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10381
Advancing biomonitoring of eDNA studies with the Anaconda R package: Integrating soil and One Health perspectives in the face of evolving traditional agriculture practices.
Published 2025-01-01“…Over-represented microbial ASVs associated with both plant and animal pathogens, including those of potential concern for human health, were identified. …”
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10382
Putting one health to the test: Operational challenges and critical reflections from the global South
Published 2025-06-01“…We locate our study in the district of Gyalshing in the state of Sikkim in India, which is a potential zoonoses ‘hotspot’ given its location within the biodiverse Indian Himalayan Region, with numerous avenues for human-animal interactions, and burgeoning human population linked to its tourism-run economy. …”
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10383
Inhibition of growth of colorectal cancer patient-derived subcutaneous xenografts using combined Wnt signaling pathway inhibitor and 5‑fluorouracil
Published 2022-03-01“…Antitumor efficacy of the agents and their combination was studied in xenografts derived from patients with colorectal cancer and subcutaneously implanted in immunodeficient Balb/c Nude mice. All animals with tumors were divided into 4 groups (n = 5): group 1 received 5 fluorouracil 25 mg/kg, group 2 – XAV 939 25 mg/kg, group 3–5 fluorouracil and XAV 939 combination at the same dosages, group 4 was control. …”
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10384
Concept of producing of the Russian national system of functional food
Published 2018-11-01“…The depletion of food products (FP) of vegetable and animal origin in vital mineral elements, vitamins and other physiologically active components represents a serious long-term threat to human health and the national security. …”
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10385
LeaData a novel reference data of leather images for automatic species identification
Published 2025-02-01“…They serve the trade of quality leather products; hence, the knowledge of animal species in leather is inevitable. The traditional identification techniques are prone to ambiguous predictions due to insufficient reference studies. …”
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10386
Adaptive evolution of stress response genes in parasites aligns with host niche diversity
Published 2025-01-01“…Despite this importance, our understanding of the evolution of molecular pathways dealing with environmental stressors in parasitic animals remains limited. Here, we tested the link between adaptive evolution of parasite stress response genes and their ecological diversity and species richness. …”
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10387
Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions
Published 2020-01-01“…Leptin participates in the inflammatory responses in multiple cell types and animal models. Chronic cerebral hypoperfusion (CCH) induces inflammation in the central nervous system (CNS), which acts as one of the main reasons for CCH-induced white matter lesions (WMLs). …”
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10388
Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells
Published 2025-01-01“…In conclusion, small animal studies have demonstrated the feasibility of high-throughput approaches for the discovery of pMHC epitopes recognised by directly alloreactive T cells. …”
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10389
Protective role of vitamin D receptor against mitochondrial calcium overload from PM2.5-Induced injury in renal tubular cells
Published 2025-03-01“…Purpose: This research explores the consequences of being exposed to PM2.5 contribute to renal injury while also evaluating the protective role of Vitamin D-VDR signaling in alleviating mitochondrial calcium imbalance and oxidative stress in renal tubular cells. Methods: Animal models of chronic PM2.5 exposure were used to simulate environmental conditions in wild type and VDR-overexpressing mice specific to renal tubules. …”
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10390
Cottonseed Meal Protein Hydrolysate Improves the Growth Performance of Chinese Mitten Crab (Eriocheir sinensis) by Promoting the Muscle Growth and Molting Performance
Published 2023-01-01“…Plant protein hydrolysates contain a large number of small peptides and free amino acids, which can improve the growth performance of aquatic animals. However, the potential mechanisms are still not well elucidated. …”
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10391
Medicinal plants with neuroprotective potential in East African countries: A systematic review
Published 2025-02-01“…Method: The present study is a systematic review that included randomized controlled trial studies using experimental animal models for various nervous system related conditions treated with medicine plants sourced from within any of the East African countries. …”
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10392
Topical Application of Orabase Bromelain Gel Reduces Inflammatory Process, Bone Loss and Steatosis in Experimental Periodontitis
Published 2025-02-01“…The bromelain-based gel was formulated in two concentrations (1% and 10%). Ten animals were used per group: Control, Periodontitis, Periodontitis + Neutral Gel, Periodontitis + 1% Bromelain Gel, Periodontitis + 10% Bromelain Gel and Periodontitis + 2% Chlorhexidine Gel. …”
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10393
Activation of KATP channels in pain modulation: a systematic review of preclinical studies
Published 2025-01-01“…The main findings of the present systematic review were that KATP channel openers can attenuate induced pain in various animal models and potentiate the effects of analgesics.ConclusionLocal, systemic, spinal, and supraspinal activation of KATP channels can attenuate pain and potentiate the efficacy of analgesic drugs. …”
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10394
Drought and rural communities: strategies to deal with its consequences (Case study: Border Rural of Zahedan Township)
Published 2023-09-01“…The results showed that drought in Zahedan city villages had the greatest effect on reducing water resources, cultivation, employment, income, rural poverty, number of livestock or animal products, rural migration, vegetation loss, erosion and soil salinity and reduced price Had land and land. …”
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10395
Depth-electrode stimulation and concurrent functional MRI in humans: Factors influencing heating with body coil transmission
Published 2025-01-01“…Widely used to map effective functional connectivity in animal studies, its application to the human brain has been limited due to safety concerns. …”
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10396
Chelate compounds and their use for correction of trace element deficiencies in livestock (review)
Published 2024-06-01“…The mechanism of biological action of chelate compounds and the pathogenesis of trace element deficiencies in animals are considered, while the advantages of chelate compound use in microelementoses therapy and prevention are specified.…”
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10397
The guanine nucleotide exchange factor DOCK5 negatively regulates osteoblast differentiation and BMP2-induced bone regeneration via the MKK3/6 and p38 signaling pathways
Published 2025-01-01“…Osteoblast differentiation and bone regeneration were analyzed using bone marrow mesenchymal stem cells (BMSCs) and various animal models. C21 significantly enhanced osteoblast differentiation and mineral deposition in mouse MC3T3-E1 cells and in human and mouse BMSCs. …”
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10398
Effect of dietary lecithin on antioxidant defense of rainbow trout, Oncorhynchus mykiss broodstock and offspring
Published 2024-06-01“…Introduction: Soybean lecithin (SBL) is usually added to aquafeed as a phospholipids source because aquatic animals including crustaceans and fish cannot synthesize phospholipids. …”
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10399
Multidrug-Resistant Salmonella enterica Serovar Rissen Clusters Detected in Azores Archipelago, Portugal
Published 2019-01-01“…In the present study, we analyzed by whole genome sequencing (WGS) all clinical, animal, food, and environmental isolates received up to 2017 in the Portuguese Reference Laboratories. …”
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10400
Characterization of Cantal and Salers Protected Designation of Origin Cheeses Based on Sensory Analysis, Physicochemical Characteristics and Volatile Compounds
Published 2025-01-01“…The PDO Salers cheeses presented the highest flavor variability compared to the PDO Cantal cheeses due to compounds belonging to alcohols, acids, aldehydes and ester conferring ammonia, vegetal and animal flavors compared to the PDO Cantal cheeses that were perceived as more pungent and bitter.…”
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