abir Tazim Chowdhury,1 Dharmendra Joshi,2 Munama Magdum,3 Dipannita Adhikary,4 SMG Saklayen,5 Md Alauddin,6 Redoy Ranjan,4,6 Asit Baran Adhikary7 1Department of Cardiothoracic and Vascular Surgery, Evercare Hospital Dhaka, Dhaka, Bangladesh; 2Department of Cardiac Surgery, Shahid Gangalal National Heart Centre, Kathmandu, Nepal; 3Department of Preventive and Social Medicine, National Institute of Preventive and Social Medicine, Dhaka, Bangladesh; 4Department of Biological Sciences, Royal Holloway University of London, London, UK; 5Department of Vascular Surgery, Ibrahim Cardiac Hospital & Research Institute, Dhaka, Bangladesh; 6Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh; 7Department of Cardiac Surgery, Impulse Hospital, Dhaka, BangladeshCorrespondence: Md Abir Tazim Chowdhury, Department of Cardiothoracic and Vascular Surgery, Evercare Hospital Dhaka, Dhaka, Bangladesh, Tel +8801718123463, Email chowdhuryabir0@gmail.comBackground: Atherosclerosis is a systemic vascular disease commonly affecting coronary and carotid arteries, particularly in diabetes mellitus (DM). …”
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Association between COVID-19 severity and relatively high serum adiponectin levels at the time of admission by Ryohei Mineo, Shiro Fukuda, Shigehito Suzuki, Yoshito Ito, Sachiko Tamba, Takuya Sugiyama, Yuya Fujishima, Hitoshi Nishizawa, Iichiro Shimomura, Koji Yamamoto, Yuji Matsuzawa

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The prevention opportunities of retinopathy in diabetic patients – position paper endorsed by the Polish Lipid Association by Maciej Banach, Stanisław Surma, Grzegorz Dzida, Jacek Jóźwiak, Bogusław Okopień, Jacek Rysz, Konrad Szosland, Andrzej Grzybowski

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Characterization of Active Compounds of Different Garlic (Allium sativum L.) Cultivars by Szychowski Konrad A., Rybczyńska-Tkaczyk Kamila, Gaweł-Bęben Katarzyna, Świeca Michał, Karaś Monika, Jakubczyk Anna, Matysiak Magdalena, Binduga Urszula E., Gmiński Jan

“…Garlic (Allium sativum L.) has a reputation as a therapeutic agent for many different diseases such as microbial infections, hypertension, hypercholesterolaemia, diabetes, atherosclerosis and cancer. Health benefits of garlic depend on its content of biologically-active compounds, which differs between cultivars and geographical regions. …”
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Analysis of the mechanism of Zangjiangzhi capsule in the treatment of hyperlipidemia based on its ingredients identified by UHPLC-Q-Exactive-Orbitrap-MS by Changting He, Yuling Zhao, Yongchun Huang, Yudong Su, Shoude Zhang

“…Among these, the AGE-RAGE signaling pathway in diabetic complications, lipid and atherosclerosis pathways, regulation of lipids in adipocytes, and insulin resistance are related to HLP. …”
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Exploring similarities and differences in anti-atherosclerotic potential bioactives among Dendrobium species by UPLC-Q-Exactive Orbitrap MS by Yu Zhang, Xi Chen, Oushan Tang, Keyun Cheng, Lijun Ge, Weibo Lu, Jing Zheng, Yeshun Wu, Si-wei Wang, Xi-xi Zeng, Jing Xue, Yiwei Cui, Liting Ji, Qing Shen

“…Abstract Atherosclerosis is a primary cause of cardiovascular disease, straining healthcare systems. …”
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Short-term effects of follicle-stimulating hormone on immune function, lipid, and vitamin metabolism in transiently castrated men by Jéssica Guedes, Indira Pla, Aniel Sanchez, Gyorgy Marko-Varga, Gilberto Barbosa Domont, K Barbara Sahlin, Berk Hazir, Aleksander Giwercman, Fábio César Sousa Nogueira, Johan Malm, Yvonne Lundberg Giwercman

“…Background: Prostate cancer therapy with surgical or chemical castration with gonadotropin-releasing hormone (GnRH) agonists has been linked to elevated follicle-stimulating hormone (FSH) levels, which may contribute to secondary health disorders, including atherosclerosis and diabetes. Although recent findings suggest a role for FSH beyond the reproductive system, its metabolic impact remains unclear and difficult to disentangle from that of androgens. …”
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Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling by Xian Jin, Liang Liu, Yaping Zhang, Yin Xiang, Guizhi Yin, Yi Lu, Ludong Shi, Jian Dong, Chengxing Shen

“…Increased monocytes, particularly the inflammatory subset, are associated with accelerated atherosclerosis in diabetes through thus far incompletely defined mechanisms. …”
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Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease by Emmanouil Nychas, Andrea Marfil-Sánchez, Xiuqiang Chen, Mohammad Mirhakkak, Huating Li, Weiping Jia, Aimin Xu, Henrik Bjørn Nielsen, Max Nieuwdorp, Rohit Loomba, Yueqiong Ni, Gianni Panagiotou

“…Results Here, we collected public metagenomic data and integrated the taxonomy profiles with in silico generated community metabolic outputs, and detailed clinical data, of 1206 Chinese subjects w/wo metabolic diseases, including NAFLD (obese and lean), obesity, T2D, hypertension, and atherosclerosis. We identified highly specific microbiome signatures through building accurate machine learning models (accuracy = 0.845–0.917) for NAFLD with high portability (generalizable) and low prediction rate (specific) when applied to other metabolic diseases, as well as through a community approach involving differential co-abundance ecological networks. …”
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Mutual mediation effects of homocysteine and PCSK9 on coronary lesion severity in patients with acute coronary syndrome: interplay with inflammatory and lipid markers by Ping Jin, Juan Ma, Peng Wu, Yitong Bian, Xueping Ma, Shaobin Jia, Qiangsun Zheng

“…Abstract Background Homocysteine (Hcy) and the proprotein convertase subtilisin/kexin type 9 (PCSK9) significantly contribute to atherosclerosis (AS) as well as coronary lesion severity. …”
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Positive Associations between Adipocyte Fatty Acid-Binding Protein Level and Central Arterial Stiffness in Peritoneal Dialysis Patients by Cheng-Hao Sung, Bang-Gee Hsu, Jen-Pi Tasi, Chih-Hsien Wang, Chiu-Huang Kuo

“…Adipocyte fatty acid-binding protein (A-FABP) plays essential roles in lipolysis, insulin resistance, and atherosclerosis. This study aimed to evaluate the relationship between serum A-FABP levels and carotid-femoral pulse wave velocity (cfPWV) in peritoneal dialysis (PD) patients. …”
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Integrated electronic nose and multi-omics reveal changes in flavour characterization of cashmere goats and tan sheep meat by Ju Zhang, Shuang Pang, Ge Yan, Lulu Wang, Yuan Xu, Yuheng Bai, Ran Li, Xihong Wang, Yu Jiang

“…Specifically, TG(18:1/20:4/20:4), TG(18:1/18:2/20:4), TG(18:1/18:1/20:4), DG(18:0/20:4), and dodecanoic acid influence flavour by participating in key KEGG pathways such as the “fat digestion and absorption”, “cholesterol metabolism” and “lipid and atherosclerosis”. This study lays the groundwork for understanding the sources and mechanisms of mutton flavour compounds, providing valuable insights to support the growth and development of the mutton industry.…”
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CRISPR-Cas9 in Cardiovascular Medicine: Unlocking New Potential for Treatment by Klaudia Bonowicz, Dominika Jerka, Klaudia Piekarska, Janet Olagbaju, Laura Stapleton, Munirat Shobowale, Andrzej Bartosiński, Magdalena Łapot, Yidong Bai, Maciej Gagat

“…This article examines the potential of CRISPR-Cas9 in the treatment of various CVDs, including atherosclerosis, arrhythmias, cardiomyopathies, hypertension, and Duchenne muscular dystrophy (DMD). …”
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Clinical characteristics of patients with coronary artery disease by smoking status by Olga V. Nakhratova, Daria P. Tsygankova, Joseph M. Tsenter, Evgeny D. Bazdyrev

“…Percutaneous coronary interventions, history of acute cardiovascular events, arterial hypertension, multifocal atherosclerosis, and multivessel disease as defined by SYNTAX were more common in this group of patients. …”
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The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes by Zeki Dogan, Abdulhalim Senyigit, Sinem Durmus, Canan Duvarcı, Remise Gelişgen, Hafize Uzun, Omur Tabak

“…Abstract Affection of vascular structures is a known complication in diabetes and prediabetes. Subclinical atherosclerosis begins to develop years before both cardiovascular and cerebrovascular diseases become symptomatic. …”
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PPARG2 Pro12Ala and TNFα -308G>A Polymorphisms Are Not Associated with Heart Failure Development in Patients with Ischemic Heart Disease after Coronary Artery Bypass Grafting by Izabela Wojtkowska, Tomasz A. Bonda, Andrzej Tysarowski, Katarzyna Seliga, Janusz A. Siedlecki, Maria M. Winnicka, Janina Stępińska

“…TNFα and PPARγ are important modulators of metabolism, inflammation, and atherosclerosis. Coronary artery disease is the leading cause of heart failure (HF). …”
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Development and Validation of a Predictive Model Based on Serum Silent Information Regulator 6 Levels in Chinese Older Adult Patients: Cross-Sectional Descriptive Study by Yuzi You, Wei Liang, Yajie Zhao

“…ObjectivesThis study developed a nomogram to demonstrate the functionality of SIRT6 in assessing severity of coronary artery atherosclerosis. MethodsPatients aged 60 years and older with angina pectoris were screened for this single-center clinical study between October 1, 2022, and March 31, 2023. …”
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Evaluation of circadian rhythm and prognostic variability pre-and post-CEA or CAS treatment in patients with carotid artery stenosis by Yi Quan, Zhongzhu Wang, Tao Zhang, Yanyong Sui, Xin Zhang, Xueliang Ji, Ao-fei Liu, Weijian Jiang

“…ObjectiveCarotid artery stenosis, primarily caused by atherosclerosis, is a major risk factor for ischemic stroke. …”
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