The Morphological Features and Mitochondrial Oxidative Stress Mechanism of the Retinal Neurons Apoptosis in Early Diabetic Rats by Xiaoyan Li, Maonian Zhang, Huanfen Zhou

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Caspase-10 Is the Key Initiator Caspase Involved in Tributyltin-Mediated Apoptosis in Human Immune Cells by Harald F. Krug

“…As low as 200 nM up to 1 μM of TBT induces all signs of apoptosis in Jurkat T cells within 1 to 24 hrs of treatment. …”
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A Hypothesis Concerning a Potential Involvement of Ceramide in Apoptosis and Acantholysis Induced by Pemphigus Autoantibodies by Wendy B. Bollag

“…Our hypothesis is that: (1) the autoantibodies generate pathology through an alteration in ceramide metabolism in targeted keratinocytes, resulting in apoptosis and/or cell death and acantholysis, but only when the cell's ability to metabolize ceramide is exceeded, and (2) apoptosis in response to this altered ceramide metabolism is initiated and/or exacerbated by other agents that increase ceramide levels, such as cytokines, ultraviolet irradiation, and senescence.…”
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Effect of Exercise Preconditioning on Autophagy and Apoptosis of Cardiomyocytes in Aged Rats with Myocardial Ischemia Reperfusion Injury by LI Hongyu, YIN Xia, WANG Yanxia, Li Yuting, ZHU Luwen, TANG Qiang

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JNK Signaling Pathway Suppresses LPS-Mediated Apoptosis of HK-2 Cells by Upregulating NGAL by Mei Han, Yuxia Pan, Mengying Gao, Junli Zhang, Fan Wang

“…The JNK signaling pathway inhibits LPS-mediated apoptosis of renal tubular epithelial cells by upregulating NGAL.…”
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Proton pump inhibitors enhance chemosensitivity, promote apoptosis, and suppress migration of breast cancer cells by Ihraiz Worood G., Ahram Mamoun, Bardaweel Sanaa K.

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Inhibition of Growth and Induction of Apoptosis in Fibrosarcoma Cell Lines by Echinophora platyloba DC: In Vitro Analysis by Fatemeh Zare Shahneh, Samira Valiyari, Abbas Azadmehr, Reza Hajiaghaee, Saeid Yaripour, Ali Bandehagh, Behzad Baradaran

“…Cell death ELISA was employed to quantify the nucleosome production result from nuclear DNA fragmentation during apoptosis and determine whether the mechanism involves induction of apoptosis or necrosis. …”
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Vernolactone Promotes Apoptosis and Autophagy in Human Teratocarcinomal (NTERA-2) Cancer Stem-Like Cells by Nuwanka K. Abeysinghe, Ira Thabrew, Sameera R. Samarakoon, Meran K. Ediriweera, Kamani H. Tennekoon, Varuni P. C. Pathiranage, Anuka S. Mendis

“…Effects of vernolactone on apoptosis were investigated by phase contrast light microscopic and fluorescence microscopic analysis, caspase 3/7 expression, and real-time PCR of apoptosis-associated genes p53 and Survivin. …”
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The Blockade of IL6 Counterparts the Osmolar Stress-Induced Apoptosis in Human Conjunctival Epithelial Cells by Hee-Jung Ju, Yong-Soo Byun, Jee-Won Mok, Choun-Ki Joo

“…The concentration of IL6 showed time-dependent increase in cells treated with 500 mOsm. Although apoptosis of WKD cell is increased in treated 500 mOsm for 24 h, apoptosis reduced in WKD cell treated 500 mOsm with anti-IL6 for 24 h. …”
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Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats by Awyed Batah Almutairi, Abdulaziz Arif A. Alshammari, Arshad Husain Rahmani, Ali Yousif Babiker, Long Chiau Ming, Maha A. Aldubayan, Ahmad H. Alhowail, Vasudevan Mani

“…Post-experiment, brain tissues were analyzed for apoptosis, neuroinflammation, and oxidative stress markers to assess potential neurotoxicity. …”
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Polymorphic variants of the genes for enzymes of the antioxidant system, apoptosis and inflammation as potential predictors of myocardial infarction by T. R. Nasibullin, V. V. Erdman, Y. R. Timasheva, I. A. Tuktarova, A. A. Petinseva, G. F. Korytina

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The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells by Lu Lu, Ying Zhang, Wei Shi, Qian Zhou, Zhuoqi Lai, Yuepu Pu, Lihong Yin

“…Furthermore, copper induced apoptosis, characterized by increased expressions of Bcl2 X protein (Bax), caspase 3, and Poly (ADP-ribose) polymerase (PARP) and decreased expression of B-cell lymphoma 2 (Bcl2). …”
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Photodynamic Therapy with the Silicon Phthalocyanine Pc 4 Induces Apoptosis in Mycosis Fungoides and Sezary Syndrome by Minh Lam, YooJin Lee, Min Deng, Andrew H. Hsia, Kelly A. Morrissey, Chunlin Yan, Kashif Azzizudin, Nancy L. Oleinick, Thomas S. McCormick, Kevin D. Cooper, Elma D. Baron

“…Our data suggest that Pc 4-PDT preferentially induces apoptosis of CD4+CD7− malignant T-lymphocytes in the blood relative to CD11b+ monocytes and nonmalignant T-cells. …”
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The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis. by Patrick A Carroll, Brian W Freie, Pei Feng Cheng, Sivakanthan Kasinathan, Haiwei Gu, Theresa Hedrich, James A Dowdle, Vivek Venkataramani, Vijay Ramani, Xiaoying Wu, Daniel Raftery, Jay Shendure, Donald E Ayer, Charles H Muller, Robert N Eisenman

“…Loss of Mlx results in altered metabolism as well as activation of multiple stress pathways and GC apoptosis in the testes. This is concomitant with dysregulation of the expression of male-specific GC transcripts and proteins. …”
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Associations of NF-kappaB and Bax with Apoptosis in Varicose Veins of Women of Different Age Groups by Helle Evi Simovart, Andres Arend, Jüri Lieberg, Marina Aunapuu

“…The study revealed that in varicose veins ECs and SMCs apoptosis increased with advancing age. If increase in apoptosis during earlier stages of varicosities is probably regulated by intrinsic pathway, then in older patients other signaling pathways may be involved.…”
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Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition by Jasoda Choudhari, Snehal K. Nimal, Shridhar Chougule, Trupti Shinde, N.R. Dhatrak, Gopal C. Kundu, Rajesh N. Gacche

“…Mechanistic study of PJLME-AF was explored using ROS generation assay, apoptosis assays (Annexin V) assay, western blot (apoptotic protein, EMT markers, stem cell markers and signalling pathways), qPCR. …”
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Effects of Duhuo Jisheng Decoction on Calcium Homeostasis and Apoptosis of Chondrocytes under Endoplasmic Reticulum Stress by Qing LIN, Wenyi WANG, Danhong PAN, Yanfeng HUANG, Changlong FU, Jinxia YE

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Effects of annexin A1 on apoptosis and cell cycle arrest in human leukemic cell lines by Sabran Affidah, Kumolosasi Endang, Jantan Ibrahim

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Dynamic Expression of HDAC3 in db/db Mouse RGCs and Its Relationship with Apoptosis and Autophagy by Yuhong Fu, Ying Wang, Xinyuan Gao, Huiyao Li, Yue Yuan

“…Our results suggest the HDAC3 expression has a positive correlation with apoptosis and autophagy.…”
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Correction: Yinzhihuang injection induces apoptosis and suppresses tumor growth in acute myeloid leukemia cells

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