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10501
Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK and ERK pathwa...
Published 2025-01-01“…Despite its growing use, the neuroimmunological mechanisms underlying ACE treatment effects remain unclear.MethodsThis study investigated the roles and potential mechanisms of the effects of ACE in treating experimental autoimmune encephalomyelitis (EAE), a frequently used animal model of autoimmune neuroinflammation. The effects of ACE treatment were evaluated by monitoring body weight and EAE severity scores. …”
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10502
White adipose tissues and skeletal muscles as a target of chrysin during the treatment of obesity in rats
Published 2025-01-01“…After 8 weeks of treatment, blood samples were taken at the end of the experiment for biochemical tests. Animals were then slaughtered to get white adipose tissue (WAT) and skeletal muscle for analysis of the gene expression of the studied genes. …”
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10503
The Association between Hypertension and Dementia in the Elderly
Published 2012-01-01“…Recent clinical trials and studies on animal models suggest that blockades of RAS system could have reduced cognitive decline seen in Alzheimer's disease and vascular dementia. …”
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10504
Characterization and molecular biological identification of tick species in Nanjing city
Published 2024-12-01“…Tick species composition varied among habitats and animal hosts. No significant genetic variation within tick species was observed.…”
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10505
Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis
Published 2025-01-01“…The effects of the peptide on ccRCC growth and migration were studied through Colony Formation Assay, CCK-8 assay, Transwell Assays, Wound Healing Assay, and animal experiments. Further investigation into the antitumor mechanisms of the peptide was conducted using lentivirus transduction, Western Blot Analysis, qRT-PCR, Immunoprecipitation, Immunofluorescence, and Immunohistochemistry. …”
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10506
Available phosphorus from phosphate extracted from swine wastewater for poultry
Published 2025-02-01“…Afterward, an experiment was carried out with 2,520 broilers, divided in randomized blocks, 9 treatments (0, 0.5, 1.0, 1.5, and 2.0g/kg P from phosphate extracted from swine wastewater and 0.5, 1.0, 1.5, and 2.0g/kg P from dicalcium phosphate), 10 repetitions and 28 birds per experimental unit. The animals’ age was from 1 to 14 days old, which were housed in boxes and fed ad libitum (water and feed). …”
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10507
Reducing Dietary Protein Content by Increasing Carbohydrates Is More Beneficial to the Growth, Antioxidative Capacity, Ion Transport, and Ammonia Excretion of Nile Tilapia (Oreochr...
Published 2023-01-01“…Alkalinity stress is the main stress experienced by aquatic animals in saline–alkali water, which hinders the aquaculture development and the utilization of water resources. …”
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10508
Fostering unsustainability? An analysis of 4-year-olds' dietary impacts in Sweden
Published 2025-01-01“…The dietary impacts of 746 young Swedish children were assessed across ten indicators: carbon footprint, cropland use, new nitrogen and phosphorus inputs, blue water use, ammonia emissions, pesticide use, biodiversity loss, antibiotic use, and animal welfare. This analysis utilized caretaker-reported food intake data from the Riksmaten Young Children study (2021–24). …”
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10509
Simultaneous Quantification of 25-Hydroxyvitamin D3 and 24,25-Dihydroxyvitamin D3 in Rats Shows Strong Correlations between Serum and Brain Tissue Levels
Published 2015-01-01“…The method is highly sensitive, specific, and accurate to quantify 25(OH)D3 and 24,25(OH)2D3 in animal brain tissue. Vitamin D3 metabolites in brain tissue were significantly lower in rats fed with a vitamin D deficiency diet than in rats fed with high vitamin D3 diet. …”
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10510
Pregnancy Promotes Maternal Hippocampal Neurogenesis in Guinea Pigs
Published 2019-01-01“…In guinea pigs, pregnancy lasts ~9 weeks; we set to explore if hippocampal neurogenesis is altered in these animals, relative to gestational stages. Time-pregnant primigravidas (3-5 months old) and age-matched nonpregnant females were examined, with neurogenic potential evaluated via immunolabeling of Ki67, Sp8, doublecortin (DCX), and neuron-specific nuclear antigen (NeuN) combined with bromodeoxyuridine (BrdU) birth-dating. …”
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10511
Systemic Inflammatory Cytokines Predict the Infectious Complications but Not Prolonged Postoperative Ileus after Colorectal Surgery
Published 2018-01-01“…Postoperative ileus (POI) is common after surgery. Animal studies indicate that the POI mechanism involves an inflammatory response, which is also activated during postoperative complications. …”
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10512
Mini meta-analysis of anticholinesterase actions of atorvastatin, simvastatin and rosuvastatin, and in silico identification of their protein targets in Mus musculus
Published 2025-06-01“…The risk of bias scoring was according to those of animal experiments. The effect size (% ChE activity) of statin treatments was significantly decreased by 25.85 % (combined effect size=74.15, p = 0.0001), with significant heterogeneity (Q=1133.19, p < 0.0001, I2=93.73 %). …”
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10513
Investigation of the Protective Effect of Probiotic Lactobacillus plantarum Ep-M17 on the Hepatopancreas of Penaeus vannamei
Published 2024-01-01“…These results underscore the importance of probiotics in controlling aquatic animal diseases and highlight Ep-M17 as a promising dietary supplement for enhancing shrimp health and immunity in aquaculture.…”
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10514
Toxicokinetics and tissue dynamics approaches to evaluate the accumulation and elimination of cadmium in black soldier fly larvae
Published 2025-01-01“…Moreover, the application of a 2-day short-term elimination feeding strategy can significantly elevate the food safety and safety for animal consumption of BSFL.…”
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10515
The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development
Published 2020-01-01“…Although bacterial DNAs play important roles in sepsis development, bacterial DNAs alone are unable to cause severe disease nor lead to death. Priming animals with bacterial DNAs facilitate other pathological factors, such as LPS and other virulent factors, to induce severe disease and lethality. …”
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10516
CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy
Published 2019-01-01“…This study is to explore their role and relationship in podocyte injury of ORG. In animal experiments, the ORG mice developed proteinuria, podocyte injury, and hypertriglyceridemia, accompanied with deregulated lipid metabolism, renal ectopic lipid deposition, activation of NOD-like receptor protein 3 (NLRP3) inflammasome, and secretion of IL-1β of the kidney. …”
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10517
Evaluating the utilization of public art capabilities in cultural-led regeneration (Case study: Oudlajan neighborhood)
Published 2022-03-01“…The results show that permanent and temporary public art promotes economic development, the development of physical aesthetics and socio-cultural development in the Oudlajan neighborhood, among which permanent and most popular exhibitions are the highest in the cafes and restaurants, and the bridge has the least impact. In the interim animated film, the video playback index has the most impact and the least impact is the soundtrack.…”
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10518
Evaluation of 2,3-butanediol derived from whey fermentation as an effective bio-based monomer for waterborne polyurethane dispersions
Published 2025-01-01“…Apart from partial reutilisation in animal feed or some food supplements, the sustainable management and disposal of whey still represent significant environmental challenges. …”
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10519
SPERM QUALITY IN RATS PREDISPOSED TO THE MANIFESTATION OF CATATONIC REACTIONS
Published 2018-07-01“…It is known that selection for behavior including catatonic reactions results in neuroendocrine, reproductive and morphological changes in animals. However, the influence of selection for a catatonic reaction on the spermatogenic function of testes had not been studied. …”
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10520
Fucose as a nutrient ligand for Dikarya and a building block of early diverging lineages
Published 2023-09-01“…The process of fucosylation has been the primary focus in studies relating to fucose in animals due to the presence of fucose in Lewis antigens. …”
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