Clinical utility of hematological parameters in aplastic anemia by Lizhong Zhang, Xiaonan Han, Qiujuan Zhu, Yu Qin, Yanan Jia

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Aplastic Anemia Treated with Eltrombopag during Pregnancy by Yuri Suminaga, Yoshitsugu Chigusa, Tadakazu Kondo, Haruko Okamoto, Yosuke Kawamura, Mana Taki, Masaki Mandai, Haruta Mogami

“…In patients with aplastic anemia, pancytopenia sometimes worsens during pregnancy, and relapse of aplastic anemia in pregnancy is common. …”
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A germline FLT3 variant in aplastic anemia by Lemchukwu C. Amaeshi, Amalia A. Sofianidi, Aditi Shastri, Mendel Goldfinger, Marina Konopleva, Amit K. Verma, Mark Chaitowitz, Ioannis Mantzaris

Subjects: “…Aplastic anemia…”
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Intraperitoneal Injection of Multiplacentas Pooled Cells Treatment on a Mouse Model with Aplastic Anemia by Jun Li, Hong Chen, Yan-Bo Lv, Qiang Wang, Zheng-Jun Xie, Li-Hua Ma, Jie He, Wei Xue, Shan Yu, Jun Guo, Ting-Hua Wang, Tian-Xi Wu, Xing-Hua Pan

“…Intraperitoneally transplanted multiplacentas pooled cells can survive and engraft into a host body through blood circulation, which can increase the life span of an aplastic anemia model mice, and delay but not abrogate the development of aplastic anemia. …”
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Aplastic anemia in a patient with papillary thyroid carcinoma complicated with Hashimoto’s thyroiditis: a case report by Fei Wu, Yiwei Xiao, Rui Hai, Xiaodong Chen, Shanshan Liu, Xiangyu Zhou

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Extra-Axial Hematoma and Trimethoprim-Sulfamethoxazole Induced Aplastic Anemia: The Role of Hematological Diseases in Subdural and Epidural Hemorrhage by Richard P. Menger, Rimal H. Dossani, Jai Deep Thakur, Frank Farokhi, Kevin Morrow, Bharat Guthikonda

“…To illustrate the development of spontaneous subdural hematoma secondary to aplastic anemia resulting from the administration of trimethoprim-sulfamethoxazole. …”
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Altered Expression of Hematopoiesis Regulatory Molecules in Lipopolysaccharide-Induced Bone Marrow Mesenchymal Stem Cells of Patients with Aplastic Anemia by Chandra Prakash Chaturvedi, Naresh Kumar Tripathy, Ekta Minocha, Akhilesh Sharma, Khaliqur Rahman, Soniya Nityanand

“…., macrophage inflammatory protein (MIP)-1α, tumor necrosis factor (TNF)-α, granulocyte colony-stimulating factor (G-CSF), stromal cell-derived factor (SDF)-1α, stem cell factor (SCF), and transforming growth factor (TGF)-β in lipopolysaccharide-induced bone marrow mesenchymal stem cells (BM-MSCs) and levels of their soluble forms in the culture supernatants of BM-MSCs and BM plasma of patients with acquired aplastic anemia (AA) (n=29) and controls (n=29). The BM-MSCs of AA patients as compared to controls had markedly lower expression of MIP-1α transcripts (p<0.001), higher expression of TNF-α (p<0.001), G-CSF (p<0.001), and SDF-1α (p<0.01) transcripts, and no difference in the expression of SCF and TGF-β transcripts. …”
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Dynamics of Graft Function Measured by DNA-Technology in a Patient with Severe Aplastic Anemia and Repeated Stem Cell Transplantation by Anna Karastaneva, Christian Urban, Herwig Lackner, Wolfgang Schwinger

“…Although bone marrow transplantation (BMT) from an HLA identical sibling is considered as treatment of choice in pediatric patients with severe aplastic anemia (SAA), a significant number of them experience graft failure (GF) after BMT. …”
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Genetic Associations in Acquired Immune-Mediated Bone Marrow Failure Syndromes: Insights in Aplastic Anemia and Chronic Idiopathic Neutropenia by Irene Mavroudi, Helen A. Papadaki

“…However, in immune-mediated bone marrow failure syndromes, such as acquired aplastic anemia and chronic idiopathic neutropenia, in which the pathophysiology results from a myelosuppressive bone marrow microenvironment mainly due to the presence of activated T lymphocytes, leading to the accelerated apoptotic death of the hematopoietic stem and progenitor cells, such genetic associations have been very limited. …”
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Expression of Shelterin Component POT1 Is Associated with Decreased Telomere Length and Immunity Condition in Humans with Severe Aplastic Anemia by Ting Wang, Shu-chong Mei, Rong Fu, Hua-quan Wang, Zong-hong Shao

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Fatal Epstein-Barr Virus Reactivation in an Acquired Aplastic Anemia Patient Treated with Rabbit Antithymocyte Globulin and Cyclosporine A by Tohru Takahashi, Yumiko Maruyama, Mayuko Saitoh, Hideto Itoh, Mitsuru Yoshimoto, Masayuki Tsujisaki

“…Epstein-Barr virus (EBV) associated lymphoproliferative disorder (LPD) after immunosuppressive therapy for aplastic anemia (AA) is extremely rare in a nontransplant setting and has not been well described. …”
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Severe Aplastic Anemia following Acute Hepatitis from Toxic Liver Injury: Literature Review and Case Report of a Successful Outcome by Kamran Qureshi, Usman Sarwar, Hicham Khallafi

“…Hepatitis associated aplastic anemia (HAAA) is a rare syndrome in which severe aplastic anemia (SAA) complicates the recovery of acute hepatitis (AH). …”
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Differential diagnosis of iron deficiency anemia from aplastic anemia using machine learning and explainable Artificial Intelligence utilizing blood attributes by B. S. Dhruva Darshan, Niranjana Sampathila, G. Muralidhar Bairy, Srikanth Prabhu, Sushma Belurkar, Krishnaraj Chadaga, S. Nandish

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Protective Effects of Chronic Intermittent Hypobaric Hypoxia Pretreatment against Aplastic Anemia through Improving the Adhesiveness and Stress of Mesenchymal Stem Cells in Rats by Jing Yang, Li Zhang, Handong Wang, Zan Guo, Yixian Liu, Yi Zhang, Chuan Wang, Quanhai Li

“…Aplastic anemia (AA) is a common malignant blood disease, and chronic intermittent hypobaric hypoxia (CIHH) has a beneficial effect against different diseases. …”
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Risk factors and clinical outcomes of cytomegalovirus infection following haploidentical hematopoietic stem cell transplantation in patients with aplastic anemia: a single-center retrospective study by Jia Feng, Jia Feng, Xinhe Zhang, Xinhe Zhang, Zhengwei Tan, Zhengwei Tan, Yuechao Zhao, Huijin Hu, Junfa Chen, Liqiang Wu, Qinghong Yu, Dijiong Wu, Baodong Ye, Wenbin Liu

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Current status and perspectives of hematopoietic cell transplantation in patients with paroxysmal nocturnal hemoglobinuria by Marek Ussowicz, Dawid Przystupski, Patrycja Mensah-Glanowska, Agnieszka Piekarska

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Fludarabine/Cyclophosphamide Conditioning Regimen in Aplastic Anemia Patients Receiving Matched-Sibling Donor Transplant Is Non-inferior to ATG/Cyclophosphamide: A Single-Center Experience from Pakistan by Uzma Zaidi, Mushkbar Fatima, Shafaq Abdul Samad, Kashif Shafique, Hira Fatima Waseem, Tasneem Farzana, Tahir Sultan Shamsi

“…The successful outcome of allogeneic hematopoietic stem cell transplant (HSCT) in aplastic anemia patients is driven by suitable donor selection, appropriate conditioning regimen, early intervention, and optimal supportive care after transplant. …”
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Acquired Amegakaryocytic Thrombocytopenia and Pure Red Cell Aplasia in Thymoma by Sumit Dahal, Eliza Sharma, Suyash Dahal, Binav Shrestha, Bikash Bhattarai

“…Association of thymoma with myasthenia gravis, pure red cell aplasia, and aplastic anemia is well documented. However, thymoma complicated by acquired amegakaryocytic thrombocytopenia (AAMT) is rarely reported. …”
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CLINICAL SIGNS AND TREATMENT OF NEW-ONSET BONE MARROW FAILURE ASSOCIATED SARS-COV-2 INFECTION IN CHILDREN : A SINGLE INSTITUTION PROSPECTIVE COHORT STUD by Mervat A M youssef, Ebtisam Shawky hmed, Dalia Tarik Kamal, khalid Elsayh, Mai A Abdelfatta, Hyam Hassan Mahran Mahran, Mostafa M Embaby

“…The objectives of this study were to identify the frequency and severity of aplastic anemia in Severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2) infected children as well as recognition of the response to treatment Methodology: 13 children with newly-diagnosed severe aplastic anemia enrolled in this prospective clinical trial. …”
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Cobalamin and Folic Acid Status in Relation to the Etiopathogenesis of Pancytopenia in Adults at a Tertiary Care Centre in North India by M. Premkumar, N. Gupta, T. Singh, T. Velpandian

“…Megaloblastic anemia 60.7%, aplastic anemia (7.8%), and leukemia (9.2%) were common causes. …”
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