-
121
Form and Function of Sleep Spindles across the Lifespan
Published 2016-01-01“…Despite a broad general understanding of mechanisms of spindle generation gleaned from animal studies, the mechanisms underlying certain features of spindles in the human brain, such as “global” versus “local” spindles, are largely unknown. …”
Get full text
Article -
122
Mechanism of Human Tooth Eruption: Review Article Including a New Theory for Future Studies on the Eruption Process
Published 2014-01-01“…Accordingly, the mechanism of eruption depends on the correlation between space in the eruption course, created by the crown follicle, eruption pressure triggered by innervation in the apical root membrane, and the ability of the periodontal ligament to adapt to eruptive movements. Animal studies and studies on normal and pathological eruption in humans can support and explain different aspects in the new theory. …”
Get full text
Article -
123
Gene Therapy: A step toward advanced orthodontics – A narrative review
Published 2023-07-01“…After the introduction of gene therapy in dentistry, this field is also flourishing rapidly in the branch of orthodontics and dentofacial orthopedics as it can prevent many prenatal and postnatal dentofacial anomalies which have the genetical etiology. Despite various animal studies showing promising results, a lot more is left to be explored. …”
Get full text
Article -
124
Epithelial Tight Junctional Changes in Colorectal Cancer Tissues
Published 2011-01-01“…This review will present recent data from clinical and animal studies showing how altered TJ protein expression is a feature of certain CRCs. …”
Get full text
Article -
125
Do NSAIDs Prevent Colorectal Cancer?
Published 2000-01-01“…This observation is supported by animal studies that show fewer tumours per animal and fewer animals with tumours after administration of several different NSAIDs. …”
Get full text
Article -
126
Lutein, Zeaxanthin, and meso-Zeaxanthin in the Clinical Management of Eye Disease
Published 2015-01-01“…Subsequently, the effect of xanthophylls in the prevention and treatment of various eye diseases has been examined through epidemiological studies, animal studies, and clinical trials. This paper attempts to review the epidemiological studies and clinical trials investigating the effects of xanthophylls on the incidence and progression of various eye diseases. …”
Get full text
Article -
127
Animal-based evidence supports protective activity of bioengineered silver and gold nanomaterials on hepatic and renal function profile parameters
Published 2025-01-01“…This review highlights the emerging role of eco-friendly, bioengineered silver (AgNPs) and gold nanoparticles (AuNPs) as protective agents for liver and kidney health, based on evidence from animal studies. The discussion emphasizes green synthesis approaches, which offer sustainable and biocompatible routes for nanoparticle production. …”
Get full text
Article -
128
The Role of Mitochondria from Mature Oocyte to Viable Blastocyst
Published 2013-01-01“…Mitochondrial augmentation of oocytes is now reconsidered in light of our current understanding of mitochondrial function and the publication of a number of animal studies. With a better understanding of the role of this organelle in oocytes immediately after fertilization, blastocyst and offspring, mitochondrial augmentation may be reconsidered as a method to improve oocyte quality.…”
Get full text
Article -
129
Gut Microbiome in Obsessive Compulsive Disorder: Potential of Probiotics as an Adjuvant Therapy
Published 2022-11-01“…As an approach to restoring the balance of the gut microbiome, probiotics serve as an effective solution. In vivo animal studies showed that probiotics can potentially improve OCD symptoms. …”
Get full text
Article -
130
Clinical Effect of Photobiomodulation on Wound Healing of Diabetic Foot Ulcers: Does Skin Color Needs to Be Considered?
Published 2022-01-01“…A literature search was conducted and resulted in articles on cell studies, animal studies, and clinical trials. Only 13 clinical trials and 2 clinical case studies were adopted and used in this review. …”
Get full text
Article -
131
The Heart-Placenta Axis in the First Month of Pregnancy: Induction and Prevention of Cardiovascular Birth Defects
Published 2013-01-01“…Extrapolating from animal studies to human pregnancy, our studies showed that folate (FA) deficiency as well as one-time exposure to environmental factors in the first two to three weeks of human gestation can result in severe congenital heart defects (CHDs). …”
Get full text
Article -
132
Nanomodified Peek Dental Implants: Bioactive Composites and Surface Modification—A Review
Published 2015-01-01“…Melt-blending with bioactive nanoparticles can be used to produce bioactive nanocomposites, while spin-coating, gas plasma etching, electron beam, and plasma-ion immersion implantation can be used to modify the surface of PEEK implants in order to make them more bioactive. However, more animal studies are needed before these implants can be deemed suitable to be used as dental implants.…”
Get full text
Article -
133
Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa
Published 2025-01-01“…Although underscored by animal studies, the endotypes of human RDEB are poorly understood. …”
Get full text
Article -
134
Targeting gut microbiota in osteoporosis: impact of the microbial-based functional food ingredients
Published 2024-01-01“…Moreover, additional animal studies and clinical trials are needed to understand the interactions between gut microbiota and bone metabolism before further applications.…”
Get full text
Article -
135
MOF-derived intelligent arenobufagin nanocomposites with glucose metabolism inhibition for enhanced bioenergetic therapy and integrated photothermal-chemodynamic-chemotherapy
Published 2025-01-01“…Additionally, it significantly promoted cell apoptosis by upregulating pro-apoptotic proteins such as Bax, Bax/Bcl-2, cytochrome C. Animal studies have shown that the tumor inhibition efficiency of ZIAMH nanomedicines was three fold higher than that of free drugs. …”
Get full text
Article -
136
Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss
Published 2016-01-01“…Here, we provide a brief review to address several critical issues related to NIHHL: (1) the mechanism of noise induced synaptic damage, (2) reversibility of the synaptic damage, (3) the functional deficits as the nature of NIHHL in animal studies, (4) evidence of NIHHL in human subjects, and (5) peripheral and central contribution of NIHHL.…”
Get full text
Article -
137
A General Overview of Mesenchymal Stem Cell Therapies in Drug- and Chemical-Induced Liver Injury Models
Published 2024-04-01“…To understand the molecular mechanisms of MSCs’ effects on liver injury, animal studies are required to drive research perspectives for future progress.…”
Get full text
Article -
138
Management of Maillard reaction-derived reactive carbonyl species and advanced glycation end products by tea and tea polyphenols
Published 2022-05-01“…By analyzing recent publications, we have covered across chemistry models, cell lines and animal studies. Tea polyphenols, particularly catechins, showed outstanding antiglycation effect by trapping α-dicarbonyl compounds and impeding AGEs formation. …”
Get full text
Article -
139
The Anti-Inflammatory Role of Vitamin E in Prevention of Osteoporosis
Published 2012-01-01“…Anticytokine therapy using cytokine antagonists such as IL-receptor antagonist and TNF-binding protein was able to suppress the activity of the respective cytokines and prevent bone loss. Several animal studies have shown that vitamin E in the forms of palm-derived tocotrienol and α-tocopherol may prevent osteoporosis in rat models by suppressing IL-1 and IL-6. …”
Get full text
Article -
140
Therapeutic Potential of HGF-Expressing Human Umbilical Cord Mesenchymal Stem Cells in Mice with Acute Liver Failure
Published 2016-01-01“…However, the efficacy of this cell therapy in animal studies needs to be significantly improved before it can be translated into clinics. …”
Get full text
Article
