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221
Phytochemistry and Biological Activities of Poria
Published 2021-01-01“…In this paper, we reviewed the literature, summarized the main compound types, and reviewed in detail their pharmacological effects in antitumor, immunomodulatory, effects on kidney, hepatoprotective activity, effects on blood sugar, antioxidant effects, anti-inflammatory effects, effects on the gut, antidepressant, and so on, and also categorized the compounds with the same or similar pharmacological effects to provide a reference for the in-depth study of the material basis of the pharmacological effect, quality standards, and pharmacological activity of Poria.…”
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222
Melatonin and its physiological and therapeutic effects: A review
Published 2024-01-01“…It has been proven that melatonin exerts neuroprotective and antidepressant like effects. Also, many researchers have found that melatonin plays an important role in various cardiovascular diseases. …”
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223
Neurobiology of Major Depressive Disorder
Published 2013-01-01“…Controversial issues, such as whether neurogenesis is the basis of the disease or whether it is a response induced by antidepressant treatments, are also discussed.…”
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224
Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression
Published 2025-02-01“…IntroductionKetamine demonstrates robust and rapidly occurring antidepressant effects in patients with difficult-to-treat major depressive disorder. …”
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225
Exploring the Anti-depression Mechanism of Polygonatum ordoratum Based on GEO Database Combined with Network Pharmacology and Molecular Docking Technology
Published 2025-01-01“…Results: Twenty-three antidepressant active components and 34 active targets were identified for Yuzhu. …”
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226
Do individuals with inflammatory arthritis receive minimally adequate treatment for incident depression and anxiety: A population-based study
Published 2025-01-01“…We defined minimally adequate pharmacotherapy as antidepressant prescriptions filled with ≥ 84 days’ supply and adequate psychological treatment as ≥ 4 counselling/psychotherapy services. …”
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227
Cardiovascular Side Effects of Atomoxetine and Its Interactions with Inhibitors of the Cytochrome P450 System
Published 2011-01-01“…Atomoxetine is a phenoxypropylamine derivative and is structurally related to the antidepressant fluoxetine. The common side effects reported with the use of atomoxetine include mainly GI disturbances. …”
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228
Tramadol-Induced Mood Elevation in a Patient with No Previous Psychiatric History
Published 2018-01-01“…Tramadol is a powerful analgesic medication with antidepressant effects like venlafaxine. Hypomanic features were reported in patients with psychiatric history of mood disturbance when tramadol was prescribed for them. …”
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229
Use of Methadone for Neuropathic Pain
Published 2003-01-01“…Anticonvulsant and antidepressant treatments provide effective analgesia in up to 50% of patients with chronic neuropathic pain (2) and there is a growing body of high-quality evidence that controlled-release opioid analgesics provide substantial pain relief in a further subset of patients (3-6). …”
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230
Possibilities of Using Macrolepiota procera in the Production of Prohealth Food and in Medicine
Published 2022-01-01“…The data on other health-promoting properties and the possibilities of using these mushrooms in medicine were also compiled and summarized, taking into account their antibacterial, antioxidant, anti-inflammatory, regulatory, antidepressant, and anticancer effects. Moreover, the influence of various forms of processing and conservation of raw mushroom on its health-promoting properties was discussed. …”
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231
Depression as a Neuroendocrine Disorder: Emerging Neuropsychopharmacological Approaches beyond Monoamines
Published 2019-01-01“…Currently available antidepressant drugs are notoriously problematic, with suboptimal remission rates and troubling side-effect profiles. …”
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232
New Therapeutic Targets for Mood Disorders
Published 2010-01-01“…The paper reviews data on new compounds that have shown antimanic or antidepressant effects in subjects with mood disorders, or similar effects in preclinical animal models. …”
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233
A Case of Almost Painless Herpes Zoster Presenting with Symptoms of Cystitis, Penile Numbness, and Acute Vestibular Failure
Published 2013-01-01“…Gabapentin and tricyclic antidepressant are effective in postherpetic neuralgia. …”
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234
Selective activation of SIGMAR1 in anterior cingulate cortex glutamatergic neurons facilitates comorbid pain in depression in male mice
Published 2025-01-01“…These results revealed a previously unknown neural mechanism for depression and pain comorbidity and provided new mechanistic insights into the antidepressive and analgesic effects of the disease.…”
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235
A Novel Drug-Drug Salt of Naproxen and Vortioxetine: Synthesis, Characterization, and Solubility Study
Published 2023-01-01“…Naproxen (NAP) is an aromatic propionic acid nonsteroidal anti-inflammatory drug, and vortioxetine (VOT) is a novel antidepressant drug. In this study, a new 1 : 1 drug-drug salt of NAP and VOT (namely, NAP-VOT) was designed and synthesized by liquid-assisted grinding and slow evaporation. …”
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236
Longitudinal Course of Illness in Congenitally Deaf Patient with Auditory Verbal Hallucination
Published 2022-01-01“…His psychotic symptoms decreased when his primary medication was changed from an antidepressant to antipsychotic drugs, based on the change of diagnosis. …”
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237
YELLOW CAMELLIAS: A REVIEW OF CHEMICAL CONSTITUENTS AND BIOLOGICAL ACTIVITIES
Published 2022-04-01“…Many pharmacological studies have proved that the total extracts, fractions, and isolated substances from yellow camellia species possess antioxidant, anticancer, hypolipidemic, hypoglycemic, antiallergic, hepatoprotective, neuroprotective, anxiolytic, and antidepressant activities. This review systematically summarizes recent research results in order to provide a comprehensive and up-to-date understanding of the chemical composition and biological activities of yellow camellia species, creating a basis for research of the yellow camellia species in Vietnam and development of new products from this source.…”
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238
Occurrence, properties and biological significance of pyroglutamyl peptides derived from different food sources
Published 2019-09-01“…Moreover, some health-promoting properties have been reported for pGlu peptides, including hepatoprotective, antidepressant and anti-inflammatory activities. However, the role of pGlu residue in the peptide bioactivity is not completely established, although the hydrophobic γ-lactam ring is thought to enhance the peptide stability against degradation by gastrointestinal proteases. …”
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239
Anxiety and depression in people with epilepsy during and one year after the COVID‐19 pandemic
Published 2025-02-01“…The only significant finding was that patients on anxiolytic or antidepressant medication had lower scores for anxiety and depression. …”
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240
Prediction of individual patient outcomes to psychotherapy vs medication for major depression
Published 2025-02-01“…Abstract Treatments for major depressive disorder (MDD) include antidepressant medications and evidence-based psychotherapies, which are approximately equally efficacious. …”
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