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3461
Mutations in the <i>A34R</i> gene increase the immunogenicity of vaccinia virus
Published 2021-04-01“…It was shown that increase in EEV production by recombinant strain VACV LIVP-GFP-A34R does not change the attenuated phenotype characteristic of the parental strain LIVP-GFP, but causes a significantly larger production of VACV-specific antibodies.…”
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3462
Efficacy and Safety of Ergoferon in Children from 6 Months to 6 Years Old with Acute Respiratory Viral Infections in Contemporary Outpatient Practice: A Multicenter, Double-Blind,...
Published 2021-01-01“…Derived by technological treatment of antibodies to interferon gamma, histamine, and CD4, Ergoferon was previously proved to modulate its molecular targets promoting effective antiviral protection. …”
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3463
Prognostic importance of human leukocyte antigen DRβ1 gene and protein tyrosine phosphatase nonreceptor Type 22 gene polymorphism in rheumatoid arthritis
Published 2017-01-01“…HLA DRβ1 typing was done by low-resolution sequence-specific primer polymerase chain reaction and auto-antibodies (Abs) (rheumatoid factor [RF], anti-cyclic citrullinated peptide 2 (CCP2) Ab, anti-nuclear Ab, double-stranded deoxyribose nucleic acid, anticardiolipin Ab) were done by enzyme-linked immunosorbent assay. …”
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3464
Thyroid Hormone Changes in the Northern Area of Tianjin during the COVID-19 Pandemic
Published 2022-01-01“…The detection rate of abnormal thyroid function was decreased in pandemic Group B (69.2% vs. 93.3%, χ2 = 42.725, p<0.01), especially for hypothyroidism (14.29% vs. 35.71%, χ2 = 27.429, p<0.01) and isolated thyroid-related antibodies (25.89% vs. 38.39%, χ2 = 8.023, p<0.01). …”
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3465
Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications
Published 2025-01-01“…Furthermore, therapeutic strategies targeting CHI3L1, such as small-molecule inhibitors and neutralizing antibodies, have shown promise in preclinical studies, demonstrating reduced neuroinflammation, amyloid plaque accumulation, and improved neuronal survival. …”
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3466
Geospatial distribution of Hepatitis E seroprevalence in Nepal, 2021.
Published 2024-12-01“…Limited surveillance capacity and suboptimal access to diagnostics leads to under-reporting of HEV infections in affected countries, including Nepal. Serum antibodies against HEV are indicative of past infection. …”
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3467
Patient-reported systemic symptoms in women with silicone breast implants: a descriptive cohort study
Published 2022-06-01“…Furthermore, 56% reported pre-existing allergies at baseline and positive antinuclear antibodies were observed in 23%. At follow-up with a median of 3.3 years (IQR 2–4), 152 women had their implants removed on clinical grounds. …”
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3468
Seroprevalence of transfusion-transmissible infections among family replacement donors and voluntary non-remunerated blood donors during the COVID-19 pandemic in sub Saharan Africa
Published 2024-01-01“…The Rapid Plasma Reagent test was used to find out treponemal antibodies. The determination of ABO and Rh blood groups was performed using monoclonal antisera following classical hemagglutination test on a plate. …”
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3469
Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells.
Published 2025-01-01“…CD8+ T-cells CM was collected after five days of cell activation using anti-CD3/CD28 antibodies and interleukin-2 (IL-2). CD8+ T-cells were activated for 72 hours and then cultured with the hypoxic PANC-1 CM.…”
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3470
Contradictory Effect of Lymphocyte Therapy and Prednisolone Therapy on CD3+CD8+CD56+ Natural Killer T Population in Women with Recurrent Spontaneous Abortion
Published 2023-07-01“…Conclusion: The lower capability of LIT in changing the population of NKT cells compared to prednisolone therapy may be due to its mechanism of action, which is related to the production of blocking antibodies. These treatment approaches had different effects on NKT cells, indicating that NKT cell population and function can be affected using LIT and prednisolone therapy distinctly. …”
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3471
Genetic diversity of the immunoglobulin heavy chain locus in cohorts of patients affected with SARS-CoV-2
Published 2025-01-01“…Abstract Background The Immunoglobulin Heavy Chain (IGH) genomic region is responsible for the production of circulating antibodies and warrants careful investigation for its association with COVID-19 characteristics. …”
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3472
Diagnosis and treatment of descending optic neuritis developed as a manifestation of local viral encephalitis (a clinical case)
Published 2022-11-01“…</p> <p> <b>Keywords</b>: optical neuritis, encephalitis, herpes virus, markers, antibodies, vesicles, ophthalmoscopy, perimetry. </p> <i><b>For citation: </b>Korsakova N.V., Korsakova E.I. …”
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3473
Prevalence and Risk Factors of Human Herpes Virus Type 8 (HHV-8), Human Immunodeficiency Virus-1 (HIV-1), and Syphilis among Female Sex Workers in Malindi, Kenya
Published 2019-01-01“…A total of 268 FSWs consented and were administered a structured questionnaire and screened for antibodies against HHV-8, HIV, and syphilis following the National Guidelines. …”
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3474
The efficacy of cholecalciferol in the comprehensive treatment of patients with autoimmune diabetes
Published 2024-12-01“…A comprehensive evaluation of carbohydrate metabolism indicators (fasting glycemia, HbA1c, HOMA-IR, insulin, and C-peptide levels), autoimmune activity (antibodies to glutamic acid decarboxylase (antiGAD)), and lipid profile was conducted before and after treatment. …”
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3475
Seroprevalence and Associated Risk Factors of Foot and Mouth Disease in Cattle in West Shewa Zone, Ethiopia
Published 2020-01-01“…A total of 384 sera samples were collected from randomly selected cattle and tested using ELISA for antibodies against nonstructural proteins of foot and mouth disease viruses based on IDEXX FMD Multispecies Ab Test (IDEXX Laboratories Inc, USA). …”
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3476
Intranigral Administration of β-Sitosterol-β-D-Glucoside Elicits Neurotoxic A1 Astrocyte Reactivity and Chronic Neuroinflammation in the Rat Substantia Nigra
Published 2020-01-01“…We injected 6 μg BSSG/1 μL DMSO or vehicle into the left substantia nigra and immunostained with antibodies against tyrosine hydroxylase (TH) together with markers of microglia (OX42), astrocytes (GFAP, S100β, C3), and leukocytes (CD45). …”
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3477
Clinicopathological and Prognostic Significance of CD47 Expression in Lung Neuroendocrine Tumors
Published 2021-01-01“…Recent clinical trials have indicated that inhibition of CD47 with anti-CD47 antibodies exerts a promising antitumor effect against several human malignancies, including NSCLC, melanoma, and hematologic malignancies. …”
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3478
Evaluation of IgG binding capability to SARS-CoV-2 variants in early COVID-19 convalescent sera using an indirect ELISA
Published 2025-02-01“…The RBD and full-length spike of SARS-CoV-2 are the main targets of the neutralizing antibodies (mainly IgGs). Many SARS-CoV-2 variants are considered to have potential to escape from the host immune system. …”
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3479
Revealing viral hepatitis epidemiology in the Democratic Republic of Congo: insights from yellow fever surveillance reanalysis
Published 2025-02-01“…Samples from individuals testing negative for yellow fever were tested for IgM antibodies against HAV, HBc, HCV, and HEV and HBs antigen using validated ELISA kits. …”
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3480
Impact of HIF-1α, LOX and ITGA5 Synergistic Interaction in the Tumor Microenvironment on Colorectal Cancer Prognosis
Published 2025-01-01“…<b>Methods</b>: HIF-1α, LOX and ITGA5 antibodies were applied immunohistochemically to tissue microarrays prepared from tumor samples. …”
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