Correlation Between Vitamin D3 Levels, Autoantibodies, and Antibody-Related Diseases in Patients with Hashimoto's Thyroiditis by Ali Saad Kadhim, Abdullah Salim Al-Karawi

Subjects: Get full text

Erratum to “Anti-Interleukin-22-Neutralizing Antibody Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Mice” by Jing Ye, Ling Liu, Qingwei Ji, Ying Huang, Ying Shi, Lei Shi, Jianfang Liu, Menglong Wang, Yao Xu, Huimin Jiang, Zhen Wang, Yingzhong Lin, Jun Wan

Get full text

Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1 by Pauline Malinge, Xavier Chauchet, Jérémie Bourguignon, Nicolas Bosson, Sébastien Calloud, Tereza Bautzova, Marie Borlet, Mette Laursen, Vinardas Kelpsas, Nadia Rose, Franck Gueneau, Ulla Ravn, Giovanni Magistrelli, Nicolas Fischer

“…In contrast to natural antibodies that rely mainly on the heavy chain to establish contacts with their cognate antigen, we have developed a bispecific antibody format in which the light chain (LC) drives antigen binding and specificity. …”
Get full text

Germinal Center B Cells are Uniquely Targeted by Antibody-Suppressor CXCR5+CD8+ T Cells by Jason M. Zimmerer, PhD, Sachi Chaudhari, BS, Kavya Koneru, BS, Jing L. Han, MD, PhD, Mahmoud Abdel-Rasoul, MA, Hope Uwase, MA, Tai Yi, MD, Christopher K. Breuer, MD, Ginny L. Bumgardner, MD, PhD

“…Background. Alloprimed antibody-suppressor CXCR5+CD8+ T cells (CD8+ TAb-supp cells) downregulate alloantibody production, mediate cytotoxicity of IgG+ B cells, and prolong allograft survival. …”
Get full text

Effects of Thyroid Peroxidase Antibody on Maternal and Neonatal Outcomes in Pregnant Women in an Iodine-Sufficient Area in China by Xi Chen, Bai Jin, Jun Xia, Xincheng Tao, Xiaoping Huang, Lu Sun, Qingxin Yuan

“…To evaluate the effects of thyroid peroxidase antibodies (TPOAb) on maternal and neonatal adverse outcomes in pregnant women. …”
Get full text

Antineutrophil Cytoplasmic Antibody Induction due to Infection: A Patient with Infective Endocarditis and Chronic Hepatitis C by Fareed B. Kamar, T. Lee-Ann Hawkins

“…While antineutrophil cytoplasmic antibody (ANCA) is often used as a diagnostic marker for certain vasculitides, ANCA induction in the setting of infection is much less common. …”
Get full text

Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration by Paul Tamburini, Dennis Vestergaard Pedersen, Denise Devore, Josh Cone, Rekha Patel, Todd Hunter, Fang Sun, Gregers Rom Andersen, Jeffrey Hunter

Subjects: “…Bispecific VHH antibody…”
Get full text

Diagnostic Performance of Three ELISAs for Detection of Antibodies against SARS-CoV-2 in Human Samples by Cássio Meira, Dahara Silva, Ivanilson Santos, Breno Barreto, Vinícius Rocha, Emanuelle Santos, Bruna dos Reis, Afrânio Evangelista, Ricardo Ribeiro dos Santos, Bruna Machado, Guilherme Ribeiro, Roberto Badaró, Milena Soares

“…The accuracy assessment indicated the N protein (accuracy = 0.98) as the antigen most likely to give a correct diagnosis. Overall, the antibody responses were present for all three proteins in subjects with confirmed SARS-CoV-2 infections, showing a similar pattern of antibody production for different antigens. …”
Get full text

Antibody and serum bactericidal response to Burkholderia pseudomallei in acute localized and septicemic melioidosis cases with diabetes mellitus by Sraboni Mazumder, Md. Shariful Alam Jilani, Lovely Barai, KM Shahidul Islam

“…Out of 10 cases, 9 (90%) were positive for serum bactericidal antibody. Mean serum bactericidal antibody titer of septicemia cases (66 ± 26) was not significantly (p = 0.72) different than those of localized infection (80 ± 28.28). …”
Get full text

Small-Cell Lung Cancer with Positive Anti-NMDAR and Anti-AMPAR Antibodies Paraneoplastic Limbic Encephalitis by Sabina Boangher, Pascal Mespouille, Corina-Mihaela Filip, Sophie Goffette

“…The patient presented to the emergency room with rapidly increasing symptoms, noninfectious cerebral spinal fluid associated with positive anti-NMDAR (as well as in serum) and positive AMPAR antibodies in the serum. Four months later, the patient was diagnosed with a small-cell lung cancer for which chemotherapy and radiotherapy was commenced. …”
Get full text

The Impact of Intermediate Antidrug Antibodies to Infliximab and Adalimumab on Clinical Outcomes in Patients with Crohn’s Disease or Ulcerative Colitis by Chaoyang Wang, Mazen Tolaymat, Raymond Cross

“…However, 40% of patients lose response, often due to the development of antibodies-to-ADA (ATA) and antibodies-to-IFX (ATI). …”
Get full text

Antibody Responses to mRNA COVID-19 Vaccine Among Healthcare Workers in Outpatient Clinics in Japan by Teruhime Otoguro, Keita Wagatsuma, Toshiharu Hino, The Society of Ambulatory and General Pediatrics of Japan, Yusuke Ichikawa, Tri Bayu Purnama, Yuyang Sun, Jiaming Li, Irina Chon, Hisami Watanabe, Reiko Saito

Subjects: Get full text

Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG1 antibody by Jing Dai, Saeed Izadi, Jonathan Zarzar, Patrick Wu, Angela Oh, Paul J. Carter

Subjects: “…Antibody…”
Get full text

Maternal F1 antibodies and cytokines in mother-neonate dog pairs in the Marmota himalayana plague focus by Deming Tang, Asaiti Bukai, Shuai Qin, Ran Duan, Dongyue Lyu, Zhaokai He, Xiaojin Zheng, Weiwei Wu, Junrong Liang, Haifu Qu, Aidai Bieke, Peng Zhang, Dan Zhang, Haonan Han, Qun Duan, Huaiqi Jing, Xin Wang

Subjects: Get full text

Use of Anti-Interleukin-6 Receptor Monoclonal Antibody in Drug-Induced Acute Respiratory Distress Syndrome by Alessandra Petrillo, Noa Biran, Sean Sadikot

“…We discuss a case of a patient with multiple myeloma who was hospitalized with drug-induced ARDS who had a rapid response to an anti-interleukin-6 monoclonal antibody.…”
Get full text

Design of indirect ELISA-based test-system for determination of Mannheimia haemolytica antibody titre in bovine sera by Ye. S. Kostrova, O. P. Bjadovskaya, Ye. V. Peshkova, O. V. Pruntova

“…Indirect ELISA-based test-system was developed for determination of Mannheimia haemolytica antibody titre in sera from cattle of different age-sex groups. …”
Get full text

Exploring the clinical significance of anti-acetylcholine receptor antibody titers, changes, and change rates in Myasthenia Gravis by Lijun Luo, Xinyi Zhu, Chunbei Wen, Yifan Guo, Jie Yang, Dongsheng Wei, Ping Yu, Mei Wan

Subjects: “…acetylcholine receptor antibody titers…”
Get full text

Factors associated with the formation of neutralizing antibodies post-vaccination: a lesson from COVID-19 vaccination by Hana Ratnawati, Fen Tih, Grace Puspasari, Allen A. Pelapelapon, Steven Felim

Subjects: “…neutralizing antibodies…”
Get full text

High Grade Glioma Mimicking Voltage Gated Potassium Channel Complex Associated Antibody Limbic Encephalitis by Dilan Athauda, R. S. Delamont, E. De Pablo-Fernandez

“…We describe a patient with a high grade glioma presenting with clinical, radiological, and serological features consistent with the diagnosis of VGKC antibody associated limbic encephalitis (LE). This is the first association between a primary brain tumour and high titre of VGKC complex antibodies. …”
Get full text

Presence of Serum Antinuclear Antibodies Does Not Impact Outcomes in HBV-Related Acute-on-Chronic Liver Failure by Lin Lin, Bin Lin, Qing Lan, Longgen Liu, Jianchun Lu, Xiujun Zhang, Shuqin Zheng, Yuan Xue

“…The aim of this study was to provide new insights into the prevalence of positive antinuclear antibody (ANA) in patients with HBV-related acute-on-chronic liver failure (ACLF) and its impact on clinical outcomes. …”
Get full text