-
3381
HEAL-Dengue: Hospital- based Exploration, Analysis and Learning about Dengue Outcomes (HEAL-D-ALDO)
Published 2025-02-01“…Methodology: A total of 215 patients presenting with characteristic symptoms and NS1 antigen and IgM. Anti Dengue antibodies positivity were included in current study. …”
Get full text
Article -
3382
Can GastroPanel be used as a triage tool to select patients with advanced atrophic gastritis for gastroscopy? A prospective clinical validation study
Published 2025-01-01“…GastroPanel (Biohit Oyj; Helsinki, Finland) is an ELISA kit that measures pepsinogen I (PGI); pepsinogen II (PGII); gastrin-17 (G-17); and Helicobacter pylori IgG antibodies (Hp IgG). PGI and the PGI/PGII ratio correlate inversely with the severity of chronic atrophic gastritis (AG). …”
Get full text
Article -
3383
Unveiling the potential of spirulina algal extract as promising antibacterial and antibiofilm agent against carbapenem-resistant Klebsiella pneumoniae: in vitro and in vivo study
Published 2025-01-01“…Using immunohistochemical investigations, the percentage of the immunoreactive cells significantly decreased after using monoclonal antibodies of the tumor necrosis factor-alpha and interleukin six. …”
Get full text
Article -
3384
A literature review of recent advances in gastric cancer treatment: exploring the cross-talk between targeted therapies
Published 2025-01-01“…Main body This review examines over 160 clinical studies conducted globally, focusing on the effectiveness of various immunotherapy modalities, including cancer vaccines, adoptive cell therapy, immune checkpoint inhibitors (ICIs), and monoclonal antibodies (mAbs). A comprehensive search of peer-reviewed literature was performed using databases such as Web of Science, PubMed, and Scopus. …”
Get full text
Article -
3385
Colostrum avoidance and associated factors among postnatal mothers in health facilities in Addis Ababa, Ethiopia: a mixed method study
Published 2025-01-01“…It is highly nutritious and contains antibodies to protect the newborn against disease and crucial for the newborn’s health Despite its benefits, some mothers avoid giving colostrum to their newborns. …”
Get full text
Article -
3386
Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis
Published 2023-08-01“…When analysing anti-citrullinated protein antibodies, RF isotype determination increases diagnostic accuracy. …”
Get full text
Article -
3387
Graves’ disease diagnosed nearly six months after microwave ablation of benign thyroid nodules: a case report
Published 2025-01-01“…The patient had elevated serum thyroid hormone levels, decreased thyroid-stimulating hormone levels and positive associated thyroid antibodies. To control the symptoms of hyperthyroidism, the patient opted for oral antithyroid medication, and thyroid hormonal levels returned to normal after 3 months of treatment. …”
Get full text
Article -
3388
Integrated omics profiling of individual variations in intestinal damage to the soybean allergen in piglets
Published 2025-01-01“…Moreover, the levels of inflammatory factors (IL-1β, IL-4, TNF-α) and antibodies (IgG, IgE, and specific IgG) in allergic piglets were significantly higher than those in non-allergic piglets (P < 0.05). …”
Get full text
Article -
3389
Gastric Precancerous Lesions: From Progenitor Cell and Microsatellite Instability to Clinical Interpretation of Gastric Cancer Risk
Published 2024-10-01“…Gastrobiopsy specimens were examined histologically, immunohistochemically using mouse monoclonal antibodies (Diagnostic BioSystems, USA) to the MMR system proteins: MLH-1 (clone G168-15, dilution 1:50), MSH2 (clone DBM15.82, dilution 1:100), MSH6 (clone 44, dilution 1:50), PMS2 (clone A16-4, ready to use). …”
Get full text
Article -
3390
Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn
Published 2024-12-01“…Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended serum half-life, achieved through pH-dependent binding to the neonatal Fc receptor (FcRn). …”
Get full text
Article -
3391
Causal Mediation Analyses for the Natural Course of Hepatitis C: A Prospective Cohort Study
Published 2025-01-01“…HCV infection was profiled by antibodies against HCV and HCV RNA in participants’ serum samples. …”
Get full text
Article -
3392
IgE-based analysis of sensitization and cross-reactivity to yellow mealworm and edible insect allergens before their widespread dietary introduction
Published 2025-01-01“…Sensitization to TM was most commonly associated with a positive response to house cricket and migratory locust allergens. sIgE antibodies against TM significantly more commonly (p < 0.001) co-occurred with sIgE against other invertebrate allergens. …”
Get full text
Article -
3393
Pancreatic Cancer: Molecular, Biochemical, Chemopreventive, and Therapeutic Aspects
Published 2010-01-01“…The inhibition of signal pathways can be carried out not only by small molecules, able to bind to selected regions of the target protein, but also by using large molecules as antibodies. The pathway to successful new therapies has been inhibited because of the rapidity with which agents tend to move into randomized, controlled trials without the extensive early testing necessary to optimize treatment regimens. …”
Get full text
Article -
3394
Pancreas Proapoptotic Proteases in Patients with Chronic Pancreatitis
Published 2019-06-01“…Immunohistochemical typing of proapoptotic proteases was performed according to the indirect avidin-streptavidin-peroxidase reaction (“Elite”, USA) using rabbit antibodies to DNA-I and endonuclease-G (“Chemicon”, USA, 1: 500 dilution — 1: 2000, incubation 12:00, + 4 °С).Results. …”
Get full text
Article -
3395
Latent Toxoplasmosis among Breast Cancer Patients in Jahrom, South of Iran
Published 2023-01-01“…One hundred and seven women with breast cancer (aged 34 to 80 years) were screened for anti-T. gondii antibodies (IgG and IgM) during 2019–2020. A questionnaire regarding demographic factors was filled out by participants. …”
Get full text
Article -
3396
Immunolipid magnetic bead-based circulating tumor cell sorting: a novel approach for pathological staging of colorectal cancer
Published 2025-01-01“…ObjectiveThis study aimed to assess whether circulating tumor cells (CTCs) from colorectal cancer (CRC) could be used as an alternative to tissue samples for genetic mutation testing, overcoming the challenge of difficult tumor tissue acquisition.MethodsWe developed an immunolipid magnetic bead (IMB) system modified with antibodies against epithelial cell adhesion molecule (EpCAM) and vimentin to efficiently separate CTCs. …”
Get full text
Article -
3397
Assessment of left ventricle myocardial performance index (Tei index) by myocardial tissue Doppler imaging and its correlation with serum thyroid-stimulating hormone levels and ath...
Published 2024-12-01“…After taking consent, all eligible patients underwent tests for routine blood sampling, lipid profile, thyroid profile, antithyroid peroxidase antibodies, electrocardiography, and echocardiography including tissue Doppler imaging. …”
Get full text
Article -
3398
Integrated Serosurveillance of Infectious Diseases Using Multiplex Bead Assays: A Systematic Review
Published 2025-01-01“…Integrated serological surveillance (serosurveillance) involves testing for antibodies to multiple pathogens (or species) simultaneously and can be achieved using multiplex bead assays (MBAs). …”
Get full text
Article -
3399
Clinicopathological and Sero-Molecular Detection of Mycoplasma capricolum subsp. capripneumoniae in Goats in Southern Areas of Pakistan
Published 2022-01-01“…A commercial competitive ELISA kit confirmed anti-Mccp antibodies in altogether 17% of serum samples, while area-wise seroprevalence was recorded as follows: Kohat, 28%, Bannu, 18%, DI Khan, 14%, and Karak, 8%. …”
Get full text
Article -
3400
Application of efgartigimod in Chinese patients with myasthenia gravis: a single-center real-world prospective study
Published 2025-01-01“…During the 8-week follow-up, in GMG patients, whether positive for acetylcholine receptor (AChR) or muscle-specific tyrosine kinase (MuSK) antibodies, the overall efficacy was significant. Within one treatment cycle, 18 (82%) patients showed a reduction of at least 2 points in MG-ADL scores and sustained for at least 4 weeks, and 6 (27%) attained minimal symptom expression (MSE) and sustained for at least 4 weeks. …”
Get full text
Article