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2901
Periodontitis and Rheumatoid Arthritis: The Same Inflammatory Mediators?
Published 2019-01-01“…Moreover, the possible role of proinflammatory cytokines, such as TNF and IL6 and autoantibodies, specifically anticyclic citrullinated peptide antibodies, has been examined, suggesting the need to perform further studies to better define this issue.…”
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2902
Validation of a New Saliva Test for Helicobacter pylori Infection
Published 1996-01-01“…The purpose of this study was to evaluate a recently introduced saliva test measuring immunoglobulin (Ig) G antibodies to Helicobacter pylori by enzyme-linked immunosorbent assay (ELISA). …”
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2903
Case Report: Successful treatment of metastatic retinoblastoma with CNS involvement with anti-GD2 immunotherapy, intrathecal topotecan and reduced systemic chemotherapy
Published 2025-01-01“…Despite significant advances, acute and long-term side-effects, particularly in visually impaired and cancer-predisposed patients, underscore the need for additional treatment options. Monoclonal antibodies (mAbs) directed against the tumor-associated antigen GD2 are of considerable interest. …”
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2904
Emergency Splenectomy in a patient with primary immune thrombocytopenia and hemoperitoneum
Published 2013-08-01“…Primary immune thrombocytopenia is an acquired autoimmune disease, with a very variable clinical course, which causes an accelerated destruction by antibodies and an impaired platelet production. A case of a 40 year-old female patient of rural origin with a history of mitral stenosis and atrial fibrillation, diagnosed two months prior to her admission to the Dr. …”
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2905
Bilateral Retrobulbar Optic Neuritis as the First Manifestation of Neuro-Behçet Disease
Published 2020-01-01“…Brain magnetic resonance imaging and the result of cerebrospinal fluid analysis for oligoclonal bands and auto-antibodies were also normal. Pathergy skin test and human leukocyte antigens (HLA) B5 and HLA-B51 were positive. …”
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2906
Modulating cytokine microenvironment during T cell activation induces protective RSV-specific lung resident memory T cells in early life in mice
Published 2024-12-01“…Abstract Maternal immunisation against respiratory viruses provides protection in early life, but as antibodies wane, there can be a gap in coverage. This immunity gap might be filled by inducing pathogen-specific lung tissue-resident T cells (TRM). …”
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2907
Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease
Published 2015-01-01“…Based on the patient’s history, clinical presentation, and radiological findings, serology for cat scratch disease (CSD) was performed and high B. henselae specific IgM and IgG antibodies were detected. Due to its variety of clinical presentations, diagnosis of CSD is challenging, especially in the absence of a history of specific exposure. …”
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2908
Henoch–Schönlein Purpura (IgA Vasculitis) in Association with Thyrotoxicosis
Published 2021-01-01“…Graves’ disease is the most common cause of hyperthyroidism, which is characterized by thyroid antibodies and the following clinical manifestations: goiter, ophthalmopathy, and pretibial myxedema. …”
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2909
Serum Concentration of Interleukin-6 Is Increased Both in Active and Remission Stages of Pemphigus Vulgaris
Published 2008-01-01“…We also found a negative correlation between TNF-α level and pemphigus antibodies titer in the patients from the remission group (rS=−0.47303;P<.02). …”
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2910
Enzymatic hydrolysis of silkworm pupa and its allergenicity evaluation by animal model with different immunization routes
Published 2023-05-01“…The results indicated that the intraperitoneal injection immunization route induced more by detecting with antibodies, histamine and Th2-related cytokines. Moreover, mice treated with silkworm pupa protein peptide displayed no obvious allergic symptoms, indicating that enzyme hydrolytic technique could significantly reduce the allergenicity of silkworm pupa.…”
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2911
Severe Vitamin B12 Deficiency in Pregnancy Mimicking HELLP Syndrome
Published 2019-01-01“…This work-up revealed undetectable vitamin B12 levels and presence of intrinsic factor antibodies, consistent with pernicious anemia. Parenteral B12 supplementation was initiated, with subsequent improvement in hematologic parameters. …”
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2912
Two Cases of Primary Cold Agglutinin Disease Associated with Megaloblastic Anemia
Published 2015-01-01“…Thus, the association of these hematological diseases may be incidental; however, given that CAD is an autoimmune disease which may show antibodies against intrinsic factor and gastric parietal cells, this association was thought to be probably not a coincidence. …”
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2913
Antiphospholipid Syndrome as a Cause of Recurrent Portal Vein Thrombosis in a Man with a Medical History of other Thrombosis
Published 2023-05-01“…During the current examination, APS was suspected, and the result of a blood test for antibodies against phospholipids was positive.Conclusion. …”
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2914
The Origins, Specificity, and Potential Biological Relevance of Human Anti-IgG Hinge Autoantibodies
Published 2011-01-01“…Human anti-IgG hinge (HAH) autoantibodies constitute a class of immunoglobulins that recognize cryptic epitopes in the hinge region of antibodies exposed after proteolytic cleavage, but do not bind to the intact IgG counterpart. …”
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2915
Characterization of Progenitor Cells during Canine Retinal Development
Published 2012-01-01“…We identify the presence of progenitor cells during retinal development in the dog, as this species represents a natural model for studying several breed-specific degenerative retinal disorders. Antibodies to detected progenitor cells (Pax6, C-kit, and nestin) and ganglion cells (BDNF, Brn3a, and Thy1) were used in combination with H3 for the purpose of identifying proliferating cells. …”
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2916
Self-assembled nanoparticles in ocular delivery: a comprehensive review
Published 2025-01-01“…Niosomes can also be surface-modified with ligands (e.g., antibodies, peptides) to target specific ocular tissues or cells and hence can improve drug penetration through the corneal and conjunctival barriers. …”
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2917
Ionizable polymeric micelles (IPMs) for efficient siRNA delivery
Published 2025-01-01“…Moreover, IPMs and FAPi-IPMs mitigate ABC effect and produce fewer PEG antibodies than LNPs, and show minimal apolipoprotein adsorption in vivo compared with LNPs, differentiating their targeting effects from LNPs. …”
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2918
CAR-T CELLS IN CHRONIC LYMPHOCYTIC LEUKEMIA
Published 2024-04-01“… The treatment outcomes of patients with chronic lymphocytic leukemia (CLL) have considerably improved with the introduction of targeted therapies based on Bruton kinase inhibitors (BTKIs), venetoclax, and anti-CD20 monoclonal antibodies. However, despite these consistent improvements, patients who become resistant to these agents have poor outcomes and need new and more productive therapeutic strategies. …”
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2919
Anti-CCP: History and its Usefulness
Published 2005-01-01“…Antibodies directed to cyclic citrullinated peptides (anti-CCP) are highly specific for rheumatoid arthritis (RA) and can easily be detected in sera by using commercially available immunoassays. …”
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2920
Gastroduodenal form of Crohn's disease
Published 2015-10-01“…In difficult cases test for antiSaccharomyces cerevisiae antibodies (ASCA) can be used as additional tool of differential diagnostics. …”
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