The anticancer properties, cell-cycle cytotoxicity and apoptosis of cissus rotundifolia, trema orientalis, and buddleja polystachya with ocular applications by Ali Hendi Alghamdi, Aimun A.E. Ahmed, Mahadi bashir, Haidar abdalgadir, Asaad khalid, Ashraf N. Abdalla, Mohamed E. elzubier, Riyad almaimani, Bassem refaat, Khalid alzahrani, Saleh MS. alghamdi, Sheraz gul

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The PPARδ Ligand GW501516 Reduces Growth but Not Apoptosis in Mouse Inner Medullary Collecting Duct Cells by Jordan Clark, Rania Nasrallah, Richard L. Hébert

“…These results show that a PPARδ ligand inhibits growth but does not affect anisomycin-apoptosis in a mouse IMCD cell line. This could have therapeutic implications for renal diseases associated with increased CD growth responses.…”
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Corrigendum to “Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis” by Yunan Gao, Hongxiao Yang, Yanbin Fan, Lin Li, Jiahui Fang, Wei Yang

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MLLT11 siRNA Inhibits the Migration and Promotes the Apoptosis of MDA-MB-231 Breast Cancer Cells by Xiangrong Liu, Wenqi Bai, Jianrong Li, Jinfeng Ma, Yan Liu, Zhixiang Wang, Linjie Hu, Zheng Li, Dimitri Papukashvili, Nino Rcheulishvili, Fusheng Wang, Xiaoqing Lu

“…Moreover, cell migration and invasion, as well as the protein levels of phosphatidylinositol 3-kinase (PI3K), AKT, matrix metalloproteinase (MMP) 2, and MMP9, were significantly lower in the groups treated with siRNA while the apoptosis was augmented. Collectively, MLLT11 siRNA elicited ameliorative properties on breast cancer cells, possibly via the inhibition of the PI3K/AKT signaling pathway.…”
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Inhibition of Murine Pulmonary Microvascular Endothelial Cell Apoptosis Promotes Recovery of Barrier Function under Septic Conditions by Lefeng Wang, Sanjay Mehta, Michael Brock, Sean E. Gill

“…Our recent work identified a strong correlation between PMVEC apoptosis and microvascular leak in septic mice in vivo, but the specific role of apoptosis in septic PMVEC barrier dysfunction remains unclear. …”
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ClC-3 Expression and Its Association with Hyperglycemia Induced HT22 Hippocampal Neuronal Cell Apoptosis by Feiyan Fan, Tao Liu, Xin Wang, Dongni Ren, Hui Liu, Pengxing Zhang, Zhen Wang, Nan Liu, Qian Li, Yanyang Tu, Jianfang Fu

“…Although apoptosis plays an important role in the development of Diabetic Encephalopathy (DE), the underlying molecular mechanisms remain unclear. …”
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MAC30 Knockdown Inhibits Proliferation and Enhance Apoptosis of Gastric Cancer by Suppressing Wnt/β-Cateninsignaling Pathway by Xiaohong Wu, Yong Zhang, Junping Guo, Xun Yan, Li Shen, Jianping Zhou, Jun Zhao, Min Zhuang, Zhihong Cao

“…However, the promotion of apoptosis by mitochondrial pathway was mediated by Bax/Bcl-2 upregulation. …”
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Effect of Electroacupuncture on Chondrocyte Apoptosis in Knee Osteoarthritis Rat Based on PI3K/Akt Signaling Pathway by Yuanyuan ZHANG, Xinyu JIANG, Xihai LI, Mingxia WU

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miR-504 Promoted Gastric Cancer Cell Proliferation and Inhibited Cell Apoptosis by Targeting RBM4 by Yi Zhang, Hongmei Yong, Jing Fu, Guangyi Gao, Huichang Shi, Xueyi Zhou, Mingsheng Fu

“…Cell proliferation and cell apoptosis were assessed by colony formation assay and flow cytometry, respectively. …”
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Protective Effect of Schisandrin on CORT-Induced PC12 Depression Cell Model by Inhibiting Cell Apoptosis In Vitro by Liu Yang, Yeqiu Wang, Lifeng An, Xinya Zhang, Jing Wang, Yi Wang, Ruyang Cheng, Chenxiang Li, Wei Ma

“…The LDH activity in each group of cells was detected by lactate dehydrogenase (LDH) kit. Apoptosis rate of each group was detected by Annexin V-FITC apoptosis assay kit. …”
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Anticancer Drug-Induced Apoptosis and Cytotoxicity in Prostate Cancer Cells Are Modulated by Organ-Specific Stromal Cell Factors by Bal L. Lokeshwar, Kamalaveni R. Prabhakar, Tie Yan Shang, Zafiria Mourelatos, De-Quan Li

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HA14-1 is Able to Reconstitute the Impaired Mitochondrial Pathway of Apoptosis in Renal Cell Carcinoma Cell Lines by Sebastian Heikaus, Linda van den Berg, Tobias Kempf, Csaba Mahotka, Helmut Erich Gabbert, Uwe Ramp

“…Renal cell carcinomas (RCCs) exhibit a marked resistance towards apoptosis. Although most apoptotic stimuli converge at the level of the mitochondria, little is known about the mitochondrial apoptosis pathway in renal cell carcinomas. …”
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RORγt inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apoptosis by Mia Collins, Rikard Pehrson, Hanna Grindebacke, Agnes Leffler, Marie Ramnegård, Helena Rannikmäe, Nina Krutrök, Linda Yrlid, Charlotte Pollard, Ian Dainty, Frank Narjes, Stefan von Berg, Antonio Llinas, Anna Malmberg, Jane McPheat, Eva Hansson, Elisabeth Bäck, Jenny Bernström, Thomas G. Hansson, David Keeling, Johan Jirholt

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MAGEB2-Mediated Degradation of EGR1 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cell Lines by Xueheng Zhao, Zenghui Huang, Yongzhe Chen, Qianyin Zhou, Fang Zhu, Huan Zhang, Dai Zhou

“…Our results offer new insights into the functional and regulatory mechanisms in MAGEB2-mediated human SSC line proliferation and apoptosis.…”
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Deoxycholic Acid Could Induce Apoptosis and Trigger Gastric Carcinogenesis on Gastric Epithelial Cells by Quantitative Proteomic Analysis by Yanyan Shi, Ying Wei, Ting Zhang, Jing Zhang, Ye Wang, Shigang Ding

“…Changes in the profiles of the differently expressed proteins were analyzed using the DAVID and STRING programs. Results. We found apoptosis was significantly induced in GES-1 cells by deoxycholic acid. …”
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Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

Subjects: “…apoptosis…”
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Apoptosis in the liver of male <em>db/db</em> mice during the development of obesity and type 2 diabetes by S. V. Michurina, I. Yu. Ishchenko, S. A. Arkhipov, M. A. Cherepanova, D. V. Vasendin, E. L. Zavjalov

“…The aim of this research was to study the expression of molecular cell regulators of apoptosis in liver cells of db/db mice males at different stages of obesity and diabetes development (at the age of 10 and 18 weeks). …”
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Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin by Wen-Tsan Chang, Hsiao-Ling Cheng, Bau-Shan Hsieh, Chien-Chih Chiu, King-Teh Lee, Kee-Lung Chang

“…Cotreatment with progesterone enhanced epirubicin-induced apoptosis, as evidenced by greater increase in caspase-3 activity and in the ratio of the apoptosis-regulating protein, Bax/Bcl-XL. …”
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The Impact of Advanced Glycation End-Products (AGEs) on Proliferation and Apoptosis of Primary Stem Cells: A Systematic Review by Lize Evens, Hanne Beliën, Dorien Deluyker, Annelies Bronckaers, Pascal Gervois, Marc Hendrikx, Virginie Bito

“…Whether AGEs have an impact on stem cell viability in regenerative medicine remains unclear, and research on the effect of AGEs on stem cell proliferation and apoptosis is still ongoing. Therefore, this systematic review provides a clear overview of the effects of glycated proteins on cell viability in various types of primary isolated stem cells used in regenerative medicine.…”
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Porphyra-334, a mycosporine-like amino acid, attenuates UV-induced apoptosis in HaCaT cells by Suh Sung-Suk, Oh Se Kyung, Lee Sung Gu, Kim Il-Chan, Kim Sanghee

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