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3021
Immunomodulatory Properties of HLA-G in Infectious Diseases
Published 2014-01-01“…New therapeutic approaches based on synthetic HLA-G-derived proteins or antibodies are emerging in mouse models of cancer or transplantation, and these new therapeutic tools may eventually prove useful for the treatment of infectious diseases.…”
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3022
Therapeutic Targeting of Fibroblast Growth Factor Receptors in Gastric Cancer
Published 2015-01-01“…Many molecular-targeted therapies inhibiting signaling pathways of various tyrosine kinase receptors have been developed, and monoclonal antibodies targeting human epidermal growth factor receptor 2 (HER2) have become standard therapy for HER2-positive GC. …”
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3023
Conjunctival Lymphangiogenesis Was Associated with the Degree of Aggression in Substantial Recurrent Pterygia
Published 2016-01-01“…Pterygium slices from each patient were immunostained with LYVE-1 monoclonal antibodies to identify lymphatic microvessels in order to calculate the lymphovascular area (LVA), the lymphatic microvessel density (LMD), and the lymphovascular luminal diameter (LVL). …”
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3024
Herpes Simplex Virus Pneumonia: Importance of Aspiration Etiology
Published 2019-01-01“…HSV-1 infection was confirmed by immunostaining with monospecific monoclonal antibodies and by type-specific real-time polymerase chain reaction. …”
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3025
Convalescent plasma therapy in severe coronavirus disease-2019: A narrative review
Published 2020-01-01“…Much before, the concept of transfusing neutralizing antibodies through convalescent blood or plasma was established; this modality demonstrated its effectiveness in containing the havoc caused by diphtheria and tetanus during the early 20th century. …”
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3026
Cytokines and Cytokine Profiles in Human Autoimmune Diseases and Animal Models of Autoimmunity
Published 2009-01-01“…Since a plethora of new treatment approaches using antibodies or small molecule inhibitors specifically targeting cytokines, cellular receptors, or signalling mechanisms has emerged in recent years, more individualized treatment for affected patients may be within reach in the future.…”
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3027
An In Vitro Model of Gastric Inflammation and Treatment with Cobalamin
Published 2017-01-01“…Pernicious anaemia (PA) is an autoimmune condition where antibodies target intrinsic factor and parietal cells, reducing the patient’s ability to absorb cobalamin promoting atrophic gastritis. …”
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3028
Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells
Published 2025-02-01“…We also assessed RA synovial fluid stimulated samples in the presence of various single cytokine neutralizing antibodies or SOC therapeutics, including glucocorticoids, TNF, IL-6 receptor and JAK inhibitors. …”
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3029
Immunohistochemical Expression of Basement Membrane Laminin in Histological Grades of Oral Squamous Cell Carcinoma: A Semiquantitative Analysis
Published 2024-12-01“…Immunohistochemistry was performed using anti-laminin antibodies, and staining intensity was semiquantitatively analyzed using a scoring system. …”
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3030
Rimegepant for the treatment of migraine
Published 2022-10-01“…Novel medications, targeting CGRP, divide into CGRP antibodies and receptor antagonists (gepants). Rimegepant, a second-generation gepant, has shown efficacy in several clinical trials in treating acute migraine. …”
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3031
Rapid Visualization of Human Tumor Xenografts through Optical Imaging with a Near-Infrared Fluorescent Anti–Epidermal Growth Factor Receptor Nanobody
Published 2012-01-01“…A number of studies have employed monoclonal antibodies as probes; however, their characteristic long half-life in the bloodstream has encouraged the development of smaller probes. …”
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3032
The efficacy of an embryonic stem cell-based vaccine for lung cancer prevention depends on the undifferentiated state of the stem cells
Published 2024-12-01“…Our data demonstrate that antibodies against several lung cancer-associated keratin members were enriched in the serum of vaccinated mice. …”
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3033
Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer
Published 2006-01-01“…Seventeen specimens of Crohn's disease dated between 2003/1/1 and 2005/1/1 were collected and underwent immunohistochemical analyses with cylcooxygenase 1, cyclooxygenase 2, 5-lipoxygenase, and 15-lipoxygenase-1 antibodies. Results. (1) The spatial distribution of the three leading enzymes in arachidonic acid pathway—cyclooxygenase 2, 5-lipoxygenase, and 15-lipoxygenase-1—followed sequential arrangement in Crohn's ulcer: neutrophils highly expressing 5-lipoxygenase were in the utmost surface which bordered the band of cyclooxygenase-2 expression that is located just beneath it, and in the lower layers and below the granulation region were eosinophils carrying 15-lipoxygeanse-1. (2) Cyclooxygenase-2 and 15-Lipoxygenase-1-positive cells formed two barrier-like structures that possibly inhibited neutrophil infiltration. …”
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3034
Long-Term Antithyroid Drug Therapy in Smoldering or Fluctuating-Type Graves’ Hyperthyroidism with Potassium Iodide
Published 2024-12-01“…Graves’ hyperthyroidism is characterized by stimulation of the thyroid gland by thyroid-stimulating hormone receptor antibodies (TRAbs). Antithyroid drug (ATD) continuation is recommended as long as the thyroid gland is stimulated. …”
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3035
Growth Hormone Therapy for Small for Gestational Age Short Stature Develops Type 2 Diabetes
Published 2023-01-01“…Blood test results were negative for anti-glutamic acid decarboxylase and anti-islet antigen-2 antibodies. The patient discontinued GH therapy and started diet therapy and oral metformin (500 mg/day) administration. …”
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3036
DEVELOPMENT AND IMPROVEMENT OF ASF SEROLOGICAL DIAGNOSTIC TECHNIQUES
Published 2019-06-01“…The research is devoted to development of rapid test methods for rapid detection of antibodies to ASFV in blood sera of infected animals as well as to analysis of their use effectiveness. …”
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3037
The Proviral Reservoirs of Human Immunodeficiency Virus (HIV) Infection
Published 2024-12-01“…Uncovering the causes of this phenomenon will bring humanity closer to curing HIV infection, potential approaches to which include stem cell transplantation, clustered regularly interspaced short palindromic repeats (CRISPR)/cas9, “Shock and kill”, “Block and lock”, and the application of broad-spectrum neutralizing antibodies (bNAbs).…”
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3038
Treatment of Functional Dyspepsia in Outpatients after COVID-19 Infection
Published 2023-05-01“…All patients were divided in 2 groups by randomization: Group 1 received omeprazole at a dose of 80 mg/day, Group 2 received a combination of omeprazole and Kolofort® (a combined action drug product containing technologically processed antibodies to S100, TNF-alpha, and histamine) at a dose of 80 mg/day. …”
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3039
Bidirectional Interaction of Thyroid-Kidney Organs in Disease States
Published 2020-01-01“…No association between antimicrosomal antibodies with estimated glomerular filtration rate was seen. …”
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3040
Immune Responses to Tissue-Restricted Nonmajor Histocompatibility Complex Antigens in Allograft Rejection
Published 2017-01-01“…., cross-matching) to detect antibodies (Abs) against donor human leukocyte antigens, which has been shown to reduce Ab-mediated hyperacute rejection. …”
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