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  1. 161

    Efficacy of vaccines based on chimeric or multiepitope antigens for protection against visceral leishmaniasis: A systematic review. by Karine Ferreira Lopes, Mariana Lourenço Freire, Silvane Maria Fonseca Murta, Edward Oliveira

    Published 2024-12-01
    “…Vaccines based on chimeric or multiepitope antigens hold significant potential to induce a highly effective and long-lasting immune response against infections by these parasites. …”
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    Combination of Culture, Antigen and Toxin Detection, and Cytotoxin Neutralization Assay for Optimal Clostridium difficile Diagnostic Testing by Michelle J Alfa, Shadi Sepehri

    Published 2013-01-01
    “…A C difficile diagnostic algorithm is necessary because diagnostic kits, mostly for the detection of toxins A and B or glutamate dehydrogenase (GDH) antigen, are not sufficient as stand-alone assays for optimal diagnosis of C difficile infection. …”
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    Immunological Responses and Epitope Mapping by Tuberculosis-Associated Antigens within the RD1 Region in Japanese Patients by Hideaki Nagai, Maho Suzukawa, Yumi Sakakibara, Ken Ohta, Pedro A. Reche, Koichi Suzuki, Yoshihiko Hoshino

    Published 2014-01-01
    “…Results of the ELISPOT assay led to the discovery of specific epitopes within the early secreted antigenic target 6 kDa (ESAT-6) and culture filtrate protein 10 kDa (CFP-10) proteins. …”
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    The Effect of PT Link and Waterbath Antigenic Retrieval Procedures On The Expression of Common Receptors In Breast Cancer Cases by Ahmed Abdelbadie, Elsadig Ahmed Adam, Manar Abdelrahman

    Published 2017-05-01
    “…Background: Antigen retrieval (AR) techniques play a major role in determining the quality and functional state of tissue proteins recovered from formalin fixed paraffin embedded blocks (FFPEB). …”
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  9. 169

    Evaluation of Humoral Immunity to Mycobacterium tuberculosis-Specific Antigens for Correlation with Clinical Status and Effective Vaccine Development by Mamiko Niki, Maho Suzukawa, Shunsuke Akashi, Hideaki Nagai, Ken Ohta, Manabu Inoue, Makoto Niki, Yukihiro Kaneko, Kozo Morimoto, Atsuyuki Kurashima, Seigo Kitada, Sohkichi Matsumoto, Koichi Suzuki, Yoshihiko Hoshino

    Published 2015-01-01
    “…However, the recent failure of a clinical trial for a booster BCG vaccine and increasing evidence of antibody-mediated immunity prompted us to evaluate humoral immunity to Mtb-specific antigens. Using Enzyme-Linked ImmunoSpot and Enzyme-Linked ImmunoSorbent Assays, we observed less correlation of both CMI and IgG titers with patient clinical status, including serum concentration of C reactive protein. …”
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  10. 170

    Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells by A. Jiménez-Periáñez, B. Abos Gracia, J. López Relaño, C. M. Diez-Rivero, P. A. Reche, E. Martínez-Naves, E. Matveyeva, M. Gómez del Moral

    Published 2013-01-01
    “…We show for the first time that MSMPs vehiculation of antigenic peptides enhances their MHC class I presentation by human MDDCs to CD8 T lymphocytes.…”
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  11. 171

    The modulating effect of circulating carbohydrate antigen 125 on ST2 and long-term recurrent morbidity burden by Elena Revuelta-López, Rafael de la Espriella, Gema Miñana, Enrique Santas, Sandra Villar, Juan Sanchis, Antoni Bayés-Genís, Julio Núñez

    Published 2025-01-01
    “…Emerging evidence suggests that carbohydrate antigen 125 (CA125) may act as a ligand that modulates the inflammatory response. …”
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    Study of protectivity and antigenicity of vaccine based on ' cultural Asia-1 No.2145/ Tajikistan/2011 FMD Virus by D. A. Lozovoy, V. A. Starikov, D. V. Mikhalishin

    Published 2018-04-01
    “…The paper presents the results of tests aimed to study the protective antigen differences between Asia-1 No. 2145/Tajikistan/2011 isolate and Asia-1 Shamir 3/89 FMD cultural virus vaccine strain.…”
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  16. 176

    A modeling study to define guidelines for antigen screening in schools and workplaces to mitigate COVID-19 outbreaks by Yong Dam Jeong, Keisuke Ejima, Kwang Su Kim, Shoya Iwanami, William S. Hart, Robin N. Thompson, Il Hyo Jung, Shingo Iwami, Marco Ajelli, Kazuyuki Aihara

    Published 2025-01-01
    “…In this study, we aim to analyze the impact of screening with antigen tests in schools and workplaces on identifying COVID-19 infections. …”
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  17. 177

    On the Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies by Andreea Calinescu, Gabriela Turcu, Roxana I. Nedelcu, Alice Brinzea, Anastasia Hodorogea, Mihaela Antohe, Carmen Diaconu, Coralia Bleotu, Daniel Pirici, Lucia B. Jilaveanu, Daniela A. Ion, Ioana A. Badarau

    Published 2018-01-01
    “…Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a glycoprotein belonging to the carcinoembryonic antigen (CEA) family that is expressed on a wide variety of cells and holds a complex role in inflammation through its alternate splicing and generation of various isoforms, mediating intricate mechanisms of modulation and dysregulation. …”
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    Scaffolded Antigens in Yeast Cell Particle Vaccines Provide Protection against Systemic Polyoma Virus Infection by Donald J. Tipper, Eva Szomolanyi-Tsuda

    Published 2016-01-01
    “…U65, a self-aggregating peptide scaffold, traps fused protein antigens in yeast cells. Conversion to Yeast Cell Particle (YCP) vaccines by partial removal of surface mannoproteins exposes β-glucan, mediating efficient uptake by antigen-presenting cells (APCs). …”
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  20. 180

    Siltuximab for chimeric antigen receptor T-cell therapy–related CRS and ICANS: a multicenter retrospective analysis by Amneet Bajwa, Qiuhong Zhao, Marcus Geer, Chenyu Lin, James Westholder, Joseph Maakaron, Monalisa Ghosh, David Frame, Ahmed Galal, Justin Tossey, Nausheen Ahmed, Evandro Bezerra, Nathan Denlinger, Marcos de Lima, Narendranath Epperla, Paolo Caimi, Timothy Voorhees

    Published 2025-01-01
    “…Abstract: Chimeric antigen receptor T-cell (CAR-T) therapies are effective in many hematologic malignancies; however, adverse events including cytokine release syndrome (CRS) and immune effector cell–associated neurotoxicity syndrome (ICANS) can affect a significant number of patients. …”
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