Pentraxin 3 Is a Predictor for Fibrosis and Arterial Stiffness in Patients with Nonalcoholic Fatty Liver Disease by Kadir Ozturk, Omer Kurt, Tolga Dogan, Alptug Ozen, Hakan Demirci, Fatih Yesildal, Murat Kantarcioglu, Turker Turker, Ahmet Kerem Guler, Yıldırım Karslioglu, Battal Altun, Ahmet Uygun, Sait Bagci

“…To detect the presence of subclinical atherosclerosis in NAFLD, measurements of CIMT, FMD, and cf-PWV levels were performed. …”
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Nε-carboxyethyl-lysin influences atherosclerotic plaque stability through ZKSCAN3 acetylation-regulated macrophage autophagy via the RAGE/LKB1/AMPK1/SIRT1 pathway by Zhongwei Liu, Jing Liu, Xiqiang Wang, Yong Zhang, Yanpeng Ma, Gongchang Guan, Ya Yuwen, Ni He, Hanxiu Liu, Xingfeng Yu, Sen Ma, Junkui Wang, Jin Zhang, Ling Zhu, Yulian Zhang

“…Abstract Atherosclerosis, a chronic inflammatory condition characterized by plaque formation, often leads to instability, particularly under Type 2 diabetes mellitus (T2DM) conditions, which exacerbate cardiovascular risks. …”
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Metabolic Syndrome May Not be a Good Predictor of Coronary Artery Disease in the Iranian Population: Population-Specific Definitions are Required by Mahmoud Ebrahimi, Seyyed Mohammad Reza Kazemi-Bajestani, Majid Ghayour-Mobarhan, Mohsen Moohebati, Roghaye Paydar, Mohsen Azimi-Nezhad, Habib Ollah Esmaily, Gordon A. A. Ferns

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Influence of Helicobacter pylori Infection on Metabolic Syndrome in Old Chinese People by Wen Yang, Cunfu Xuan

“…H. pylori infection is one of the most common chronic infectious inflammatory diseases worldwide and is also a risk factor for atherosclerosis. Patients with metabolic syndrome are known to be at increased risk for atherosclerosis. …”
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Epidemiological and Pathogenic Relationship between Sleep Apnea and Ischemic Heart Disease by Carlos Carpio, Rodolfo Álvarez-Sala, Francisco García-Río

“…The pathophysiology of coronary artery disease in obstructive sleep apnea patients probably includes the activation of multiple mechanisms, as the sympathetic activity, endothelial dysfunction, atherosclerosis, and systemic hypertension. Moreover, chronic intermittent hypoxia and oxidative stress have an important role in the pathogenesis of coronary disease and are also fundamental to the development of atherosclerosis and other comorbidities present in coronary artery diseases such as lipid metabolic disorders. …”
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Low-Grade Systemic Inflammation Profile, Unrelated to Homocysteinemia, in Obese Children by Emanuel V. Economou, Ariadne V. Malamitsi-Puchner, Christos P. Pitsavos, Evangelia E. Kouskouni, Ioanna Magaziotou-Elefsinioti, George Creatsas

“…Thus, in POC, positively interrelated to each other, elevated CRP and unaltered SAA levels reveal a unique profile of the CLGSI, not explaining homocysteinemia-induced risk for future atherosclerosis.…”
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Exploring cardiovascular implications in systemic lupus erythematosus: A holistic analysis of complications, diagnostic criteria, and therapeutic modalities, encompassing pharmacol... by Dawi John, Affa Scarlet, Misakyan Yura, Fardeheb Sabrina, Kades Samuel, Kiriaki Anthony, Mohan Aishvaryaa Shree, Norris Brandon, Yoon Sonyeol, Venketaraman Vishwanath

“…Valvular diseases, atherosclerosis, and cardiac arrhythmias are prevalent, with immune complex deposition playing a role in atherosclerosis. …”
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CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway by Tianxin Geng, Yang Yan, Yue Zhang, Liangjie Xu, Guangyao Zang, Jin Chuan Yan

“…Endothelial dysfunction and apoptosis resulting from oxidative stress can lead to the development of atherosclerosis. Our group has previously showed that CD137 signaling contributes to the progression of atherosclerosis and the vulnerability of plaques. …”
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Unraveling the causal impact of smoking and its DNA methylation signatures on cardiovascular disease: Mendelian randomization and colocalization analysis by Si Cao, Youjie Zeng, Ke Pang, Minghua Chen, Ren Guo, Nayiyuan Wu, Chao Fang, Huiyin Deng, Xiaoyi Zhang, Xiaohui Xie, Wen Ouyang, Heng Yang

“…DNA methylation alteration at cg25313468 (located in the TSS1500 region of REST) is simultaneously associated with the risk of atrial fibrillation, coronary atherosclerosis, coronary heart disease, and myocardial infarction. …”
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COX-2 Gene Promoter Polymorphism and Coronary Artery Disease in Middle-Aged Men: The Helsinki Sudden Death Study by Kati H. Huuskonen, Tarja A. Kunnas, Minna M. Tanner, Jussi Mikkelsson, Erkki Ilveskoski, Pekka J. Karhunen, Seppo T. Nikkari

“…Cyclooxygenase (COX) catalyzes formation of prostaglandins that contribute to the inflammation in atherosclerosis. Our objective was to study whether the functional C variant of the −765G→C polymorphism in the human COX-2 gene associates with the severity of coronary atherosclerosis measured at the coronary artery level. …”
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The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications by O. Escribano, N. Beneit, C. Rubio-Longás, A. R. López-Pastor, A. Gómez-Hernández

“…This review discussed specifically the role of IR isoforms as well as IGF-IR in diabetes and its associated complications as obesity and atherosclerosis. Future research with new IR modulators might be considered as possible targets to improve the treatment of diabetes and its associated complications.…”
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Effect of Adiponectin Variant on Lipid Profile and Plasma Adiponectin Levels: A Multicenter Systematic Review and Meta-Analysis by Guiqing Wang, Yufeng Wang, Zhi Luo

“…Children with the rs266729 variant had a high risk to develop dyslipidemia, atherosclerosis, and even early onset of CAD in the future. …”
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Advancing Insights into Large-Artery Stiffening in Humans Through the Application of Multi-omics by Marie-Joe Dib

“…Importantly, LAS is pathologically different from atherosclerosis as it rather occurs primarily from changes in the medial aortic layer, and can manifest itself in the absence of plaque formation. …”
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Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1 by Yong Li, Qi Zhang, Na Li, Liting Ding, Jinping Yi, Yue Xiao, Shibiao Chen, Xuan Huang

“…Endothelial inflammation is a crucial event in the initiation of atherosclerosis. Here, we identify Ataxin-10 protein as a novel negative modulator of endothelial activation by suppressing IRF-1 transcription activity. …”
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Rituximab Efficacy during a Refractory Polyarteritis Nodosa Flare by Emmanuel Ribeiro, Thomas Cressend, Pierre Duffau, Marieke Grenouillet-Delacre, Marie Rouanet-Larivière, Anne Vital, Maïté Longy-Boursier, Patrick Mercié

“…Systemic vasculitis relapses are followed to accelerated atherosclerosis: severe ischemic lesions led to amputation of lower limbs. …”
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Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State by Marie Koren-Gluzer, Mira Rosenblat, Tony Hayek

“…Inflammatory processes are involved in atherosclerosis development. Macrophages play a major role in the early atherogenesis, and they are present in the atherosclerotic lesion in two phenotypes: proinflammatory (M1) or anti-inflammatory (M2). …”
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Imaging Collagen in Intact Viable Healthy and Atherosclerotic Arteries Using Fluorescently Labeled CNA35 and Two-Photon Laser Scanning Microscopy by Remco T.A. Megens, Mirjam G.A. oude Egbrink, Jack P.M. Cleutjens, Marijke J.E. Kuijpers, Paul H.M. Schiffers, Maarten Merkx, Dick W. Slaaf, Marc A.M.J. van Zandvoort

“…CNA35/OG488 is a good molecular imaging agent for atherosclerosis.…”
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Attenuation of Apoptosis by Telmisartan in Atherosclerotic Plaques of Apolipoprotein E Mice: Evaluation Using Technetium 99m–Annexin A5 by Yan Zhao, Songji Zhao, Yuji Kuge, H. William Strauss, Francis G. Blankenberg, Nagara Tamaki

“…Apoptosis imaging with 99m Tc–annexin A5 may be useful for evaluating the therapeutic effects of ARBs on atherosclerosis.…”
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Relation of Asymmetric Dimethylarginine Levels to Macrovascular Disease and Inflammation Markers in Type 2 Diabetic Patients by Mustafa Celik, Serkan Cerrah, Mahmut Arabul, Aysen Akalin

“…We recruited 50 type 2 diabetic patients with atherosclerosis, 50 type 2 diabetic patients without atherosclerosis, and 31 healthy control patients into our study. …”
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Impact of Diabetes on Cardiovascular Disease: An Update by Alessandra Saldanha de Mattos Matheus, Lucianne Righeti Monteiro Tannus, Roberta Arnoldi Cobas, Catia C. Sousa Palma, Carlos Antonio Negrato, Marilia de Brito Gomes

“…The proposed mechanisms that can link accelerated atherosclerosis and increased cardiovascular risk in this population are poorly understood. …”
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