Differential diagnosis of rheumatic manifestations of acromegaly. Case report by Margarita A. Perepelova, Larisa K. Dzeranova, Taras S. Panevin, Elena G. Przhiyalkovskaya, Ekaterina A. Pigarova, Ekaterina A. Troshina, Evgeniy G. Zotkin

“…As part of the examination, an increase in the titer of the antinuclear factor (1/2560) and the level of antibodies to ribonucleoprotein was revealed, which is most typical for mixed connective tissue disease. …”
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Elevated BP180 ELISA at Diagnosis Correlates with Disease Severity and Relapse in Oral Mucous Membrane Pemphigoid: Preliminary Results from a Retrospective Monocentric Italian Stud... by Andrea Gabusi, Davide B. Gissi, Roberto Rossi, Federica Filippi, Camilla Loi, Cosimo Misciali, Giacomo Clarizio, Michelangelo La Placa, Federico Bardazzi

“…The aim of the present study was to investigate if the levels of anti-BP180 antibodies at diagnosis could be correlated with clinical severity and relapse. …”
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Canadian Public Health Laboratory Network laboratory Guidelines for the Use of Serological Tests (excluding point-of-care tests) for the Diagnosis of Syphilis in Canada by Paul N Levett, Kevin Fonseca, Raymond SW Tsang, Kamran Kadkhoda, Bouchra Serhir, Sandra M Radons, Muhammad Morshed

“…Some of the issues related to serological diagnoses are that antibodies take time to appear after infection, and serology screening tests require several secondary confirmatory tests that can produce complex results needing interpretation by experts in the field. …”
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Microscopic Observation of Proliferative Membranes in Fibrocontractive Retinal Disorders by Rino Frisina, Francesco Tessarolo, Ivan Marchesoni, Federico Piccoli, Emiliana Bonomi, Patrizio Caciagli, Edoardo Midena, Giandomenico Nollo

“…Immunohistochemical staining was performed with antibodies to alpha smooth muscle actin and CD68. Data were analyzed after grouping according to the following tissue types: ILM (20 specimens), epiretinal membrane (ERM) (22 specimens), ILM + ERM (20 specimens), and proliferative vitreoretinopathy (PVR) (7 specimens). …”
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Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis by Anna Popławska-Kita, Beata Telejko, Katarzyna Siewko, Maria Kościuszko-Zdrodowska, Natalia Wawrusewicz-Kurylonek, Adam Krętowski, Justyna Hryniewicka, Janusz Dzięcioł, Witold Bauer, Robert Milewski, Małgorzata Szelachowska, Maria Górska

“…In the HT group Tg mRNA expression correlated positively with NIS mRNA expression (R=0.739, P=0.0001) and thyroid volume (R=0.465, P=0.0005), as well as negatively with TNFα mRNA expression (R=-0.490, P=0.001) and anti-peroxidase antibodies (TPOAb) level (R=-0.482, P=0.0002), whereas NIS mRNA expression correlated positively with thyroid volume (R=0.319, P=0.02), as well as negatively with TNFα mRNA expression (R=-0.529, P=0.0006) and TPOAb level (R=-0.422, P=0.001). …”
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β-Glucan induced plasma B cells differentiation to enhance antitumor immune responses by Dectin-1 by Yu Bai, Jun Ding, Liuyang He, Zhichao Zhu, Jie Pan, Chunjian Qi

“…In mouse models of Lewis lung cancer (LLC) tumors, combining β-glucan with programmed death-1(PD-1) blocking antibodies led to increase recruitment of CD19+ B cells in the tumor microenvironment (TME), higher numbers of germinal centers B cells (GC B) in the spleen and draining lymph node (DLN), elevate Ig production, and delay tumor progression. …”
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Immunogenicity of HIV-1 <i>Env</i> mRNA and <i>Env-Gag</i> VLP mRNA Vaccines in Mice by Qi Ma, Jing Yang, Xiaoguang Zhang, Hongxia Li, Yanzhe Hao, Xia Feng

“…HIV Env-specific binding and neutralizing antibodies in mouse sera were assessed via enzyme-linked immunosorbent assay (ELISA) and pseudovirus-based neutralization assays, respectively. …”
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Expression, Purification, and Evaluation of Diagnostic Potential and Immunogenicity of a Recombinant NS3 Protein from All Serotypes of Dengue Virus by Laura Mónica Álvarez-Rodríguez, Angel Ramos-Ligonio, José Luis Rosales-Encina, María Teresa Martínez-Cázares, Aurora Parissi-Crivelli, Aracely López-Monteon

“…The fusion proteins were immunogenic, inducing antibodies to be able to recognize to antigens up to a 1 : 3200 dilution. …”
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Progress of CCL20-CCR6 in the airways: a promising new therapeutic target by Ya -Jing Li, Wan-Li Geng, Chen-Chen Li, Jia-Hao Wu, Fei Gao, Yong Wang

“…Numerous studies have demonstrated that therapeutic interventions targeting CCL20 and CCR6, including antibodies and antagonists, have the potential to mitigate disease progression. …”
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Carboxylated Graphene: An Innovative Approach to Enhanced IgA-SARS-CoV-2 Electrochemical Biosensing by Luciana de Souza Freire, Ariamna María Dip Gandarilla, Yonny Romaguera Barcelay, Camila Macena Ruzo, Barbara Batista Salgado, Ana P. M. Tavares, Francisco Xavier Nobre, Julio Nino de Souza Neto, Spartaco Astolfi-Filho, Ștefan Țălu, Pritesh Lalwani, Niranjan Patra, Walter Ricardo Brito

“…We modified screen-printed carbon electrodes (SPCEs) with CG to immobilize the SARS-CoV-2 N-protein, facilitating targeted detection of IgA antibodies (IgA-SARS-CoV-2). The analytical performance was assessed via electrochemical techniques such as cyclic voltammetry and electrochemical impedance spectroscopy, confirming CG synthesis effectiveness and biosensor functionality. …”
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Recombinant Enolase of Trypanosoma cruzi as a Novel Vaccine Candidate against Chagas Disease in a Mouse Model of Acute Infection by Minerva Arce-Fonseca, María Cristina González-Vázquez, Olivia Rodríguez-Morales, Verónica Graullera-Rivera, Alberto Aranda-Fraustro, Pedro A. Reyes, Alejandro Carabarin-Lima, José Luis Rosales-Encina

“…Our results showed that mice vaccinated with rTcENO or its encoding DNA were able to generate typical specific antibodies (IgG1, IgG2a, and IgG2b), suggesting that a mixed Th1/Th2 immune response was induced. …”
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Quantitative fluorescent nanoparticle tracking analysis and nano‐flow cytometry enable advanced characterization of single extracellular vesicles by Danilo Mladenović, Joseph Brealey, Ben Peacock, Kairi Koort, Nataša Zarovni

“…This standardization technique allowed for fluorescent EV signal to be expressed in ERF units (indicative of bound fluorescent antibodies per EV), thus enabling measurement of target protein marker abundance on individual EVs, and in the whole EV population. …”
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Dengue Virus NS1 Protein as a Diagnostic Marker: Commercially Available ELISA and Comparison to qRT-PCR and Serological Diagnostic Assays Currently Used by the State of Florida by Jason H. Ambrose, Shamala Devi Sekaran, Azliyati Azizan

“…Here, real-time molecular assays have proven useful but have limitations, whereas ELISAs that detect antibodies are still favored but results are obtained too late to be of clinical value. …”
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Forkhead Box Protein-3 Gene Expression of Purified Human Peripheral Blood Mononuclear Cells Treated with Methicillin-Resistant Staphylococcus aureus-Somatic Antigens and Hepatitis... by Entidhar A. Hadi, Mohammad A. K. Al-Saadi, Kaiser N. Madlum

“…Background: Optimal hepatitis B virus (HBV) vaccine efficacy linked to producing systemic and mucosal antibodies and cellular immunological memory requires a complete set of immunological responses. …”
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Very Early-Onset Inflammatory Bowel Disease (VEO-IBD) Presenting with Recurrent Leukocytoclastic Vasculitis Preceded by Streptococcal Pharyngitis by Ashley Fonseca, Julee Sunny, Lina M. Felipez

“…She was started on infliximab 10 mg/kg every four weeks after infliximab titers, and antibodies were obtained. Currently, the patient remains on clinical and biochemical remission, with no recent LV episodes or recurrence of streptococcal pharyngitis. …”
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Epidemiological Survey of Toxoplasmosis among Aborted Women in Garmian district, Kurdistan Region, Iraq by Salar Ibrahim Ali

“…The study was carried out in Kalar General Hospital to detect Toxoplasma antibodies among 350 samples, in which 250 samples were from aborted women and 100 samples were from normal birth women as a control. …”
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Analysis of Amino Acid Changes in the Fusion Protein of Virulent Newcastle Disease Virus from Vaccinated Poultry in Nigerian Isolates by Olubukola O. Funsho-Sanni, Elijah E. Ella, Lawal D. Rogo, Olufunsho S. Sanni, Helen I. Inabo, Sodangi A. Luka, Ismaila Shittu

“…Mutation in this A2 antigenic epitope has been reported to induce escape mutation to monoclonal antibodies generated using the NDV LaSota strain. The range of percentage nucleotide and amino acid homology between the study isolates and commercially available vaccine strains is 81.14%–84.39% and 0.175–0.211, respectively. …”
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Maternal Thyroid Dysfunction and Neonatal Thyroid Problems by Hulya Ozdemir, Ipek Akman, Senay Coskun, Utku Demirel, Serap Turan, Abdullah Bereket, Hulya Bilgen, Eren Ozek

“…Women with hypothyroidism and having anti-thyroglobulin (ATG) and anti-thyroid peroxidase (anti-TPO) antibodies were assigned as group I, women with hypothyroidism who did not have autoantibodies were assigned as group II, and women without thyroid problems were assigned as group III. …”
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An atypical presentation of autoimmune hepatitis with delayed menarche in a Nigerian adolescent: a case report by Promise Udoka Asogwa, Bruno Basil, Winifred Njideka Adiri, Nelson Ugwu, Gideon Ekene Anigbo, Evaristus Offia, Casmir Orjioke

“…Following a comprehensive diagnostic workup, including liver function tests, imaging, and autoantibody testing, which were positive for antinuclear and antismooth muscle antibodies, she was correctly diagnosed with type 1 autoimmune hepatitis. …”
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Prevalence and Risk Factors Associated with Hepatitis B and Hepatitis C Infections among Patients Undergoing Hemodialysis: A Single-Centre Study in Somalia by Mohamed Osman Omar Jeele, Rukia Omar Barei Addow, Faduma Nur Adan, Liban Hassan Jimale

“…Age, sex, duration of hemodialysis, number of hemodialysis sessions per week, history of blood transfusion, HbsAg, and anti-HCV antibodies were examined. Results. Out of the 220 patients, males were predominant (113 (51.4%)). …”
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