Dioscin pretreatment ameliorates ferroptosis in cardiomyocytes after myocardial infarction via inhibiting endoplasmic reticulum stress by Chang Wu, Xueping Shen, Pan Lou, Dongyan Song

“…Methods Here, we investigated the potential of Dioscin, a natural compound known for its diverse pharmacological properties, in mitigating ferroptosis in cardiomyocytes following MI by targeting ER stress. Results In animal models subjected to MI, administration of Dioscin notably improved cardiac function, reduced infarct size by approximately 24%, and prevented adverse remodeling, highlighting its therapeutic potential. …”
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Aspergillus fumigatus is responsible for inflammation in a murine model of chronic obstructive pulmonary disease exacerbation by Alexandra Bouyssi, Alexis Trecourt, Tanguy Déméautis, Florence Persat, Olivier Glehen, Martine Wallon, Gilles Devouassoux, Abderrazzak Bentaher, Jean Menotti

“…Methods The inflammatory response to cigarette smoke alone or with A. fumigatus was investigated in cell culture models of murine macrophages and alveolar epithelial cells. In an animal model, mice were exposed daily to two cigarettes smoke over 14 weeks, and two intranasal instillations of 105 spores at weeks 7 and 14. …”
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Larval Cytotoxic and Subacute Toxicity of Gardenia ternifolia, Rourea coccinea, and Cassytha filiformis Used in Traditional Medicine of Benin (West Africa) by E. Agbodjento, J. R. Klotoé, T. I. Sacramento, T. V. Dougnon, E. Déguenon, J. Agbankpé, K. Fabiyi, P. Assogba, M.-P. Hounkanrin, R. Akotegnon, T. J. Dougnon, J.-M. Atègbo

“…Subacute toxicity data indicated that there was no mortality or structural alterations of the liver and kidneys in the lot of treated animals. However, significant alterations in certain hematological and biochemical parameters (hematocrit, ASAT, and uremia) were noted. …”
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Different Approach on our Cells and the Use of CRISPR/Cas 9 Technology: Super Gene'ethic by Ayşenur Taşkaya, Ayşe Nur Akmeşe, Himmet Akkaya, Ece Demirel, Sümeyra Demir, Emine Kav, Şengül Koçer, Elif Senanur Yüksel, Pelin Bacak, Serap Karakaya, Mohammed Saleh Ameen Al Qadri, Hale Köksoy

“…Interestingly, 63.3% showed eagerness for genetically modified plants and animals, while only 9% expressed interest in studies related to eternal youth. …”
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Effect of Pulmonary Rehabilitation on Dyspnoea, Functional Capacity and Thoracic Excursion in Chronic Obstructive Pulmonary Disease: A Case Report by Priyanka K Chilhate, Lajwanti Lalwani (Adwani)

“…Significant occupational dosages include excessive pesticide exposure and home air pollution from burning coal, wood, animal dung and crop residues. Besides medical treatments, pulmonary rehabilitation is crucial for patient recovery from hospital to home. …”
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Rock Art Conservation and Geotourism: A practical example from Foum Chenna engravings site, Morocco by Mohamed Abioui, Lhassan M Barki, Mohammed Benssaou, Abdelkrim Ezaidi, Nezha El Kamali

“…The engravings were predominantly made by pecking out images of human figures, animals and patterns, and the area today is the center of interest for the recently-formed Association of Rock Art Heritage of Southern Morocco, based in Zagora. …”
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Ichthyoarchaeological perspectives on roles of fish and red meat during Indus Civilization in Gujarat, India by G. S. Abhayan, Pramod P. Joglekar, Pramod P. Joglekar, P. Ajithprasad, S. V. Rajesh, Pankaj Goyal, Brad Chase, Jeevan Kharakwal, Prabodh Shirvalkar

“…The roles of animals during the Indus Civilization (circa 4000 BCE to 1300 BCE), which thrived in South Asia, have been extensively studied by zooarchaeologists. …”
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Seroprevalence of Seven Reproductive Diseases in Beef and Dairy Cows from Three Provinces in Indonesia by Didik Tulus Subekti, Mira Fatmawati, Arie Khoiriyah, Arum Pramesthi, Sulinawati Fong, Muhammad Ibrahim Desem, Zul Azmi, Eni Kusumaningtyas, Dwi Endrawati, Eko Setyo Purwanto

“…Control and preventive measures should be focused on high-risk areas and animals like stray cat and dog.…”
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Electrogenic amino acid transport in the intestine of sea bream (Sparus aurata): From functional characterization to physiological effects of Lysophospholipids in aquafeeds by Rocio Robles-Arozarena, Juan Antonio Martos-Sitcha, Laura Bermúdez, Waldo Nuez-Ortín, Juan Fuentes

“…The ex-vivo characterization in Ussing chambers showed a region-dependent electrogenic amino acid transport in the sea bream intestine, being maxima in the mid intestine and with a strong luminal sodium- and pH-dependence. In vivo, the animals were divided into two groups: one was fed a control diet (10 % fishmeal inclusion), whereas the other group was fed with the control diet supplemented with 0.1 % LPL in coated form. …”
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Migraine in men by Mira P. Fitzek, Deirdre M. Boucherie, Tessa de Vries, Cleo Handtmann, Haniyeh Fathi, Bianca Raffaelli, Antoinette MaassenVanDenBrink

“…In contrast, preclinical studies often focus solely in male animals as a result of various misconceptions. This disparity necessitates greater focus on sex-specific aspects of migraine to enhance diagnosis, treatment, and research. …”
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Region-Dependent Alterations in Cognitive Function and ERK1/2 Signaling in the PFC in Rats after Social Defeat Stress by Qiong Wang, Feng Shao, Weiwen Wang

“…These results suggested that social defeat stress was an effective animal model to induce both emotional and cognitive symptoms of depression and that the dysfunction of ERK signaling activities in the PFC might be a potential underlying biological mechanism.…”
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Pursuit on the plane by objects moving away from the trajectory of defending object, with simulation of detection area by A. А. Dubanov, T. V. Ausheev

“…Based on the results of the research, animated images are created. As an example, where the model developed in the article could be in demand, the following can be given. …”
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Canagliflozin alleviates acetaminophen-induced renal and hepatic injury in mice by modulating the p-GSK3β/Fyn-kinase/Nrf-2 and p-AMPK-α/STAT-3/SOCS-3 pathways by Abeer Bishr, Bassant M. El-Mokadem, Asmaa A. Gomaa

“…Cana was given for 5 days; a single dose of APAP was injected on the 6th day, followed by the scarification of animals 24 h later. Key findings: Pre-treatment with Cana ameliorated hepatic and renal functions, whereas, on the molecular levels, Cana promoted hepatic/renal P-AMP-activated protein kinase-α/ protein kinase B (p-Akt)/Glycogen synthase kinase (p-GSK3β) protein expression. …”
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Seagrass macroinvertebrate bycatches support mosquito net trawl fishery in Madagascar by Herinirina Patricia A., Bigot Lionel, Frouin Patrick, Volandrae Huguette T.E, Randriatsara Roddy M., Behivoke Faustinato, Ranivoarivelo Lantoasinoro, Léopold Marc

“…They were sold for human consumption or animal feed, which provided additional income to fishers (USD 1–24 trip−1 and 1–72% of catch income per trip). …”
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Effect of Aloe vera gel on the parotid glands of streptozotocin-induced diabetic albino rats: histological and immunohistochemical study. by Shukria Mohammed Hussein

“…The parotid salivary glands of all animals were dissected after 2 months and prepared for histological and immunohistochemical examinations. …”
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Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters by Yongjun Sui, Swagata Kar, Bhavna Chawla, Tanya Hoang, YuanKai Yu, Shannon M. Wallace, Hanne Andersen, Jay A. Berzofsky

“…As a subunit intranasal COVID-19 vaccine reduced nasopharyngeal virus more than did an intramuscular (IM) vaccine, we hypothesized that this vaccine might reduce onward transmission to others.MethodsWe vaccinated hamsters with either the IM-administrated licensed mRNA vaccine twice or one dose of mRNA IM followed by adjuvanted subunit intranasal vaccine. 24 hours after SARS-CoV-2 challenge, these animals were housed with naïve recipients in a contactless chamber that allows airborne transmission.ResultsOnward airborne transmission was profoundly blocked: the donor and recipients of the intranasal vaccine-boosted group had lower oral and lung viral loads (VL), which correlated with mucosal ACE2 inhibition activity. …”
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Combination of GLP-1 Receptor Activation and Glucagon Blockage Promotes Pancreatic β-Cell Regeneration In Situ in Type 1 Diabetic Mice by Liangbiao Gu, Dandan Wang, Xiaona Cui, Tianjiao Wei, Kun Yang, Jin Yang, Rui Wei, Tianpei Hong

“…Liraglutide, a widely used antidiabetic glucagon-like peptide-1 (GLP-1) analog, has displayed diverse β-cell-protective effects in type 2 diabetic animals. Glucagon receptor (GCGR) monoclonal antibody (mAb), a preclinical agent that blocks glucagon pathway, can promote the recovery of functional β-cell mass in type 1 diabetic mice. …”
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Long-term storage of C-141 reference strain of melioidosis agent (<i>Burkholderia pseudomallei</i>) by E. A. Artemeva, L. A. Melnikova, A. P. Rodionov

“…Melioidosis is a highly dangerous infectious disease caused by Hazard Group II bacteria Burkholderia pseudomallei, against which specific prevention and treatment tools have not been developed yet. Both humans and animals suffer from the disease. Previously the disease was prevalent in Southeast Asia regions, but currently is reported almost in all continents of the globe. …”
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Bacterial diversity impacts as a result of combined sewer overflow in a polluted waterway by O. Calderon, H. Porter-Morgan, J. Jacob, W. Elkins

“…Species found in Newtown Creek include pelagic, marine, human and animal pathogens, hydrocarbonoclastic, and other environmental microbes.…”
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Role of SOCS2 in the Regulation of Immune Response and Development of the Experimental Autoimmune Encephalomyelitis by Allysson Cramer, Bruno Cabral de Lima Oliveira, Paulo Gaio Leite, David Henrique Rodrigues, Fatima Brant, Lisia Esper, Pollyana Maria Oliveira Pimentel, Rafael Machado Rezende, Milene Alvarenga Rachid, Antonio Lucio Teixeira, Ana Maria Caetano Faria, Mauro Martins Teixeira, Fabiana Simão Machado

“…Experimental Autoimmune Encephalomyelitis (EAE) is the most widely used animal model for the study of MS. The Suppressor of Cytokine Signaling (SOCS) 2 protein plays a critical role in regulating the immune responses. …”
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