Transition of Thyroid Autoantibodies by Rituximab Treatment in Women with Rheumatoid Arthritis by Hüseyin Demirci, Ebru Aydoğan, Bilge Ceydilek

“…The decline in thyroid antibodies with the treatment of rituximab reveals the hope that Hashimoto’s thyroiditis may be treatable. …”
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Claudin-4 Undergoes Age-Dependent Change in Cellular Localization on Pig Jejunal Villous Epithelial Cells, Independent of Bacterial Colonization by J. Alex Pasternak, Coral Kent-Dennis, Andrew G. Van Kessel, Heather L. Wilson

“…Mechanisms by which the newborn piglet gut facilitates uptake of colostral cells, antibodies, and proteins may include FcRn and pIgR receptor-mediated endocytosis and paracellular transport between tight junctions (TJs). …”
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A Chinese Family with Familial Dysalbuminemic Hyperthyroxinemia (FDH) due to R242H Mutation on Human Albumin Gene: Reevaluating the Role of FDH in Patients with Asymptomatic Hypert... by Hongbing Liu, Jianmin Ran, Chuping Chen, Guangshu Chen, Ping Zhu, Rongshao Tan, Yan Liu

“…The proband is a 14-year-old girl with light goiter and asymptomatic clinical presentations, whose thyroid function test by a one-step immunoassay showed increased free thyroxine (FT4) and free triiodothyronine (FT3) but nonsuppressed thyrotropin (TSH). All thyroid auto-antibodies were in the normal range. Blood samples were collected from her and most of her immediate family members for target gene sequencing and verification. …”
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Thyroidectomy for Painful Thyroiditis Resistant to Steroid Treatment: Three New Cases with Review of the Literature by Enrico Mazza, Francesco Quaglino, Adolfo Suriani, Nicola Palestini, Cristina Gottero, Renzo Leli, Stefano Taraglio

“…Conversely, in the first patient, thyroid histology showed features of granulomatous thyroiditis, typical of SAT, without fibrosis or lymphocytic infiltration, typical of HT/PHT, coupled to undetectable serum anti-thyroid antibodies. Our data (1) suggest that not only PHT but also SAT may show resistance to steroid treatment and (2) confirm a previous observation in a single PHT patient that increasing prednisone doses above conventional maximal dosages may not be useful in these patients.…”
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Obtaining a pancreatic cancer cell line stably expressing doxycycline-dependent endonuclease Cas9 by A.K. Nurgalieva, V.S. Skripova, L.F. Minigulova, R.G. Kiyamova

“…Cas9 endonuclease expression has been detected by the western blot analysis with antibodies to FLAG epitope. Two tumor clones of the MIA Pa-Ca2/Cas9 cell line expressing Cas9 endonuclease have been generated. …”
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Assessment of access and outcomes of kidney transplantation through the reforms of the Swiss organ allocation system by Massimiliano Bertacchi, Sylvie Ferrari-Lacraz, Jakob Nilsson, Agim Thaqi, Yvan Schmutz, Caroline Wehmeier, Thomas Schachtner, Thomas Mueller, Dela Golshayan, Julien Vionnet, Stefan Schaub, Fadi Haidar, Isabelle Binet, Jutta Thierbach, Urs Wirthmueller, Daniel Sidler, Franz Immer, Jean Villard

“…Initially based on waiting time, HLA compatibility, and crossmatch performed by cell complement-dependent cytotoxicity techniques, the system moved in 2012 to a score including HLA compatibility, waiting time, anti-HLA antibodies detected by the Luminex® technology, and a virtual crossmatch. …”
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Major royal-jelly proteins intake modulates immune functions and gut microbiota in mice by Hang Wu, Shican Zhou, Wenjuan Ning, Xiao Wu, Xiaoxiao Xu, Zejin Liu, Wenhua Liu, Kun Liu, Lirong Shen, Junpeng Wang

“…The splenocytes and mesenteric lymphocytes activated by T-cell mitogens (ConA and anti-CD3/CD28 antibodies) released high levels of IL-2 but low levels of IFN-γ and IL-17A. …”
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Molecular epidemiological analysis of Influenza viruses in Influenza-like illness cases: a retrospective study in Chongqing Hi-Tech Zone, China (2021–2024) by Wei Cai, Yuhang Deng, Pan Xu, Jianjiang Xue

“…Colloidal gold detection of viral antibodies, fluorescent PCR detection of nucleic acids, and gene sequencing were used to identify the different subtypes. …”
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CXCR3, CCR5, and CRTH2 Chemokine Receptor Expression in Lymphocytes Infiltrating Thyroid Nodules with Coincident Hashimoto’s Thyroiditis Obtained by Fine Needle Aspiration Biopsy by Jan Jiskra, Marie Antošová, Jan Krátký, Hana Vítková, Zdeňka Límanová, Helena Marečková, Eliška Potluková

“…The percentage of CRTH2+ lymphocytes was higher in nodules with HT in comparison with controls, both in FNAB samples (13.95 versus 6.7%, p=0.008) and in peripheral blood (6.7 versus 5.13%, p=0.047), and positively correlated with serum antibodies to thyroid peroxidase (r=0.243; p=0.026) and negatively correlated with thyroid volume (r=-0.346; p=0.008). …”
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Insight into the Advances in Clinical Trials of SARS-CoV-2 Vaccines by Syed Mohammed Basheeruddin Asdaq, Shahamah Jomah, Syed Imam Rabbani, Ali Musharraf Alamri, Salman Khalaf Salem Alshammari, Badr Sami Duwaidi, Majed Sadun Alshammari, Abdulhakeem S. Alamri, Walaa F. Alsanie, Majid Alhomrani, Nagaraja Sreeharsha, Mohd. Imran

“…All these vaccines in clinical trials have shown robust production of neutralizing antibodies sufficient to prevent infection. Some of the vaccinated people reported serious complications. …”
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A single residue switch mediates the broad neutralization of Rotaviruses by Yang Huang, Feibo Song, Yuanjun Zeng, Hui Sun, Roufang Sheng, Xuechun Wang, Liqin Liu, Guoxing Luo, Yanan Jiang, Yaling Chen, Mengxuan Zhang, Shiyin Zhang, Ying Gu, Hai Yu, Shaowei Li, Tingdong Li, Qingbing Zheng, Shengxiang Ge, Jun Zhang, Ningshao Xia

“…Abstract Broadly neutralizing antibodies (bNAbs) could offer escape-tolerant and lasting protection against viral infections and therefore guide development of broad-spectrum vaccines. …”
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Morphometric Analysis of Human Embryonic Stem Cell-Derived Ventricular Cardiomyocytes: Determining the Maturation State of a Population by Quantifying Parameters in Individual Cell... by Harvey Y. S. Chan, Wendy Keung, Ronald A. Li, Andrew L. Miller, Sarah E. Webb

“…Cells were double-immunolabeled with α-actinin and COX IV antibodies, to label the myofibrils and mitochondria, respectively, after which images were acquired via confocal microscopy. …”
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T CD3+CD8+ Lymphocytes Are More Susceptible for Apoptosis in the First Trimester of Normal Human Pregnancy by Dorota Darmochwal-Kolarz, Ewelina Sobczak, Piotr Pozarowski, Bogdan Kolarz, Jacek Rolinski, Jan Oleszczuk

“…Lymphocytes were isolated and labeled with anti-CD3, anti-CD4, and anti-CD8 monoclonal antibodies. Apoptosis was detected by CMXRos staining and analyzed using the flow cytometric method. …”
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Essential Microenvironment for Thymopoiesis is Preserved in Human Adult and Aged Thymus by J. Shiraishi, M. Utsuyama, S. Seki, H. Akamatsu, M. Sunamori, M. Kasai, K. Hirokawa

“…To analyze the thymic microenvironment, two monoclonal antibodies (MoAb) were employed. One is MoAb to IL-1 receptor (IL-1R) recognizing medullary and subcapsular cortical epithelial cells of normal infant human thymus. …”
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A Precocious Cerebellar Ataxia and Frequent Fever Episodes in a 16-Month-Old Infant Revealing Ataxia-Telangiectasia Syndrome by Luigi Nespoli, Annapia Verri, Silvia Tajè, Francesco Paolo Pellegrini, Maddalena Marinoni

“…Other investigations showed leukocytopenia with lymphopenia, reduced IgG2 and IgA levels, and low titers of specific postimmunization antibodies against tetanus toxoid and Haemophilus B polysaccharide. …”
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Expression of HGF and c-Met Proteins in Human Keratoconus Corneas by Jingjing You, Li Wen, Athena Roufas, Chris Hodge, Gerard Sutton, Michele C. Madigan

“…Sections were immunolabelled with HGF and c-Met antibodies, visualised using immunofluorescence, and examined with scanning laser confocal microscopy. …”
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Melanoma Development and Progression Are Associated with Rad6 Upregulation and β-Catenin Relocation to the Cell Membrane by Karli Rosner, Darius R. Mehregan, Evangelia Kirou, Judith Abrams, Seongho Kim, Michelle Campbell, Jillian Frieder, Kelsey Lawrence, Brittany Haynes, Malathy P. V. Shekhar

“…Eighty-eight cutaneous tumors, 30 nevi, 29 primary melanoma, and 29 metastatic melanomas, were immunostained with anti-β-catenin and anti-Rad6 antibodies. Strong expression of Rad6 was observed in only 27% of nevi as compared to 100% of primary and 96% of metastatic melanomas. β-Catenin was strongly expressed in 97% of primary and 93% of metastatic melanomas, and unlike Rad6, in 93% of nevi. …”
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Molecular Mechanisms and Therapeutic Prospects of Immunotherapy and Targeted Therapy in Primary Central Nervous System Lymphoma by Lin Zhong MM, Anqing Lu MB, Xiyue Lu MM, Xiaoyin Liu MD, Lujia Cao MM, Shihong Zhu MM, SiJun Diao MM, Xu Cheng MM, Hongwei Wu MB, Jing Chen MD

“…With a deeper understanding of the pathophysiology of PCNSL, various therapies, including CD20 monoclonal antibodies, Bruton's tyrosine kinase (BTK) inhibitors, immunomodulatory drugs, immune checkpoint inhibitors, phosphoinositide 3-kinase (PI3 K)/mammalian target of rapamycin(mTOR) inhibitors, and chimeric antigen receptor (CAR) -T cells are increasingly being applied and have demonstrated considerable efficacy. …”
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Immunophenotyping of Posttraumatic Neutrophils on a Routine Haematology Analyser by Kathelijne Maaike Groeneveld, Marjolein Heeres, Loek Petrus Hendrikus Leenen, Albert Huisman, Leo Koenderman

“…Neutrophils of healthy donors were incubated with antibodies commonly used in trauma research: CD11b (MAC-1), L-selectin (CD62L), FcγRIII (CD16), and FcγRII (CD32) in active form (MoPhab A27). …”
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A Case of De Novo Antiglomerular Basement Membrane Disease Presenting during Pregnancy by F. A. K. Lodhi, T. Akcan, J. N. Mojarrab, S. Sajjad, R. Blonsky

“…Laboratory analysis revealed anemia, life-threatening hyperkalemia, AKI, and elevated antiglomerular basement membrane (GBM) antibodies. Renal biopsy revealed 100% cellular crescents, confirming the diagnosis. …”
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