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10461
Acupuncture Alleviates CUMS-Induced Depression-Like Behaviors by Restoring Prefrontal Cortex Neuroplasticity
Published 2023-01-01“…Chronic unpredictable mild stress- (CUMS-) induced rats were established for the depression animal model. There were a total of four rat groups, including the control group, the CUMS group, the CUMS+acupuncture group, and the CUMS+fluoxetine group. …”
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10462
Prophylactic Role of Averrhoa carambola (Star Fruit) Extract against Chemically Induced Hepatocellular Carcinoma in Swiss Albino Mice
Published 2014-01-01“…A cent percent tumor incidence was noted in carcinogen treated animals while ACE administration resulted in a considerable reduction in tumor incidence, tumor yield, and tumor burden. …”
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10463
O-GlcNAc transferase mediates O-GlcNAcylation of NLRP3 regulates pyroptosis in spinal cord injury
Published 2025-03-01“…Importantly, knockout of OGT mitigated the progression of SCI in an animal model, suggesting a protective role of OGT inhibition in SCI. …”
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10464
A zebrafish model of Ifih1-driven Aicardi–Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients
Published 2023-11-01“…The main challenge for the study of Type I interferonopathies is the lack of a well-founded animal model to better characterize the phenotype as well as to perform fast and large drug screenings to offer the best treatment options. …”
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10465
Gross and applied anatomy pedagogical approaches in occupational therapy education: protocol for a scoping review
Published 2022-06-01“…After title/abstract and full-text screening, included articles will be charted, collated and summarised.Ethics and dissemination This study will not involve human or animal subjects. Therefore, research ethics approval is not required. …”
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10466
The impact of gut microbiome on neuro-autoimmune demyelinating diseases
Published 2024-10-01“…We have examined studies on gut microbiome in patients and animal models and reviewed the existing literature on this topic. …”
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10467
Age-Dependent Switch of the Role of Serotonergic 5-HT1A Receptors in Gating Long-Term Potentiation in Rat Visual Cortex In Vivo
Published 2016-01-01“…While 5-HT application (0.1–10 mM) itself did not alter LTP levels, the broad-acting 5-HT receptor antagonists methiothepin (1 mM) resulted in a clear facilitation of LTP in adult animals, an effect that was mimicked by the selective 5-HT1A receptor antagonist WAY 100635 (1 mM). …”
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10468
Age- and Gender-Based Differences in Nest-Building Behavior and Learning and Memory Performance Measured Using a Radial Six-Armed Water Maze in C57BL/6 Mice
Published 2018-01-01“…In this study, a C57BL/6 mouse animal model was used to study age-based and gender-based behavioral differences using nest building and radial six-armed water maze (RAWM) testing. …”
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10469
A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem
Published 2024-08-01“…The presence of high-quality water is essential not only for human survival but also for the well-being of plants and animals. This research aimed to examine studies investigating the occurrence of antibiotics, endocrine disruptors, and other pharmaceutical products in water, sediments, and organisms within aquatic ecosystems. …”
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10470
Correlation of susceptibility to ortho-aminoazotolueneinduced hepatocarcinogenesis with Car and Ahr signaling pathway activation in mice
Published 2015-12-01“…Male mice of both strains received OAT oil solution at the dose of 225 mg/kg body weight four times within two months. Control animals received the equivalent solvent amount. Mice were sacrificed on days 1 and 4 after the last OAT administration. …”
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10471
Detection and localization of indigenous economic grasses in depth-color close-range aerial images, using a novel trainingless data-to-decision approach (DIKD Hierarchy), for the S...
Published 2025-03-01“…They are associated with fatigue, dehydration, animals' attacks, etc. Plant detection is a pillar of precision agriculture. …”
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10472
Clinical and Epidemiological Characteristics of <i>Staphylococcus caprae</i> Infections in Catalonia, Spain
Published 2025-01-01“…<i>Staphylococcus caprae</i> is a coagulase-negative staphylococcus commonly associated with animals which can also be a zoonotic human pathogen. …”
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10473
Rapid determination of the physiological temperature range for the giant freshwater prawn (Macrobrachium rosenbergii)
Published 2025-03-01“…Electrophysiological methods are used to record the electrocardiogram of animals to convert heart rate; and the signals generated by scaphognathites rubbing electrodes during their movements are used to convert respiratory rate. …”
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10474
Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy
Published 2025-01-01“…These studies provide evidence for an unexpected and novel role for the KCNQ2 pore turret and introduce a valid animal model of KCNQ2 encephalopathy. Our results, spanning structure to behavior, may be broadly applicable because the majority of KCNQ2 encephalopathy patients share variants near the selectivity filter.…”
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10475
Development of fully-resorption replacement paste-like organic/inorganic artificial bones compatible with bone remodeling cycles
Published 2025-03-01“…In this study, varying amounts of PLGA particles were added alongside CSH, and the resulting cement's properties, cytotoxicity, and in vivo response large animals (pigs) were assessed. The cement exhibited a compressive strength of ∼ 30 MPa and set within 15 min, making it suitable for clinical use. …”
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10476
Effect of biogenic polyamines on sliding motility of mycobacteria in the presence of antibiotics
Published 2022-09-01“…This is a serious problem for effective therapy of mycobacteriosis caused by nontuberculosis mycobacteria. Furthermore, animal tissues contain biogenic polyamines, which can increase tolerance of microorganisms to stresses, including antibiotics, and modulate cell motility. …”
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10477
CZYH Alleviates β-Amyloid-Induced Cognitive Impairment and Inflammation Response via Modulation of JNK and NF-κB Pathway in Rats
Published 2019-01-01“…CZYH (200, 400, or 800 mg/kg), donepezil (1.0 mg/kg), or distilled water was given to Aβ25-35-stimulated animals for 17 days consecutively. The Morris water maze test revealed that CZYH (400 or 800 mg/kg) administration improved the Aβ25-35-induced cognitive impairments in rats, and Nissl staining demonstrated that CZYH mitigated the Aβ-caused neuron loss. …”
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10478
Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma
Published 2021-01-01“…Background. Several animal studies have shown the roles of cytokines in regulating liver regeneration following liver resection (LR), which is a type of surgery designed to remove cancerous tumors from the liver. …”
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10479
Recurrent Helicobacter cinaedi bacteremia cured with long-term oral minocycline treatment in a patient undergoing hemodialysis: a case report and literature review
Published 2025-01-01“…Abstract Background Helicobacter cinaedi is a Gram-negative spiral bacillus that inhabits the intestines of animals. First reported in 1984 as the causative agent of proctitis in a homosexual man, it causes bacteremia, cellulitis, and infections in many organs and tissues, particularly in immunocompromised patients. …”
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10480
Protective Efficacy of Decreasing Antigen Doses of a <i>Chlamydia abortus</i> Subcellular Vaccine Against Ovine Enzootic Abortion in a Pregnant Sheep Challenge Model
Published 2025-01-01“…A similar reduction in bacterial shedding of infectious organisms following parturition was observed in the vaccinated groups compared to the challenge control group, which is important in terms of reducing potential transmission to naive animals. Conclusions: The results show that a dose of 10 µg antigen in the vaccine will be optimal in terms of maximising efficacy, reducing shedding at parturition, and ensuring it is cost-effective to produce for commercial manufacture.…”
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