Treatment Options for Psychotic Depression in Adolescents: A Comprehensive Review by Perez-Rodriguez V, Aymerich C, Catalan A, Jauhar S, Salazar de Pablo G

“…In severe presentations, antidepressant-antipsychotic combination would be the treatment of choice. …”
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Low molecular mass chondroitin sulfate suppresses chronic unpredictable mild stress-induced depression-like behavior in mice by Si Xiao-Ming, Tian Yu-Hua, Zhang Sha-Sha, Gao Hua, Liu Kun, Jin Jing-Yu

“…The present study is aimed at testing the antidepressant--like effects and probable mechanisms of action of low molecular mass chondroitin sulfate (LMMCS) on depression induced by chronic unpredictable mild stress (CUMS) in mice. …”
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Transient Serotonin Toxicity Evoked by Combination of Electroconvulsive Therapy and Fluoxetine by René Klysner, Birgitte Bjerg Bendsen, Maja Soon Hansen

“…The serotonin syndrome has been described only in rare instances for electroconvulsive therapy combined with an antidepressant medication. We describe a case of serotonin toxicity induced by electroconvulsive therapy in combination with fluoxetine.…”
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Modulation of the endocannabinoid system by (S)-ketamine in an animal model of depression by Nicole R. Silva, Shokouh Arjmand, Luana B. Domingos, Adriano M. Chaves-Filho, Melina Mottin, Caroline C. Real, Anna L. Waszkiewicz, Pedro H. Gobira, Alessio Nicola Ferraro, Anne M. Landau, Carolina H. Andrade, Heidi K. Müller, Gregers Wegener, Sâmia R.L. Joca

“…Ketamine (KET) is recognized as rapid-acting antidepressant, but its mechanisms of action remain elusive. …”
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Monoamines, BDNF, Dehydroepiandrosterone, DHEA-Sulfate, and Childhood Depression—An Animal Model Study by O. Malkesman, T. Asaf, L. Shbiro, A. Goldstein, R. Maayan, A. Weizman, N. Kinor, E. Okun, B. Sredni, G. Yadid, A. Weller

“…In the second phase, we examined the responsiveness of prepubertal WKY rats to different types of chronic antidepressant treatments: Fluoxetine, Desipramine, and dehydroepiandrosterone sulfate (DHEAS). …”
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Crack Cocaine-Induced Cardiac Conduction Abnormalities Are Reversed by Sodium Bicarbonate Infusion by Carlos Henrique Miranda, Antônio Pazin-Filho

“…During this intoxication, electrocardiographic abnormalities similar to those found in tricyclic antidepressant poisoning were observed, and they were reversed by intravenous sodium bicarbonate infusion.…”
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Are Selective Serotonin Reuptake Inhibitors a Secondary Cause of Low Bone Density? by Kim Chau, Stephanie A. Atkinson, Valerie H. Taylor

“…Both depression and antidepressant use have been identified as secondary causes of osteoporosis. …”
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Tea and depression by Klaus W. Lange, Yukiko Nakamura, Katharina M. Lange, Hui Zhao

“…A wide range of potentially antidepressive biological activities of tea components have been reported. …”
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Morinda officinalis oligosaccharides alleviate chronic unpredictable mild stress-induced depression through the BDNF/TrkB/CREB pathway and symptoms of sexual dysfunction in mice by Mengjie He, Mengying Hu, Tingqiao Wang, Zeping Zuo, Hongkai Li, Zhiwei Zhao, Yunwen Hao, Xueling Dai, Jianfang Wang, Yaxuan Sun

“…MOO further confirmed that sexual dysfunction is closely related to the development of depression by improving the lack of sexual motivation and low sexual performance in CUMS-induced depressed mice, modulating the disruption of sex hormone secretion in serum, and alleviating sperm morphology and functional defects in the epididymis.ConclusionThese findings on MOO provide a basis for exploring its antidepressant mechanism, its use to improve hypogonadotropic symptoms, and for future development of new antidepressant drug to improves hypogonadotropic symptoms.…”
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Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature by Lampros Samartzis, Paraskevi Savvari, Sofoklis Kontogiannis, Stavros Dimopoulos

“…We report a unique case of an adverse interaction between the oxazolidinone antibiotic linezolid, the tricyclic antidepressant amitriptyline and the opioid analgesic fentanyl in a 68-year-old woman with advanced ischemic peripheral arterial disease and sepsis, under empirical antibiotic treatment. …”
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Muscle Relaxant and Sedative-Hypnotic Activities of Extract of Viola betonicifolia in Animal Models Supported by Its Isolated Compound, 4-Hydroxy Coumarin by Naveed Muhammad, Mohammad Saeed, Haroon Khan, Achyut Adhikari, Khalid Mohammed Khan

“…The crude methanolic extract of the whole plant of Viola betonicifolia (VBME) was investigated for anxiolytic, muscle relaxant, sleep induction, antidepressant, and sedative activities) to ascertain its scientific values. …”
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Citrus aurantium L. extract alleviate depression by inhibiting gut microbiota-mediated inflammation in mice by Tao Li, Guirong Zeng, Lingfeng Zhu, Yanyang Wu, Qun Zhang, Fuhua Fu, Donglin Su, Gaoyang Li, Qili Li, Yang Shan

“…This study aimed to explore the antidepressant effect of mature whole Citrus aurantium fruit extract (FEMC) in the chronic unpredictable mild stress (CUMS) model. …”
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A Comparative Study on the Effectiveness of Electroconvulsive Therapy and Ketamine in Persons Suffering from Treatment-resistant Depressive Disorder by Vikhram Ramasubramanian, S. Mathumathi, Gautami Thirumalaisamy, Sugaparaneetharan Ayyanar, Gopi Rajendhiran, M. Kannan

“…Patients with major depression respond to antidepressant treatment, but 10%–20% of them do not improve or show a partial response. …”
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The Impact of Abnormal Glucose Tolerance and Obesity on Fetal Growth by Erin Graves, David J. Hill, Susan Evers, Kristine Van Aarsen, Brie Yama, Su Yuan, M. Karen Campbell

“…High prepregnancy BM, height, antidepressant use, pregnancy weight-gain exceeding 40 pounds, and high blood sugar were associated with LGA birth, but not necessarily infant weight/length ratio. …”
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Comparative Pharmacokinetic Study of Three Major Bioactive Components in the Normal and Different Courses of Liver-Stagnation and Spleen-Deficiency Syndrome Depressive Rats after I... by Kaiwen Luo, Mengdie Wang, Xiangxiang Pan, Yadong Xing

“…This study provided important information for the clinical rational use of ZZHPD in antidepressant treatment.…”
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The promise and challenges of pharmacogenomics in psychiatry by Elaine Ah Gi Lo, Yi Min Wan, Cyrus Su Hui Ho

“…The remission rate for the initial antidepressant prescribed in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial was only approximately 30%, underscoring the need for more personalised approaches to prescribing.1 For psychiatric patients who may show resistance towards pharmacotherapy, PGx offers promise in reducing adverse effects and enhancing therapeutic efficacy. …”
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Radix Scutellariae Ameliorates Stress-Induced Depressive-Like Behaviors via Protecting Neurons through the TGFβ3-Smad2/3-Nedd9 Signaling Pathway by Fan Zhao, Chenyiyu Zhang, Dong Xiao, Weihua Zhang, Liping Zhou, Simeng Gu, Rong Qu

“…These results suggest that RS could exert antidepressant effects via protecting neurons. And the molecular mechanism might be related to the regulation of the TGFβ3-SMAD2/3-NEDD9 pathway.…”
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Hybrid electroconvulsive therapy in an adolescent with major depressive disorder: a case report by Jing-ya Zhang, Jia Li, Nan Wang, Xin-hui Xie, Xin-hui Xie, Lun Zeng

“…Here, we report a case study of a 14-year-old male student with major depressive disorder (MDD) suffering from severe suicidality and significant impairment in social functioning who achieved effective antidepressant effects with HECT and improved cognitive function. …”
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Pseudopheochromocytoma Associated with Domestic Assault by H. M. Le, G. Carbutti, D. Ilisei, E. Bouccin, X. Vandemergel

“…Treatment of pseudopheochromocytoma can be challenging due to normal blood pressure values in between the hypertensive peaks; it includes alpha- and beta-blockers for moderate crises and prevention and must be combined with psychopharmacologic agents such as anxiolytics or antidepressant drugs. Psychotherapy and dietetic treatment are also crucial in pseudopheochromocytoma management.…”
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Diffuse Hair Loss Induced by Sertraline Use by Yüksel Kıvrak, İbrahim Yağcı, Mehmet Fatih Üstündağ, Halil Özcan

“…Sertraline is a potent antidepressant which inhibits the serotonin reuptake from the presynaptic terminals selectively. …”
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