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12241
Efficient Hydrolysis of Sugar Beet Pulp Using Novel Enzyme Complexes
Published 2025-01-01“…However, only a fraction of it is currently used, mainly as animal feed. The composition of beet pulp includes plant polysaccharides, such as cellulose, arabinan, and pectin. …”
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12242
Dietary Solid-state-fermentation product of Bacillus velezensis T23 alleviate hepatic steatosis, oxidative stress, gut barrier damage, and microbiota dysbiosis in juvenile genetica...
Published 2025-03-01“…The application of commensal probiotic bacteria is one of the preferable green feed additives for antibiotic substitution in aquaculture, while the application methods and detailed action mechanisms of commensal bacteria isolated from aquatic animals are not consistent with normal mammalian-derived probiotics. …”
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12243
Novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models
Published 2025-01-01“…We show that in two KL mutant NSCLC xenograft models and a KL mutant PDX model, treatment with AHA-1031 monotherapy significantly inhibits tumor growth compared with vehicle-treated animals with no observable toxicity. Tumor tissues from treated mice exhibit significantly increased immune cell infiltrates and activated NK cell populations.Conclusions Activating NK cells through MICA/B stabilization and inducing ADCC offers an alternative and potent therapy option in KL tumors. …”
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12244
Maternal Macronutrient Intake and Associated Risk for Gestational Diabetes Mellitus: Results from the BORN2020 Study
Published 2024-12-01“…Changes from pre-pregnancy to pregnancy showed significant increases in dietary fiber intake (aOR = 1.07, 95%CI: 1.04–1.10), protein (aOR = 1.00, 95%CI: 1.00–1.01), fat (aOR = 1.00, 95%CI: 1.00–1.01), vegetable protein (aOR = 1.01, 95%CI: 1.00–1.03), animal protein (aOR = 1.00, 95%CI: 1.00–1.01), and monounsaturated fatty acid (MUFA) intake (aOR = 1.01, 95%CI: 1.00–1.02), all of which were associated with increased GDM risk. …”
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12245
Longitudinal serological and virological survey of hepatitis E virus in wild boar (Sus scrofa majori, Maremman wild boar) and fallow deer (Dama dama) populations in a protected are...
Published 2024-11-01“…Moreover, our results corroborate that the consumption of undercooked or raw liver from both wild boar and fallow deer, or the direct contact with these animals, could represent a zoonotic risk.…”
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12246
Apoptosis induction and tumor growth suppression by hydroxyapatite nanoparticles–cisplatin combined treatment in Ehrlich solid carcinoma-bearing mice
Published 2025-01-01“…ESC group was administrated distilled water, the HAP-NPs group was treated orally with 100 mg/kg of hydroxyapatite nanoparticles, the CDDP group was administrated intraperitoneally with 5 mg/kg of Cisplatin, the HAP-NPs + CDDP group was treated with both doses of hydroxyapatite and cisplatin, the animal treatment was conducted for 20 days. Antitumor activity was assessed for two durations after 10 and 20 days. …”
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12247
Secreted LGALS3BP facilitates distant metastasis of breast cancer
Published 2025-01-01“…Compared with sensitive cells, xenograft animal experiments with MCF7/TAMR cells showed increased pulmonary metastasis, which completely disappeared in LGALS3BP-knockdown TAMR cells. …”
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12248
Mapping mycological ignorance – checklists and diversity patterns of fungi known for West Africa
Published 2020-07-01“…For several groups of animals and plants, such data are available, but for fungi, especially in tropical regions like West Africa, they are mostly missing. …”
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12249
Revealing the Neuroimaging Mechanism of Acupuncture for Poststroke Aphasia: A Systematic Review
Published 2022-01-01“…After removing the literature studies, animal studies, and case reports, 16 studies were included in the final analysis. …”
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12250
Bentonita como adsorbente de arsénico y plomo en el tracto digestivo de bovinos: estudio in vitro
Published 2024-04-01“…La proporción de bentonita recomendable como quelante de As y Pb es de 1.5%, ya que la dosis de 4.5% afectan la DIVMS y por consiguiente, la productividad animal. …”
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12251
A Neural Circuit From Paraventricular Nucleus of the Thalamus to the Nucleus Accumbens Mediates Inflammatory Pain in Mice
Published 2025-01-01“…The nucleus accumbens (NAc) plays a pivotal role in the regulation of animal behavior, and extensive research has unequivocally demonstrated its significant involvement in the occurrence and development of pain. …”
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12252
Life cycle assessment of agricultural waste recycling for sustainable environmental impact
Published 2024-01-01“…This study considered methods for recycling different agricultural waste streams, such as crop waste, animal manure, pruning materials, and by-products and subsequent uses. …”
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12253
<i>Salmonella enterica</i> serovar Schwarzengrund: Distribution, Virulence, and Antimicrobial Resistance
Published 2025-01-01“…</i> Schwarzengrund by analyzing the sequences of 2058 isolates from both human patients (N = 313) and food- and animal-associated sources, including chicken (N = 1145), turkey (N = 300), pork (N = 132), and other sources (N = 168). …”
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12254
A Risk Management Approach to Global Pandemics of Infectious Disease and Anti-Microbial Resistance
Published 2024-11-01“…The One Health approach recognizes the interconnectedness of human, animal, and environmental health, but is grounded in the biomedical model, which reduces health to the absence of disease. …”
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12255
The viability of treated piggery wastewater for reuse in agricultural irrigation
Published 2024-02-01“…Moreover, the water consumption for swine production is approximately 15 L/animal/day in southern Brazil, resulting in an unsustainable water resource demand. …”
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12256
Comparative abundance and diversity of populations of the Pseudomonas syringae and Soft Rot Pectobacteriaceae species complexes throughout the Durance River catchment from its Fren...
Published 2023-09-01“…The dynamics of human and animal pathogens in catchments have been widely studied in a large variety of contexts allowing the optimization of disease risk reduction. …”
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12257
Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging
Published 2025-01-01“…These alterations in light-dark entrainment were closely associated with dramatic impairment in the Barnes maze test for the entire group of shifted LD mice at middle age, well before cognitive decline was first observed in aged (18-22mo) animals maintained on fixed LD cycles. In conjunction with the effects of circadian dysregulation on cognition, shifted LD mice at middle age were distinguished by significant expansion of splenic B cells and B cell subtypes expressing the activation marker CD69 or inflammatory marker MHC Class II Invariant peptide (CLIP), differential increases in CLIP+, 41BB-Ligand+, and CD74 + B cells in the meningeal lymphatics, alterations in splenic T cell subtypes, and increased number and altered functional state of microglia in the dentate gyrus. …”
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12258
Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer
Published 2019-01-01“…Induction of CIK cells with rPADI4-stimulated DCs elevated the cell proliferation by 50.3% and the ability of CIK cells to kill ECA-109 cells by 14.7% and suppressed tumor volume by 35.1% in the animal model. Conclusion. This study demonstrates that stimulation of DC-CIK cells with PADI4 significantly suppressed tumor growth in tumor-bearing mice by promoting DC maturation, CIK cell proliferation, and cytotoxicity. …”
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12259
PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection
Published 2021-01-01“…The specificity of [18F]TZ4877 was assessed using S1PR1-specific antagonist, NIBR-0213, and S1PR1-specific DsiRNA pretreated the animals. Immunohistochemical studies were performed to confirm the increase of S1PR1 expression in response to infection. …”
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12260
Altered functional brain connectivity in Dyt1 knock-in mouse models
Published 2025-02-01“…We also hypothesized that EMX mice would exhibit altered functional connectivity and activation patterns, supporting the idea that TorsinA dysfunction in the sensorimotor cortex alone can induce network abnormalities. In dGAG animals, we observed significantly lower functional connectivity between key sensorimotor nodes, such as the globus pallidus, somatosensory cortex, thalamus, and cerebellum. …”
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