Women's perception of risks of adverse fetal pregnancy outcomes: a large-scale multinational survey by Irene Petersen, Hedvig Nordeng, Angela Lupattelli, Rachel L McCrea

“…The women rated cranberries and ginger least harmful (mean risk perception scores 1.1 and 1.5 of 10, respectively) and antidepressants, alcohol, smoking and thalidomide as most harmful (7.6, 8.6, 9.2 and 9.4 out of 10, respectively). …”
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Changes in Hippocampal Plasticity in Depression and Therapeutic Approaches Influencing These Changes by Wenbo Xu, Xiaoxiao Yao, Fangyi Zhao, Haisheng Zhao, Ziqian Cheng, Wei Yang, Ranji Cui, Songbai Xu, Bingjin Li

“…Studies have shown that some antidepressants can treat depression by changing the plasticity of the hippocampus. …”
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Role of Ketamine in the Treatment of Psychiatric Disorders by Sahar Derakhshanian, Maxine Zhou, Alexander Rath, Rachel Barlow, Sarah Bertrand, Caroline DeGraw, Christopher Lee, Jamal Hasoon, Alan D. Kaye

“…Current first-line treatment options are antidepressants of the selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) class. …”
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RETROSPECTIVE STUDY OF THE EFFICACY OF LONG-TERM TREATMENT OF FELINE IDIOPATHIC CYSTITIS by Anca Bărbos, Vlad Luca, Alexandra Biriș, Radu Lăcătuș

“…During the acute episode most cats received analgesics (92.86%), antibiotics (82.14%), anti-inflammatories (71.43%), antidepressants and sympatholytics with improvements in 82.14% of cases. …”
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Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary car... by Alice Malpass, Glyn Lewis, Jude Robinson, Christopher Dowrick, Naila Khan, Louise Fusco

“…Our objectives were to ascertain patients’ views on the source and meaning of mismatches and assess their clinical significance.Design Qualitative study nested within a cohort, in a programme investigating the indications for prescribing antidepressants that will lead to a clinical benefit.Setting Primary care practices in north-west England.Participants We invited 32 adults with a recent diagnosis of depression and evidence of mismatch between GRC and PHQ-9 Scores to participate. …”
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Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians. by Danielle Ireland, Christina Rabeler, Sagar Rao, Rudy J Richardson, Eva-Maria S Collins

“…In this pilot study, our goal was to classify 19 neuroactive compounds into their functional categories: antipsychotics, anxiolytics, and antidepressants. Drug classification was performed with the same computational methods, using either physicochemical descriptors or planarian behavioral profiling. …”
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Network pharmacology combined with experimental verification for exploring the potential mechanism of phellodendrine against depression by Lili Hu, Na Wu, Jue Wang, Donghui Cai

“…Our research reveals novel mechanisms underlying the anti-MDD effects of PHE through network pharmacology and experiments, which provides a new direction for the development of antidepressants.…”
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C-Reactive Protein As A Response Indicator In Drug-Naïve Patients With Major Depressive Disorder: A Hospital-Based Study by Ather Muneer, Nargis Munir, Nadia Shams, Mirza Inam, Usman Ghani, Neelam Ayub

“…Patients with first-episode MDD with no history of antidepressant exposure and other medical comorbidity were recruited for pharmacotherapy with escitalopram, a first-line antidepressant. …”
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Neuropathic pain among patients with primary knee osteoarthritis: Results of a cross-sectional study from a tertiary care center in Southern India by R Vignesh Narayan, Molly Mary Thabah, Murali Poduval

“…Centrally acting drugs such as tricyclic antidepressants or duloxetine can be used to improve the quality of life and physical function of knee OA patients with neuropathic pain.…”
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Drugs and Constipation in Elderly in Nursing Homes: What Is the Relation? by Gunvor S. Fosnes, Stian Lydersen, Per G. Farup

“…Reduced activity of daily living (OR = 0.71, 95% CI : 0.60–0.84, P<0.001), other antidepressants (N06AX) (OR 3.08, 95% CI : 1.09–8.68, P=0.03), and benzodiazepine derivatives (N05BA) (OR = 2.80, 95% CI : 1.12–7.04, P=0.03) were significantly associated with constipation; drugs with markedly anticholinergic effect (OR = 3.7, 95% CI : 0.78–17.53, P=0.10), natural opium alkaloid (N02AA) (OR = 5.01, 95% CI : 0.95–25.94, P=0.06), and propionic acid derivatives (M01AE) (OR = 7.00, 95% CI : 0.75–65.08, P=0.09) showed a trend. …”
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Trazodone effectiveness in depression: impacts of trazodone extended release vs SSRIs on the health status and quality of life of patients with major depressive disorder by Marcin Siwek, Adrian Andrzej Chrobak, Anna Julia Krupa, Aleksandra Gorostowicz, Andrzej Juryk, Dominika Dudek

“…Studies have confirmed that antidepressants generally improve the functional outcomes in MDD, but very few works have compared the efficacies of specific drugs. …”
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Physicians’ and patients’ perceived risks of chronic pain medication and co-medications in Quebec, Canada: a cross-sectional study by Gwenaëlle De Clifford-Faugère, Anaïs Lacasse, Hermine Lore Nguena Nguefack, Marimée Godbout-Parent, Aline Boulanger, Nancy Julien

“…For eight subclasses, the difference in the mean perceived risk score was > 2 points and statistically significant (p < 0.05): non-specific oral NSAIDs, acetaminophen in combination with an opioid, short-acting opioids, long-acting opioids, tricyclic antidepressants, antipsychotics, benzodiazepines, and medical cannabis. …”
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Indian Psychiatric Society multicentre study: Diagnostic patterns, comorbidity and prescription practices for patients with Dementia by CT Sudhir Kumar, Mathew Varghese, Venugopal Duddu, Sridhar Vaitheswaran, Shrikant Srivastava, KS Shaji, Sanju George, Narendra Kumar Singh, Nishant Goyal, Ajay Bakhla, S Shaji, Vikas Menon, Tajamul Hussain, Sandeep Grover, Aseem Mehra, Lokesh Kumar Singh, A Purushotham, Avinash Desousa, Nilesh Shah, Sagar Karia, I Anand, Shafana Afroon, Ritambhara Mehta, Gargi Kukreja, Dimple Dadarwala, KL Vidya, PT Sivakumar, Preeti Sinha, Shivashankar Reddy, Thomas Isaac, Mina Chandra

“…Overall, 113 (19.3%) patients were on antidepressants, 80 (13.7%) patients were on sedatives/hypnotics, and 16 (2.7%) patients were on mood stabilizers. …”
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Reduction of depressive symptoms among patients with inflammatory bowel disease treated with biological therapy: a quantitative comparative incision study by J. Zinkevičiūtė, S. Ambrasas, A. Kiziela, R. Strumila, S. Brašiškienė, E. Dlugauskas

“…Patients diagnosed with active ulcerative colitis or Crohn’s disease and not using antidepressants were included in the study. Participants were divided into an experimental group (receiving tumor necrosis factor-alpha inhibitors) and control group (receiving treatment with other drugs). …”
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Associations of Atopic Dermatitis in Late Adolescence with Occupation, Mental Health, Income from Work and Marital Status: A National Longitudinal Study by Grigorios Theodosiou, Therese Sterner, Ayako Hiyoshi, Michael Carlberg, Åke Svensson, Scott Montgomery, Laura von Kobyletzki

“…In this study, men with AD in adolescence, especially those with severe AD, more often had a prescription for antidepressants or anxiolytics at the age of 50–57 years (unadjusted HR 1.55, 95% CI 1.32–1.81). …”
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Central nervous system (CNS) medications and polypharmacy in later life: cross-sectional analysis of the English Longitudinal Study of Ageing (ELSA) by Natasha Slater, Simon White, Martin Frisher

“…The most common CNS drug classes in polypharmacy regimens were non-opioid analgesics, opioid analgesics, tricyclic and related antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) (34.6%, 13.2%, 10.9% and 10.4%, respectively). …”
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INTENSITY OF OXIDATIVE STRESS DEVELOPMENT IN RAT MAJOR CEREBRAL HEMISPHERES UNDER COMBINED CONDITIONS OF SYSTEMIC INFLAMMATORY RESPONSE, CHANGES IN THE NORMAL LIGHT-DARK CYCLE, AN... by O.A. Volkova, V.O. Kostenko

“…At present, the relevance of examining changes to the normal light-dark cycle is increasing, and the connection between the development of the systemic inflammatory response (SIR) and circadian rhythm disorders has been confirmed. The effects of antidepressants on the human body are also actively studied. …”
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Suicidality and Illness Course Worsening in a Male Patient with Bipolar Disorder during Tamoxifen Treatment for ER+/HER2+ Breast Cancer by Claudia Carmassi, Francesco Pardini, Valerio Dell’Oste, Annalisa Cordone, Virginia Pedrinelli, Marly Simoncini, Liliana Dell’Osso

“…The clinical picture showed poor response to treatment trials based on various associations of mood-stabilising, antidepressants, and antipsychotic drugs. During the second hospitalization, after a multidisciplinary evaluation, the oncologists agreed on Tamoxifen discontinuation upon the severity of the psychiatric condition. …”
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Patterns of self-harm presentations at a Tertiary Urban Hospital in Kenya: A retrospective 5-year study (2018-2022). by Willie Njoroge, Catherine Gitau, Everline Onchari, Linnet Ongeri, Linda Khakali, Murad Khan, Zul Merali, Lukoye Atwoli, Jasmit Shah

“…Analgesics were the most frequently reported type of overdose, followed by tricyclic antidepressants. In context of self-injury, cutting emerged as the predominant form of self-harm. …”
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Impact of the COVID-19 pandemic on psychotropic prescribing: a systematic review by Nikolaos Mastellos, Marie line El Asmar, Kanika I Dharmayat, Antonio J Vallejo-Vaz, Ryan Irwin, Swettha Mahesarajah

“…No particular trends were observed for the prescription rates of hypnotics, antidepressants or antipsychotics.Conclusions Findings support mixed trends in the prescription of psychotropic medications in a range of settings, hindering conclusive statements on COVID-19’s impact on prescribing. …”
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